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Volumn 32, Issue 3, 1997, Pages 255-262

Simvastatin impairs mitogen-induced proliferation of malignant B- lymphocytes from humans-in vitro and in vivo studies

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MEVINOLIN; MITOGENIC AGENT; PRAVASTATIN; SIMVASTATIN;

EID: 0030978664     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-997-0032-1     Document Type: Article
Times cited : (36)

References (27)
  • 2
    • 0017354135 scopus 로고
    • The Low-Density Lipoprotein Pathway and Its Relation to Atherosclerosis
    • Goldstein, J.L., and Brown, M.S. (1977) The Low-Density Lipoprotein Pathway and Its Relation to Atherosclerosis, Ann Rev. Biochem. 46, 897-930.
    • (1977) Ann Rev. Biochem. , vol.46 , pp. 897-930
    • Goldstein, J.L.1    Brown, M.S.2
  • 3
    • 0018181378 scopus 로고
    • Low Density Lipoprotein (LDL) Receptor Activity in Human Acute Myelogenous Leukemia Cells
    • Ho, Y., Smith, G., Brown, M., and Goldstein, J. (1978) Low Density Lipoprotein (LDL) Receptor Activity in Human Acute Myelogenous Leukemia Cells, Blood 52, 1099-1114.
    • (1978) Blood , vol.52 , pp. 1099-1114
    • Ho, Y.1    Smith, G.2    Brown, M.3    Goldstein, J.4
  • 4
    • 0021260784 scopus 로고
    • Elevated Low Density Lipoprotein Receptor Activity in Leukemic Cells with Monocytic Differentiation
    • Vitols, S., Gahrton, G., Öst, Å., and Peterson, C. (1984) Elevated Low Density Lipoprotein Receptor Activity in Leukemic Cells with Monocytic Differentiation, Blood 63, 1186-1193.
    • (1984) Blood , vol.63 , pp. 1186-1193
    • Vitols, S.1    Gahrton, G.2    Öst, Å.3    Peterson, C.4
  • 5
    • 0023895738 scopus 로고
    • Impaired Low-Density Lipoprotein Receptor Activity in Chronic B-Lymphocytic Leukaemia Cells
    • Juliusson, G., and Vitols, S. (1988) Impaired Low-Density Lipoprotein Receptor Activity in Chronic B-Lymphocytic Leukaemia Cells, Eur. J. Haematol. 40, 18-24.
    • (1988) Eur. J. Haematol. , vol.40 , pp. 18-24
    • Juliusson, G.1    Vitols, S.2
  • 6
    • 0025814690 scopus 로고
    • In vivo Regulation of Human Leukocyte 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase: Increased Enzyme Protein Concentration and Catalytic Efficiency in Human Leukemia and Lymphoma
    • Harwood, H.J., Alvarez, I.M., Noyes, W.D., and Stacpoole, P.W. (1991) In vivo Regulation of Human Leukocyte 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase: Increased Enzyme Protein Concentration and Catalytic Efficiency in Human Leukemia and Lymphoma, J. Lipid. Res. 32, 1237-1252.
    • (1991) J. Lipid. Res. , vol.32 , pp. 1237-1252
    • Harwood, H.J.1    Alvarez, I.M.2    Noyes, W.D.3    Stacpoole, P.W.4
  • 7
    • 33745026603 scopus 로고
    • The Distribution and Chemical Composition of Ultracentrifugally Separated Lipoproteins in Human Serum
    • Havel, R.J., Eder, H.A., and Bragdon, J.H. (1955) The Distribution and Chemical Composition of Ultracentrifugally Separated Lipoproteins in Human Serum, J. Clin. Invest. 34, 1345-1353.
    • (1955) J. Clin. Invest. , vol.34 , pp. 1345-1353
    • Havel, R.J.1    Eder, H.A.2    Bragdon, J.H.3
  • 8
    • 0015348455 scopus 로고
    • The Metabolism of Low Density Lipoprotein in Familial Type II Hyperlipoproteinemia
    • Langer, T., Strober, W., and Levy, R.I. (1972) The Metabolism of Low Density Lipoprotein in Familial Type II Hyperlipoproteinemia, J. Clin. Invest. 51, 1528-1536.
