Progressive increase of apoptosis in prostatic intraepithelial neoplasia and carcinoma: Comparison between in situ end-labeling of fragmented DNA and detection by routine hematoxylin-eosin staining

Archives of Pathology and Laboratory Medicine

Volumn 121, Issue 1, 1997, Pages 54-58

  Drachenberg, Cinthia B ^b   Ioffe, Olga B ^b   Papadimiriou, John C ^a  

^a UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; EOSIN; HEMATOXYLIN;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; HISTOLOGY; HUMAN; HUMAN TISSUE; MALE; MICROSCOPY; MORPHOLOGY; PROSTATE CARCINOMA; PROSTATECTOMY; PROSTATIC INTRAEPITHELIAL NEOPLASIA; STAINING; TISSUE SECTION;

EID: 0030977233     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Carter HB, Coffey DS. The prostate - an increasing medical problem. Prostate. 1990;16:39-48.
2. Gleason DF. Histologic grading and clinical staging of prostatic adenocarcinoma. In: Tannenbaum M, ed. Urologic Pathology: The Prostate. Philadelphia, Pa: Lea & Febiger; 1977:171-197.
3. Arends MJ, McGregor AH, Wyllie AH. Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras, and HPV oncogens. Am J Pathol. 1994;144(5):1045-1057.
4. Wyllie AH. Cell death: a new classification separating apoptosis from necrosis, In: Bowen ID, Lockshin RA, eds. Cell Death in Biology and Pathology. London, England: Chapman and Hall Press; 1981:9-34.
5. Steel GG, eel New York, NY: Growth Kinetics of Tumors. 1st ed. New York, NY: Clarendon Press; 1977.
6. Bursch W, Kleine L, Tenniswood M. The biochemistry of cell death by apoptosis, Biochem Cell Biol. 1990;68:1071-1074.
7. Hal PA, Levison DA. Review: assessment of cell proliferation in histological material. J Clin Pathol. 1990;43:184-192.
8. Staunton MJ, Gaffney EF. Tumor type is a determinant of' susceptibility to apoptosis. Am J Clin Pathol. 1995;103:300-307.
9. Walker PR, Kokileva L, Leblanc J, Sikorska M. Detection of the initial stages of DNA fragmentation in apoptosis, Biotechniques. 1993;15:1032-1047.
10. Brown DG, Sun XM, Cohen GM. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J Biol Chem. 1993;268:3037-3039.
11. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 1992;119:493-501.
12. Wijsman JH, Jonker RR, Keijzer R, van de Velde CJ, Cornelisse CJ, van Dierendonck JH. A new method to detect apoptosis in paraffin sections: In situ end-labeling of fragmented DNA, J Histochem Cytochem. 1993;41 (1):7-12.
13. Aihara M, Truong LD, Dunn JK, Wheeler TM, Scardino PT, Thompson TC. Frequency of apoptotic bodies positively correlates with Gleason grade in prostate cancer. Hum Pathol. 1994;25:797-801.
14. Gaffney EF. The extent of apoptosis In different types of high grade prostaitc carcinoma. Histopathology. 1994;25:269-273.
15. Aihara M, Scardino PT, Truong LD, et al. The frequency of apoptosis correlates with the prognosis of Gleason grade 3 adenocarcinoma of the prostate. Cancer. 1995;75(2):522-529.
16. Vesalainen S, Lipponen P, Talja M, Syrjanen K. Histological grade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma. Eur J Cancer. 1994;30A(12): 1797-1803.
17. Montironi R, Magi Gailuzui C, Scarpelli M, Giannulls I, Diamanti L. Occurrence of cell death (apoptosis) in prostatic intra-epithelial neoplasia. Virchows Archiv A Pathol Anat. 1993;423:351-357.
18. Wheeler TM, Rogers E, Aihara M, Scardino PT, Thompson TC. Apoptotic index as a biomarker in prostatic intraepithelial neoplasia (PIN) and prostate cancer. J Cell Biochem Suppl. 1994;19:202-207.
