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Volumn 53, Issue 18, 1997, Pages 6539-6554

Synthesis of 3',4'-bisphosphate-containing analogs of adenophostin A

Author keywords

[No Author keywords available]

Indexed keywords

ADENOPHOSTIN A; ADENOSINE DERIVATIVE; GLUCOSIDE; UNCLASSIFIED DRUG;

EID: 0030976059     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(97)00309-8     Document Type: Article
Times cited : (20)

References (28)
  • 24
    • 0342782483 scopus 로고    scopus 로고
    • note
    • Preliminary results indicated that NIS/TfOH-mediated glycosylation of 1,2-di-O-tert-butyldiphenylsilyl-sn-glycerol with ethyl 1-thio-α/β-D-glucopyranosyl donor 7 gave an inseparable mixture of the required product and an α-linked dimeric byproduct (15-20%). The formation of this byproduct may be explained by acid-catalyzed migration of a silyl protective group.
  • 27
    • 0343217035 scopus 로고    scopus 로고
    • note
    • In this respect, it is of interest to note that methylthiomethylation of 20 in a mixture of acetic acid/acetic anhydride/dimethyl sulfoxide gave a much lower yield (30%) in comparison with the dimethyl sulfide/BPO-mediated reaction (63%).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.