    • (1972) J. Clin. Invest. , vol.51 , pp. 1528-1536
    • Langer, T.1    Strober, W.2    Levy, R.I.3
  • 9
    • 0020973547 scopus 로고
    • Receptor-Mediated Endocytosis of Low-Density Lipoprotein in Cultured Cells
    • Goldstein, J.L., Basu, S.K., and Brown, M.S. (1983) Receptor-Mediated Endocytosis of Low-Density Lipoprotein in Cultured Cells, Methods Enzymol. 98, 241-260.
    • (1983) Methods Enzymol. , vol.98 , pp. 241-260
    • Goldstein, J.L.1    Basu, S.K.2    Brown, M.S.3
  • 12
    • 0017350190 scopus 로고
    • Cholesterol Determination in High-Density Lipoproteins Separated by Three Different Methods
    • Lopes, V.M., Stone, P., Ellis S., and Colwell, J.A. (1977) Cholesterol Determination in High-Density Lipoproteins Separated by Three Different Methods. Clin. Chem. 23, 882-884.
    • (1977) Clin. Chem. , vol.23 , pp. 882-884
    • Lopes, V.M.1    Stone, P.2    Ellis, S.3    Colwell, J.A.4
  • 13
    • 0018652133 scopus 로고
    • Induction of Monoclonal Antibody Synthesis in Malignant Human B Cells by Polyclonal B Cell Activators. Relationship between B Cell Subsets and Prognosis
    • Robert, K.H. (1979) Induction of Monoclonal Antibody Synthesis in Malignant Human B Cells by Polyclonal B Cell Activators. Relationship Between B Cell Subsets and Prognosis, Immunol. Rev. 48, 123-143.
    • (1979) Immunol. Rev. , vol.48 , pp. 123-143
    • Robert, K.H.1
  • 14
    • 0018946008 scopus 로고
    • Nonrandom Chromosomal Aberrations in Chronic Lymphocytic Leukemia Revealed by Polyclonal B-Cell-Mitogen Stimulation
    • Gahrton, G., Robert, K.H., Friberg, K., Zech, L., and Bird, A.G. (1980) Nonrandom Chromosomal Aberrations in Chronic Lymphocytic Leukemia Revealed by Polyclonal B-Cell-Mitogen Stimulation, Blood 56, 640-647.
    • (1980) Blood , vol.56 , pp. 640-647
    • Gahrton, G.1    Robert, K.H.2    Friberg, K.3    Zech, L.4    Bird, A.G.5
  • 15
    • 0020519366 scopus 로고
    • Chronic Lymphocytic Leukaemia Cells Activated in vitro Reveal Cellular Changes That Characterize B-Prolymphocytic Leukaemia and Immunocytoma
    • Robert, K.H., Juliusson, G., and Biberfeld, P. (1983) Chronic Lymphocytic Leukaemia Cells Activated in vitro Reveal Cellular Changes That Characterize B-Prolymphocytic Leukaemia and Immunocytoma, Scand. J. Immunol. 17, 397-401.
    • (1983) Scand. J. Immunol. , vol.17 , pp. 397-401
    • Robert, K.H.1    Juliusson, G.2    Biberfeld, P.3
  • 16
    • 0020691882 scopus 로고
    • Mitogen-Induced Switching of Immunoglobulin Heavy-Chain Class Secretion in Chronic B-Lymphocytic Leukaemia and Immunocytoma Cell Populations
    • Juliusson, G., Robert, K.H., Hammarstrom, L., Smith, C.I., Biberfeld, G., and Gahrton, G. (1983) Mitogen-Induced Switching of Immunoglobulin Heavy-Chain Class Secretion in Chronic B-Lymphocytic Leukaemia and Immunocytoma Cell Populations, Scand. J. Immunol. 17, 51-59.
    • (1983) Scand. J. Immunol. , vol.17 , pp. 51-59
    • Juliusson, G.1    Robert, K.H.2    Hammarstrom, L.3    Smith, C.I.4    Biberfeld, G.5    Gahrton, G.6
  • 17
    • 0028090689 scopus 로고
    • Multilevel Regulation of Low-Density Lipoprotein Receptor and 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene Expression in Normal and Leukemic Cells
    • Vitols, S., Norgren, S., Juliusson, G., Tatidis, L., and Luthman, H. (1994) Multilevel Regulation of Low-Density Lipoprotein Receptor and 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene Expression in Normal and Leukemic Cells, Blood 84, 2689-2698.
