Subunit association and monomer structure of CINC/Gro revealed by 1H-NMR

Journal of Biochemistry

Volumn 121, Issue 5, 1997, Pages 835-841

  Hanzawa, Hiroyuki ^a   Haruyama, Hideyuki ^a   Konishi, Kiyoshi ^b   Watanabe, Kazuyoshi ^c   Tsurufuji, Susumu ^c  

^a DAIICHI SANKYO CO   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c Inst of Cytosignal Research Inc   (Japan)

Author keywords

Chemical shift; Equilibrium; IL 8 family; NMR

Indexed keywords

CHEMOKINE; CHEMOTACTIC FACTOR; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; DIMER; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOMER; PROTEIN SUBUNIT; SODIUM CHLORIDE;

ARTICLE; BETA CHAIN; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; ULTRACENTRIFUGATION;

EID: 0030975914     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021662     Document Type: Article

References (26)

1. Watanabe, K., Kinoshita, S., and Nakagawa, H. (1989) Purification and characterization of cytokine-induced neutrophil chemoattractant produced by epithelioid cell line of normal rat kidney (NRK-52E cell). Biochem. Biophys. Res. Commun. 161, 1093-1099
2. Watanabe, K., Konishi, K., Fujioka, M., Kinoshita, S., and Nakagawa, H. (1989) The neutrophil chemoattractant produced by rat kidney epithelioid cell line NRK-52E is a protein related to the KC/gro protein. J. Biol. Chem. 264, 19559-19563
3. Hanzawa, H., Haruyama, H., Watanabe, K., and Tsuruhuji, S. (1994) The three-dimensional structure of rat cytokine CINC/ Gro in solution by homonuclear 3D NMR. FEBS Lett. 354, 207-212
4. St. Charles, R., Walz, D.A., and Edward, B.F.P (1989) The three-dimensional structure of bovine platelet factor 4 at 3.0 Å resolution. J. Biol. Chem. 264, 2092-2099
5. Clore, B.M., Appella, E., Yamada, M., Matsushima, K., and Gronenborn, A.M. (1990) Three-dimensional structure of interleukin-8 in solution. Biochemistry 29, 1689-1696
6. Fairbrother, W.J., Reilly, D., Colby, T.J., Hesselgesser, J., and Horuk, R. (1994) The solution structure of melanoma growth stimulating activity. J. Mol. Biol. 243, 252-270
7. 1H-NMR spectroscopy. J. Biol. Chem. 269, 32909-32915
8. 1H-NMR spectroscopy. Biochemistry 28, 9469-9478
9. 1H NMR derived aggregate equilibria indicate a physiological preference for monomers over dimers and tetramers. Biochemistry 30, 925-934
10. Chen, M.J. and Mayo, K.H. (1991) Human platelet factor 4 subunit association/dissociation thermodynamics and kinetics. Biochemistry 30, 6402-6411
11. Rajarathnam, K., Sykes, B.D., Kay, C.M., Dewald, B., Geiser, T., Baggiolini, M., and Clark-Lewis, I. (1994) Neutrophil activation by monomeric interleukin-8. Science 264, 90-92
12. Burrows, S.D., Doyle, M.L., Murphy, K.P., Franklin, S.G., White, J.R., Brooks, I., McNulty, D.E., Scott, M.O., Knutson, J.R., Porter, D., Young, P.R., and Hensley, P. (1994) Determination of the monomer-dimer equilibrium of interleukin-8 reveals it is a monomer at physiological concentrations. Biochemistry 33, 12741-12745
13. Schnitzel, W., Monschein, U., and Besemer, J. (1994) Monomer-dimer equilibria of interleukin-8 and neutrophil-activating peptide 2. Evidence for IL-8 binding as a dimer and oligomer to IL-8 receptor B. J. Leuko. Biol. 55, 763-770
14. Clark-Lewis, I., Schumacher, C., Baggiolini, M., and Benhard, M. (1991) Structure-activity relationship of interleukin-8 determined using chemically synthesized analogs. J. Biol. Chem. 266, 23128-23134
15. Hebert, C.A., Vitangcol, R.V., and Baker, J.B. (1991) Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding. J. Biol. Chem. 266, 18989-18994
16. Konishi, K., Takata, Y., Watanabe, K., Date, Y., Yamamoto, M., Murase, M., Yoshida, H., Suzuki, T., Tsurufuji, S., and Fujioka, M. (1993) Recombinant expression of rat and human gro protein in Escherichia coli. Cytokine 5, 506-511
17. Glasoe, P.K. and Long, F.A. (1960) Use of glass electrodes to measure acidities in deuterium oxide. J. Phys. Chem. 64, 188-190
18. States, D.J., Habercorn, R.A., and Ruben, D.J. (1982) A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants. J. Magn. Reson. 48, 286-292
19. Bax, A. and Davis, D.G. (1985) Mlev-17-based two-dimensional homonuclear magnetization transfer spectroscopy. J. Magn. Reson. 65, 355-360
20. Jeener, J., Meier, B.H., Bachmann, P., and Ernst, R.R. (1979) Investigation of exchange process by two-dimensional NMR spectroscopy. J. Chem. Phys. 71, 4546-4553
21. Cohn, E.J. and Edsall, J.T. (1943) Proteins, Amino Acids and Peptides as Ions and Dipolar Ions, p. 157, Rheinhold, New York
22. Klotz, I.M. (1973) Physicochemical aspects of drug-protein interactions: a general perspective. Ann. N.Y. Acad. Sci. 226, 18-24
23. Ross, P.D. and Subramanian, S. (1981) Thermodynamics of protein association reactions: forces contributing to stability. Biochemistry 20, 3096-3102
24. Wishart, D.S., Sykes, B.D., and Richards, F.M. (1991) Relationship between nuclear magnetic resonance chemical shifts and protein secondary structure. J. Mol. Biol. 222, 311-333
25. Clubb, R.T., Omichinski, J.G., Clore, G.M., and Gronenborn, A.M. (1994) Mapping the binding surface of interleukin-8 complexed with an N-terminal fragment of the type 1 human interleukin receptor. FEBS Lett. 338, 93-97
26. 1H-NMR solution structure of an active monomeric interleukin 8. Biochemistry 34, 12983-12990