Isolation of hammerhead ribozymes with altered core sequences by in vitro selection

Biochemistry

Volumn 36, Issue 21, 1997, Pages 6495-6501

  Vaish, Narendra K ^a   Heaton, Paul A ^a   Eckstein, Fritz ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOZYME;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME ISOLATION; ENZYME SPECIFICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

BASE COMPOSITION; BASE SEQUENCE; CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RANDOM ALLOCATION; RNA, CATALYTIC; SEQUENCE DELETION; SUBSTRATE SPECIFICITY;

EID: 0030976198     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi963134r     Document Type: Article

References (27)

1. Abelson, J. N., Ed. (1996) Methods Enzymol. 267.
2. Buell, G. N., Wickens, M. P., Payvar, F., & Schimke, R. T. (1978) J. Biol. Chem. 253, 2471-2482.
3. Cariello, N. F., Thilly, W. G., Swenberg, J. A., & Skopek, T. R. (1991) Gene 99, 105-108.
4. Chapman, K. B., & Szostak, J. W. (1994) Curr. Opin. Struct. Biol. 4, 618-622.
5. Ellington, A. D., & Szostak, J. W. (1990) Nature 346, 818-822.
6. Famulok, M., & Szostak, J. W. (1993) Nucleic Acids Mol. Biol. 10, 271-284.
7. Green, I. R., & Sargan, D. R. (1991) Gene 109, 203-210.
8. Hertel, K. J., Pardi, A., Uhlenbeck, O. C., Koizumi, M., Ohtsuka, E., Uesugi, S., Cedergren, R., Eckstein, F., Gerlach, W. L., Hodgson, R., & Symons, R. H. (1992) Nucleic Acids Res. 20, 3252.
9. Igloi, G. (1988) Biochemistry 27, 3842-3849.
10. Ishizaka, M., Ohishima, Y., & Tani, T. (1995) Biochem. Biophys. Res. Commun. 214, 403-409.
11. Jucker, F. M., & Pardi, A. (1995) RNA 1, 219-222.
12. Kumar, P. K. R., & Ellington, A. D. (1995) FASEB J. 9, 1183-1195.
13. Long, D. M., & Uhlenbeck, O. C. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 6977-6981.
14. Milligan, J. F., Groebe, D. R., Witherell, G. W., & Uhlenbeck, O. C. (1987) Nucleic Acids Res. 15, 8783-8798.
15. Nakamaye, K. L., & Eckstein, F. (1994) Biochemistry 33, 1271-1277.
16. Pan, T., & Uhlenbeck, O. C. (1992) Biochemistry 31, 3887-3895.
17. Pley, H. W., Flaherty, K. M., & McKay, D. B. (1994) Nature 372, 68-74.
18. Ruffner, D. E., Stormo, G. D., & Uhlenbeck, O. C. (1990) Biochemistry 29, 10695-10702.
19. Sambrook, J., Fritsch, E. F., & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
20. Scott, W. G., Finch, J. T., & Klug, A. (1995) Cell 81, 991-1002.
21. Shimayama, T., Nishikawa, S., & Taira, K. (1995) Biochemistry 34, 3649-3654.
22. Symons, R. H. (1992) Annu. Rev. Biochem. 61, 641-671.
23. Thomson, J. B., Sigurdsson, S. T., Zeuch, A., & Eckstein, F. (1996) Nucleic Acids Res. 24, 4401-4406.
24. Tuerk, C., & Gold, L. (1990) Science 249, 505-510.
25. Tuschl, T., & Eckstein, F. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 6991-6994.
26. Williams, K. P., Ciafré, S., & Tocchini-Valentini, G. P. (1995) EMBO J. 14, 4551-4557.
27. Zoumadakis, M., & Tabler, M. (1995) Nucleic Acids Res. 23, 1192-1196.