A comparison of the prevalence of autoantibodies in individuals with chronic hepatitis C and those with autoimmune hepatitis: The role of interferon in the development of autoimmune diseases

Hepato-Gastroenterology

Volumn 44, Issue 14, 1997, Pages 417-425

  Bayraktar, Yusuf ^a,b   Bayraktar, Miyase ^a,b   Gurakar, Ahmet ^b   Hassanein, Tarek I ^b   Van Thiel, David H ^b  

^a HACETTEPE UNIVERSITY   (Turkey)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Autoantibodies; Autoimmune hepatitis; Hepatitis C virus; Interferon

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTINUCLEAR ANTIBODY; ANTIVIRUS AGENT; AUTOANTIBODY; INTERFERON; MICROSOME ANTIBODY; MITOCHONDRION ANTIBODY; MUSCLE ANTIBODY;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; AUTOIMMUNE HEPATITIS; AUTOIMMUNITY; COMPLICATION; CONTROLLED STUDY; DIAGNOSIS; FEMALE; HEPATITIS C; HUMAN; IMMUNE SYSTEM; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; AUTOIMMUNE DISEASES; FEMALE; HEPACIVIRUS; HEPATITIS; HEPATITIS C; HEPATITIS C ANTIBODIES; HEPATITIS, CHRONIC; HUMANS; IMMUNITY, CELLULAR; INCIDENCE; INTERFERONS; KIDNEY; MALE; MICROSOMES; MICROSOMES, LIVER; MIDDLE AGED; MITOCHONDRIA, LIVER; MUSCLE, SMOOTH; PREVALENCE; RETROSPECTIVE STUDIES; RNA, VIRAL; UP-REGULATION;