19. Wheeldon EB, Williams SM, Soames AR, James NH, Roberts RA. Quantitation of apoptotic bodies in rat liver by in situ end labelling (ISEL): correlation with morphology. Toxicol Pathol. 1995;23(3):410-415.
20. Drago JR, Mostofi FK. Introductory remarks and workshop summary; workshop on prostatic intraepithelial neoplasia, significance and correlation with prostate-specific antigen and transrectal ultrasound. Urology. 1989;34(suppl):2-3.
21. Fukasawa Y, Ishikura H, Takada A, et al. Massive apoptosis in infantile myofibromatosis: a putative mechanism of tumor regression. Am J Pathol. 1994;144(3):480-485.
22. Kerr JFR, Searle J, Harmon BV, Bishop CJ. Apoptosis. In: Potten CS, ed. Perspectives on Mammalian Cell Death. Oxford, England; Oxford University Press; 1987:93-128.
23. Chandler D, El-Naggar AK, Brisbay A, Redline RW, McDonnell TJ. Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: evidence for the contribution of bcl-2 expression to renal carcinogenesis. Hum Pathol. 1994;25:789-796.
24. Buttke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today, 1994;15:7-10.
25. Frisch SM, Francis H, Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol. 1994;124:619-626.
26. Pileri S, Poggi S, Sabattini E, et al. Apoptosis as programmed cell death (PCD): cupio dissolvi in cell life. Curr Diagn Pathol. 1994;1:48-55.
27. Amin MB, Ro JY, Ayala AG. Putative precursor lesions of prostatic adenocarcinoma; fact or fiction? Mod Pathol. 1993;6(4):476-483.
28. Drachenberg CB, Papadimitriou JC. Aberrant pattern of lectin binding in low and high grade prostatic intraepitheiial neoplasia, Cancer, 1995;75:2539- 2544.
29. Deschenes J, Weidner N. Nucleolar organizer regions (NOR) in hyperplastic and neoplastic prostate disease, Am J Surg Pathol. 1990;14:1148-1150.
30. Baretton CB, Vogt T, Blasenbreu S, Lohrs U. Comparison of DNA ploidy in prostatic intraepithelial neoplasia and invasive carcinomas of the prostate: an image cytomeiric study. Hum Pathol. 1994;25:506-513.
31. Sandberg AA. Chromosomal abnormalities and related events in prostate cancer, Hum Pathol. 1992;23:368-380.
32. McNeal JE, Leav I, Alroy J, Skutelsky E. Differential lectin staining of central and peripheral zones of the prostate and alterations in dysplasia. Am J Clin Pathol. 1988;89:41-48.
33. Nagle RB, Brawer MK, Kittelson J, Clark V. Phenotypic relationships of prostatic intraepithelial neoplasia to invasive prostatic carcinoma. Am J Pathol. 1991;138(1):119-128.
34. Weinberg DS, Weidmer N. The relationship between PIN and invasive prostatic carcinoma studied by static DNA cytometry. Mod Pathol. 1991;4:53A.
35. Kyprianou N, Isaacs J. Activation of programmed cell death in the rat ventral prostate after castration. Endocrinology. 1988;122:552-562.
36. Bursch W, Paffe S, Puiz B, et al. Determination of the length of the histological stages of apoptosis in normal liver and altered hepatic foci of rats. Carcinogenesis. 1990;11:847-853.
37. Collins RJ, Harmon BV, Gobe GC, Kerr JF. Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Int J Rad Biol. 1992;61:451-453.
38. Ioffe OB, Drachenberg CB, Simmons J, Papadimitriou JC. Comparison of proliferation and apoptosis indexes in benign proliferative endometrium, endometrial hyperplasia and carcinoma; higher significance of apoptosis. Lab Invest. 1996;74:91A. Abstract.