In vivo antigenotoxic effects of dietary allyl sulfides in the rat

Cancer Letters

Volumn 114, Issue 1-2, 1997, Pages 131-134

  Le Bon, Anne Marie ^a   Roy, Corinne ^a   Dupont, Christine ^a   Suschetet, Marc ^a  

^a CEMAGREF   (France)

Author keywords

Aflatoxin B1; Allyl sulfides; Ames test; DNA single strand breaks; N Nitrosodimethylamine

Indexed keywords

AFLATOXIN B1; ALLYL SULFIDE; DIALLYL DISULFIDE; DIMETHYLNITROSAMINE; DNA; METHYLNITROSOUREA; THIOL;

AMES TEST; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DIET; DNA STRAND BREAKAGE; GENOTOXICITY; MALE; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SALMONELLA TYPHIMURIUM;

AFLATOXIN B1; ALLYL COMPOUNDS; ANIMALS; ANTICARCINOGENIC AGENTS; ANTIMUTAGENIC AGENTS; DIMETHYLNITROSAMINE; DISULFIDES; DNA DAMAGE; LIVER; MALE; METHYLNITROSOUREA; MUTAGENICITY TESTS; MUTAGENS; RATS; SALMONELLA TYPHIMURIUM; SULFIDES;

ANIMALIA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0030977687     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)04642-9     Document Type: Conference Paper

References (10)

1. Steinmetz, K.A., Kushi, L.H., Bostick, R.M., Folson, A.R. and Potter, J.D. (1994) Vegetables, fruit, and colon cancer in the Iowa women's health study. Am. J. Epidemiol., 139, 1-15.
2. Wargovich, M.J. (1992) Inhibition of gastrointestinal cancer by organosulfur compounds in garlic. In: Cancer Chemoprevention, pp 195-203. Editors: L.W. Wattenberg, M. Lipkin, C.W. Boone and G.J. Kelloff. CRC Press, Boca Raton, FL.
3. Brady, J.F., Li, D., Ishizaki, H. and Yang, C.S. (1988) Effect of diallyl sulfide in rat liver microsomal nitrosamine metabolism and other monooxygenase activities. Cancer Res., 48, 5937-5940.
4. Haber, D., Siess, M.H., De Waziers, I., Beaune, P. and Suschetet, M. (1994) Modification of hepatic drug-metabolizing enzymes in rat fed naturally occuring allyl sulphides. Xenobiotica, 24, 169-182.
5. Haber-Mignard, D., Suschetet, M., Berges, R., Astorg, P. and Siess, M.H. (1996) Inhibition of aflatoxin B1 and N-nitrosodiethylamine-induced liver preneoplastic foci in rats fed naturally occuring allyl sulfides. Nutr. Cancer, 25, 61-70.
6. Maron, D.M. and Ames, B.N. (1983) Revised methods for the Salmonella mutagenicity test. Mutat. Res., 113, 173-215.
7. Kohn, K.W., Erickson, L.C., Ewig, R.A.G. and Friedman, C.A. (1976) Fractionation of DNA from mammalian cells by alkaline elution. Biochemistry, 15, 4629-4637.
8. Cesarone, C.F., Bolognesi, C. and Santi, L. (1979) Improved microfluorimetric DNA determination in biological material using 33258 Hoechst. Anal. Biochem., 100, 188-197.
9. Lin, D.X., Malaveille, C., Park, S.S., Gelboin, H.V. and Bartsch, H. (1990) Contribution of DNA methylation and benzylation to N-nitroso-N-benzyl-methylamine-induced mutagenesis in bacteria: effects of rat liver cytochrome P450 isozymes and glutathione transferases. Carcinogenesis, 11, 1653-1658.
10. Hamilton, J.W. and Bloom, S.E. (1986) Correlation between induction of xenobiotic metabolism and DNA damage from chemical carcinogens in the chick embryo in vivo. Carcinogenesis, 7, 1101-1106.