EID: 0030974854     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Iacovacci S, Sarqiacoma M, Battaqlia M, et al. Growth of hepatitis C virus in human fetal hepatocyte cell cultures [abstract]. Hepatitis C virus 1st Annual Meeting, Venezia, 1991; b5:35.
2. Hoffman R, Diepolder H, Zachoval R, et al. Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection. Gastroenterology 1995; 21(3):632-638.
3. Nakatsuji Y, Kiyosawa K, Furihata K, et al. Immunosuppressive therapy promotes the replication of hepatitis C virus followed by exacerbation of liver disease after dosage reduction or withdrawal [abstract]. Hepatology 1992; 16:215A.
4. Kiyosawa K, Sodeyama T, Tanaka E, et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis of detection of antibody to hepatitis C virus. Hepatology 1990; 12:671-675.
5. Saleh MG, Tibbs CJ, Koskinas J, et al. Hepatic and extrahepatic hepatitis C virus replication in relation to response to interferon therapy. Hepatology 1994; 20:1399-1404.
6. Romeo R, Pol S, Berthelot P, et al. Eradication of hepatitis C virus RNA after alpha-interferon therapy. Ann Intern Med 1994; 121(4):276-277.
7. Papo T, Marcellin P, Bernuau J, et al. Autoimmune chronic hepatitis exacerbated by alpha interferon. Ann Intern Med 1992; 116:51-53.
8. Magrin S, Craxi A, Fabiano C, Simonetti RG, Fiorentino G, Marino L, Diquattro O. Hepatitis C viremia in chronic liver disease: relationship to interferon-alpha or corticosteroid treatment. Hepatology 1994; 19:273-279.
9. Conlon KC, Urba WJ, Smith JW, et al. Exacerbation of autoimmune disease in patients receiving alpha-interferon therapy. Cancer 1990; 65:2237-2242.
10. Clifford BD, Donahue D, Smith L, Cable E, Luttig B, Michael M, Bonkovsky HL. High prevalence of serological markers of autoimmunity in patients with chronic hepatitis C. Hepatology 1995; 21:613-619.
11. Lenzi M, Ballardini G, Fusconi M, et al. Type 2 autoimmune hepatitis and hepatitis C virus infection. Lancet 1990; 335:258-259.
12. Magrin S, Craxi A, Fiorentina G, et al. Is autoimmune chronic hepatitis a HCV-related disease? J Hepatol 1991; 13:56-60.
13. Lunel F, Abuaf N, Frangeul L, et al. Liver/kidney microsome antibody type I and hepatitis C virus infection. Hepatology 1992; 16:630-636.
14. Magrin S, Craxi A, Fabiano C, et al. Hepatitis C virus in "autoimmune" chronic hepatitis. J Hepatol 1991; 13:364-367.
15. Lenzi M, Johnson PJ, McFarlane IG, et al. Antibodies to hepatitis C virus in autoimmune liver disease: Evidence for geographical heterogenicity. Lancet 1991; 338:277-280.
16. Michael G, Ritter A, Gerken TG, et al. Anti-GOR and hepatitis C virus in autoimmune liver diseases. Lancet 1992; 339:267-269.
17. Manns MP, Johnson EP, Griffen KF, et al. The major target antigen of liver and kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome p450dbl. J Clin Invest 1989; 83:1066-1072.
18. Manns MP, Johnson EP, Griffen KF, et al. Non-A, non-B hepatitis specific antibodies directed a host derived epitope: Implication for an autoimmune process. Lancet 1990; 336:1400-1403.
19. Mishiro S, Takeda K, Yoshikawa A, et al. An autoantibody cross-reactive to hepatitis C virus core and a host nuclear antigen. Autoimmunity 1991; 10:269-273.
20. Haddad J, Deny P, Munz-Gotheil C, et al. Lymphocytic sinladenitis of Sjögren's syndrome associated with chronic active hepatitis C virus liver disease. Lancet 1992; 339:321-323.
21. Almazio P, Provenzano G, Scimmeni M, et al. Hepatitis C virus and Sjögren's syndrome. Lancet 1992; 339-989-990.
22. Tran A, Quaranta JF, Benzaken S, et al. High prevalence of thyroid autoantibodies in a prospective series of patients with chronic hepatitis C before interferon therapy. Hepatology 1993; 18:253-257.
23. Clifford BD, Donahue D, Smith L, Cable E, Luttig B, Michael M, Bonkovsky HL. High prevalence of serological markers of autoimmunity in patients with chronic hepatitis C. Hepatology 1995; 21:613-619.
24. Fried MW, Draguesku JO, Shindo M, et al. Clinical and serological differentiation of autoimmune and hepatitis C virus related chronic hepatitis. Dig Dis Sci 1993; 38:631-636.
25. Reddy KR, Krawitt EL, Radick J, et al. Absence of LKM 1 antibody in hepatitis C viral infection in the United States [abstract]. Hepatology 1993; 18:173A.
26. Czaja AJ, Manns MP, Homburger HA. Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis. Gastroenterology 1992; 103:1290-1295.
27. Czaja AJ, Carpenter HA, Santrach PJ, et al. Evidence against hepatitis viruses as important causes of severe autoimmune hepatitis in the United States. J Hepatol 1993; 18:342-352.
28. Mitchel LS, Jetters LJ, Reddy KR, et al. Detection of hepatitis C virus antibody by first and second generation assays and polymerase chain reaction in patients with autoimmune chronic active hepatitis types I, II, and III. Am J Gastroenterol 1993; 88:1027-1034.
29. Osmond DH, Padian NS, Sheppard HW, et al. Risk factors for hepatitis C virus seropositivity in heterosexual couples. JAMA 1993; 269:361-365.
30. Maddey WC. How many types of autoimmune hepatitis are here? Gastroenterology 1993; 105:1571-1575.
31. Michel G, Ritter A, Gerken G, et al. Anti-GOR and hepatitis C virus in autoimmune liver disease. Lancet 1992; 339:267-269.
32. Lunel F, Abauf N, Franguel L, et al. Liver/kidney microsome antibody type 1 and hepatitis C virus infection. Hepatology 1992; 16:630-636.
33. Vergani D, Mieli-Vergani G. Type II autoimmune hepatitis: what is the role of the hepatitis C virus? Gastroenterology 1993; 104:1870-1873.