Synthesis and immunological properties of Vi and Di-O-acetyl pectin protein conjugates with adipic acid dihydrazide as the linker

Infection and Immunity

Volumn 65, Issue 6, 1997, Pages 2088-2093

  Kossaczka, Zuzana ^a,c   Bystricky, Slavomir ^a,c   Bryla, Dolores A ^a   Shiloach, Joseph ^b   Robbins, John B ^a   Szu, Shousun C ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPIC ACID; PECTIN;

ACETYLATION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BACTERIUM CONJUGATION; CROSS LINKING; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC RECOMBINATION; IMMUNOGENICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; TYPHOID FEVER; VACCINATION;

EID: 0030977286     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.6.2088-2093.1997     Document Type: Article

References (41)

1. Acharya, I. L., C. U. Lowe, R. Thapa, V. L. Gurubacharya, M. B. Shrestha, M. Cadoz, D. Schulz, J. Armand, D. A. Bryla, B. Trollfors T. Cramton, R. Schneerson, and J. B. Robbins. 1987. Prevention of typhoid fever in Nepal with the cnpsular polysaccharidc of Salmonella typhi. N. Engl. J. Med. 317: 1101-1104.
2. Anderson, P., M. E. Pichichero, and R. A. Insel. 1985. Immunogens consisting of oligosaccharides from the capsule of Haemophilius influenzae type b coupled to diphtheria toxoid or the toxin protein CRM197. J. Clin. Invest. 76:52-59.
3. Anderson, P. W., M. E. Pichichero, R. A. Insel, R. Betts, R. Eby, and D. H. Smith. 1986. Vaccines consisting of periodate-cleavcd oligosaceharides from the capsule of Haemophilus inflnenzae type b coupled to a protein carrier: structural and temporal requirements for priming in the human infant. J. Immunol. 137:1181-1186.
4. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
5. Bystricky, S., and S. C. Szu. 1994. O-acetylation affects the binding properties of the carboxyl groups on the Vi bacterial polysaccharide. Biophys. Chem. 51:1-7.
6. Chihara, G., Y. Y. Maeda, and J. Hamuro. 1982. Current status and perspectives of immunomodulators of microbial origin. Int. J. Tissue React. 4:207-225.
7. Chu, C., R. Schneerson, J. B. Robblns, and S. C. Rastogi. 1983. Further studies on the immunogenicity of Haemophilus influenzae type b and pneumococcal type 6A polysaccharide-protein conjugates. Infect. Immun. 40: 245-256.
8. Devi, S. J. N., J. B. Robbins, and R. Schneerson. 1991. Antibodies to poly [(2→8)-α-N-acetylneuraminic acid] and poly[{2→9)-α-N-acetylneuraminic acid] are elicited by immunization of mice with Escherichia coli K92 conjugates: potential vaccines for groups B and C meningococci and E. coli K1. Proc. Natl. Acad. Sci. USA 88:7175-7179.
9. Di Luzio, N. R. 1983. Immunopharmacology of glucan: a broad spectrum enhancer of host defense mechanisms. Trends Pharmacol. Sci. 4:344-347.
10. Fattom, A., J. Shiloach, D. Bryla, D. Fitzgerald, I. Pastan, W. W. Karakawa, J. B. Robbins, and R. Schneerson. 1992. Comparative immunogenicity of conjugates composed of the Staphylococcus aureus type 8 capsular polysaccharide bound to carrier proteins by adipic acid dihydrazide or N-succinimidyl-3-(2-pyridyldithio)propionate. Infect. Immun. 60:584-589.
11. Hestrin, S. 1949. The reaction of acetylcholine and other carboxylic acid derivatives with hydroxylamine, and its analytical application. J. Biol. Chem. 180:249-261.
12. Heyns, K., and G. Kiessling. 1967. Strukturaufklarung des Vi-antigcns aus Citrobacter freundii (E. coli) 396/38. Carbohydr. Res. 3:340-353.
13. Hoare, D. G., and D. E. Koshland. 1967, A method for the quantitative modification and estimation of carboxylic acid groups in proteins. J. Biol. Chem. 22:2417-2453.
14. Inman, J. K., and H. M. Dintzis. 1969. The derivatization of cross-linked polyacrylamide beads, Controlled induction of functional groups for the purpose of special biochemical absorbents, Biochemistry 4:4074-4080.
15. Keitel, W. A., N. L. Bond, J. M. Zahradnik, T. A. Cramton, and J. B. Robbins. 1994. Clinical and serological responses following primary and booster immunization with Salmonella typhi Vi capsular polysaccharide vaccine. Vaccine 12:195-199.
16. Kenne, L., and B. Lindberg. 1981. Bacterial polysaccharides, p. 315. In G. Aspinall (ed.), The polysaccharides, vol. 2. Academic Press, Inc., New York. N.Y.
17. Klugman, K. P., H. J. Koornhof, I. T. Gilbertson, J. B. Robbins, R. Schneerson, D. Schulz, M. Cadoz, and Vaccine Advisory Committee. 1987. Protective activity of Vi capsular polysaccharide vaccine against typhoid fever. Lancet 11:1165-1169.
18. Landy, M. 1954. Studies on Vi antigen. VI. Immunization of human beings with purified Vi antigen. Am. J. Hyg. 60:52-62.
19. Landy, M. 1957. Studies on Vi antigen. VII. Characteristics of the immune response. Am. J. Hyg. 65:81-93.
20. BEN) specific for Vi capsular polysaccharidc of Salmonella typli. Infect. Immun. 63:4429-4432.