    • (1994) Blood , vol.84 , pp. 2689-2698
    • Vitols, S.1    Norgren, S.2    Juliusson, G.3    Tatidis, L.4    Luthman, H.5
  • 18
    • 0025009814 scopus 로고
    • Inhibition by 6-Fluoromevalonate Demonstrates That Mevalonate or One of the Mevalonate Phosphates Is Necessary for Lymphocyte Proliferation
    • Cuthbert, J.A., and Lipsky, P.E. (1990) Inhibition by 6-Fluoromevalonate Demonstrates That Mevalonate or One of the Mevalonate Phosphates Is Necessary for Lymphocyte Proliferation, J. Biol. Chem. 265, 18568-18575.
    • (1990) J. Biol. Chem. , vol.265 , pp. 18568-18575
    • Cuthbert, J.A.1    Lipsky, P.E.2
  • 20
    • 0022413876 scopus 로고
    • Suppression of Murine Neuroblastoma Growth in vivo by Mevinolin, a Competitive Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase
    • Maltese, W.A., Defendini, R., Green, R.A., Sheridan, K.M., and Donley, D.K. (1985) Suppression of Murine Neuroblastoma Growth in vivo by Mevinolin, a Competitive Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase, J. Clin. Invest. 76, 1748-1754.
    • (1985) J. Clin. Invest. , vol.76 , pp. 1748-1754
    • Maltese, W.A.1    Defendini, R.2    Green, R.A.3    Sheridan, K.M.4    Donley, D.K.5
  • 21
    • 0028535302 scopus 로고
    • Selective Inhibition of Primary Acute Myeloid Leukaemia Cell Growth by Simvastatin
    • Newman, A., Clutterbuck, R.D., Powles, R.L., and Millar, J.L. (1994) Selective Inhibition of Primary Acute Myeloid Leukaemia Cell Growth by Simvastatin, Leukemia 8, 2023-2029.
    • (1994) Leukemia , vol.8 , pp. 2023-2029
    • Newman, A.1    Clutterbuck, R.D.2    Powles, R.L.3    Millar, J.L.4
  • 22
    • 0027399622 scopus 로고
    • Reversal of Ras-Induced Inhibition of Gap-Junctional Intercellular Communication, Transformation, and Tumorigenesis by Lovastatin
    • Ruch, R.J., Madhukar, B.V., Trosko, J.E., and Klaunig, J.E. (1993) Reversal of Ras-Induced Inhibition of Gap-Junctional Intercellular Communication, Transformation, and Tumorigenesis by Lovastatin, Mol. Carcinog. 7, 50-59.
    • (1993) Mol. Carcinog. , vol.7 , pp. 50-59
    • Ruch, R.J.1    Madhukar, B.V.2    Trosko, J.E.3    Klaunig, J.E.4
  • 23
    • 0024316475 scopus 로고
    • Genetic and Pharmacological Suppression of Oncogenic Mutations in Ras Genes of Yeast and Humans
    • Schafer, W.R., Kim, R., Sterne, R., Thorner, J., Kim, S.H., and Rine, J. (1989) Genetic and Pharmacological Suppression of Oncogenic Mutations in Ras Genes of Yeast and Humans, Science 245, 379-385.
    • (1989) Science , vol.245 , pp. 379-385
    • Schafer, W.R.1    Kim, R.2    Sterne, R.3    Thorner, J.4    Kim, S.H.5    Rine, J.6
  • 24
    • 0023927642 scopus 로고
    • Oncogenes in Chronic Lymphocytic Leukemia
    • Butturini, A., and Gale, R.P. (1988) Oncogenes in Chronic Lymphocytic Leukemia, Leuk. Res. 12, 89-92.
    • (1988) Leuk. Res. , vol.12 , pp. 89-92
    • Butturini, A.1    Gale, R.P.2
  • 26
    • 0027987849 scopus 로고
    • Randomised Trial of Cholesterol Lowering in 4444 Patients with Coronary Heart Disease: The Scandinavian Simvastatin Survival Study (4S)
    • The Scandinavian Simvastatin Survival Study Group (1994) Randomised Trial of Cholesterol Lowering in 4444 Patients with Coronary Heart Disease: The Scandinavian Simvastatin Survival Study (4S), Lancet 344, 1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 27
    • 0025077819 scopus 로고
    • Simvastatin. A Review of Its Pharmacological Properties and Therapeutic Potential in Hypercholesterolaemia
    • Todd, P.A., and Goa, K.L. (1990) Simvastatin. A Review of Its Pharmacological Properties and Therapeutic Potential in Hypercholesterolaemia, Drugs 40, 583-607.
    • (1990) Drugs , vol.40 , pp. 583-607
    • Todd, P.A.1    Goa, K.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.