Biphasic kinetics of quaternary ammonium glucuronide formation from amitriptyline and diphenhydramine in human liver microsomes

Drug Metabolism and Disposition

Volumn 25, Issue 3, 1997, Pages 340-345

  Breyer Pfaff, Ursula ^a   Fischer, Dorothee ^b   Winne, Dietrich ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; DIPHENHYDRAMINE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; HISTAMINE H1 RECEPTOR ANTAGONIST; QUATERNARY AMMONIUM DERIVATIVE; TRICYCLIC ANTIDEPRESSANT AGENT; URIDINE DIPHOSPHATE GLUCURONIC ACID;

ARTICLE; DRUG CONJUGATION; DRUG GLUCURONIDATION; DRUG TRANSFORMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; PRIORITY JOURNAL;

AMITRIPTYLINE; ANTIDEPRESSIVE AGENTS, TRICYCLIC; DIPHENHYDRAMINE; ENZYME ACTIVATION; GLUCURONATES; HISTAMINE H1 ANTAGONISTS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICROSOMES, LIVER; OCTOXYNOL; QUATERNARY AMMONIUM COMPOUNDS;

EID: 0030974918     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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