21. Peeters, C. A., A.-M. Tenbergen-Meekes, D. E. Even berg, J. T. Poolman, B. J. M. Zegers, and G. T. Rijkers. 1991. A comparative study of the immunogenicity of pneumococcal type 4 polysaccharide and oligosaccharide tetanus toxoid conjugates in adult mice. J. Immunol, 146:4308-4314.
22. Peeters, C. C. A. M., D. Evenberg, P. Hoogerhout, H. Käyhty, L. Saarinen, C. A. A. van Boeckel, G. A. van der Marel, J. H. van Boom, and J. T. Poolman. 1992. Synthetic trimer and tetramcr of 3-β-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular poiysaccharide in mice and monkeys. Infect. Immun. 60:1826-1833.
23. Plotkin, S. A., and N. Bouverest-Le Cam. 1995. A new typhoid vaccine composed of the Vi capsular poiysaccharide. Arch. Intern. Med. 155:2293-2299.
24. Polotsky, V. Y., J. B. Robbins, D. Bryla, and R. Schneerson. 1994. Comparison of conjugates composed of lipopolysaccharide from Shigella flexneri type 2a detoxified by two methods and bound to tetanus toxoid. Infect. Immun. 62:210-214.
25. Pospisil, M., J. Sandula, I. Pipalova, M. Hofer, and S. Viklicka. 1991. Hemopoiesis stimulating and radioprotective effects of earboxymethylglucan. Physiol. Res. 40:377-380.
26. Robbins, J. B., C. Y. Chu, and R. Schneerson. 1992. Hypothesis for vaccine development: protective immunity to enteric diseases caused by nontyphoidal Salmonellae and Shigellae may be conferred by serum IgG antibodies to the O-specific polysaccharide of their lipopolysaccharides. Clin. Infect. Dis. 15:346-361.
27. Robbins, J. B., R. Schneerson, and S. C. Szu. 1995. Perspective: hypothesis: serum IgG antibody is sufficient to confer protection against infectious diseases by inactivating the inoculum. J. Infect. Dis. 171:1387-1398.
28. Robbins, J. D., and J. B. Robbins. 1984. Re-examination of the immunopathogenic role of the capsular poiysaccharide (Vi antigen) of Salmonella typhi. J. Infect. Dis. 150:436-449.
29. Schneerson, R., O. Barrera, A. Sutton, and J. B. Robbins. 1980. Preparation, characterization and immunogenicity of Haemophilus influenzae type b polysaccharidc-protein conjugates. J. Exp. Med. 152:361-376.
30. Simanjuntak, C. H., N. H. Punjabi, and T. Haritining. Side effects and immune response of a parenteral ViCPS vaccine in Indonesian infants aged 6-13 months. In Program find abstracts of the Second Asia-Pacific Symposium on Typhoid Fever and Other Salmonellosis: November 7-9, 1994: Bangkok, Thailand.
31. 13C-NMR study of carboxymethyl-β-(1→6)-D-gluco-β-(1→3)-oglucan derived from Saccharo myce.1 cerevisiae. J. Appl. Polym. Sci. 48:1313-1319.
32. Steinhoff, M. C., K. Edwards, H. Keyserling, M. L. Thons, C. Jonson, D. Madore, and D. Hogermun. 1994. A randomized comparison of three bivalent Streptococcus pneumoniae glycoprotein conjugate vaccines in young children: effect of polysaccharide size and linkage characteristics. Pediatr. Infect. Dis. J. 13:368-371.
33. Szewczyk, B., and A. Taylor. 1980. Immunochemical properties of Vi antigen from Salmonella typhl Ty2: presence of two antigenic determinants. Infect. Immun. 29:539-544.
34. Szu, S. C., A. L. Stone, J. D. Robbins, R. Schneerson, and J. B. Robbins. 1987. Vi capsular polysaccharidc-protein conjugates for prevention of typhoid fever. J. Exp. Med. 166:1510-1524.
35. Szu, S. C., D. N. Taylor, A. C. Trofa, J. D. Clements, J. Shiloach, J. C. Sadoff, D. Bryla, and J. B. Robbins. 1994. Laboratory and preliminary clinical characterization of Vi capsular polysaccharide-protein conjugate vaccines. Infect. Immun, 62:4440-4444.
36. Szu, S. C., S. Bystricky, M. Hinojosa-Ahumada, W. Egan, and J. B. Robbins. 1994. Synthesis and some immunologic properties of an O-acetyl pectin [poly{l→4)α-D-GalpA]-protein conjugate as a vaccine for typhoid fever. Infect. Immun. 62:5545-5549.
37. Szu, S. C., X.-R. Li, A. L. Stone, and J. B. Robbins. 1991. Relation between structure and immunologic properties of the Vi capsular polysaccharide. Infect. Immun. 59:4555-4561.
38. Szu, S. C., C. J. Lee, D. Carlone, and J. Henrichsen. 1981. Chemical composition of and immunochemical characterization of type 9 pneumococcal polysaccharidcs. Infect. Immun. 31:371-379.
39. Szu, S. C., X. Li, R. Schneerson, J. H. Vickers, D. Bryla, and J. B. Robbins. 1989. Comparative immunogenicities of Vi polysaccharide-protein conjugates composed of cholera toxin or its B subunit as a carrier bound to highor lower-molecular-weight Vi, Infect. Immun. 57:3823-3827.
40. Wagnerova, J., A. Liskova, L. Cervenakova, T. Trnovec, and M. Ferencik. 1991. The immunoadjuvant effect of soluble glucan derivatives in mice. Folia Microbiol, 36:198-204.
41. World Health Organization Expert Committee on Biologic Standardization. 1994. Requirements for Vi polysaccharide typhoid vaccine. P9:14-33. In Technical report series 840, 43rd report. World Health Organization, Geneva. Switzerland.