Gradation of kainic acid-induced rat limbic seizures and expression of hippocampal heat shock protein-70

European Journal of Neuroscience

Volumn 9, Issue 4, 1997, Pages 760-769

  Yu, Peter H ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Glial cell; Heat shock protein 70; Hippocampus; Immunohistochemistry; Kainic acid; Limbic seizures; Neuronal injury; Reactive astrocyte; Temporal lobe epilepsy

Indexed keywords

HEAT SHOCK PROTEIN 70; KAINIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEX PARTIAL SEIZURE; FALLING; HIPPOCAMPUS; HYPERACTIVITY; JUMPING; MALE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; WET DOG SHAKES;

EID: 0030976602     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01424.x     Document Type: Article

References (3)

1. Armstrong, T.N., Plumier, J.-C.L, Robertson, H.A. and Currie, R.W. (1996) The inducible 70,000 molecular weight heat shock protein is expressed in the degenerating dentate hilus and piriform cortex after systemic administration of kainic acid in the rat. Neuron, 74, 685-693.
2. Ben-Ari, Y. (1985) Limbic seizures and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience, 14, 375-403.
3. Ben-Ari, Y., Tremblay, E., Riche, D., Ghilini, G. and Naquet, R. (1981) Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazol: metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy. Neuron, 6, 1361-1391.