Histologic analysis of the lumbosacral nerve roots after compression in young and aged rabbits

Spine

Volumn 22, Issue 7, 1997, Pages 721-726

  Toh, Eiren ^a   Mochida, Joji ^a  

^a TOKAI UNIVERSITY   (Japan)

Author keywords

aging; lumbosacral nerve root; nerve compression

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; FEMALE; HISTOPATHOLOGY; LAMINECTOMY; LUMBOSACRAL PLEXUS; MALE; NERVE DEGENERATION; NERVE REGENERATION; NERVE ROOT COMPRESSION; NONHUMAN; PRIORITY JOURNAL; RABBIT;

AGE FACTORS; ANIMALS; FEMALE; LAMINECTOMY; LUMBAR VERTEBRAE; LUMBOSACRAL REGION; MALE; MICROSCOPY, ELECTRON; NERVE COMPRESSION SYNDROMES; NERVE FIBERS; RABBITS; SPINAL CANAL; SPINAL NERVE ROOTS;

EID: 0030973766     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-199704010-00001     Document Type: Article

References (21)

1. Aguayo A, Nair CPV, Midgley R. Experimental progressive compression neuropathy in the rabbit. Arch Neurol 1971; 24:358-64.
2. Cornefjord M, Olmarker K, Farley DB, Weinstein JN, Rydevik B. Neuropeptide changes in compressed spinal nerve roots. Spine 1995;20:670-3.
3. Delamarter RB, Bohlman HH, Dodge LD, Biro C. Experimental lumbar spinal stenosis: Analysis of the cortical evoked potentials, microvasculature, and histopathology. J Bone Joint Surg [Am] 1990;72:110-20.
4. Gamble HJ. Comparative electron microscopic observations on connective tissues of a peripheral nerve and a spinal nerve root in rat. J Anat 1964;98:17-25.
5. Haftek J, Thomas PK. Electron microscopic observations on the effects of localized crush injuries on the connective tissues of peripheral nerve. J Anat 1968;103:233-43.
6. Howe JF, Loeser JD, Calvin WH. Mechanosensitivity of dorsal root ganglion and chronically injured axons: A physiological basis for the radicular pain of nerve root compression. Pain 1977;3:25-41.
7. Inoue S, Takada S, Tamaki T. Low back pain and leg pain in elderly patients. Orthop Trauma Surg 1986;29:981-92.
8. Kobayashi S, Yoshizawa H, Hachiya Y, Ukai T. Pathophysiology of spinal nerve root compression. Spine Spinal Cord 1991;4:109-20.
9. Mackinnon SE, Dellon AL, Hudson AR, Hunter DA. Chronic nerve compression: an experimental model in the rat. Ann Plast Surg 1984;13:112-20.
10. Mackinnon SE, Dellon AL, Hudson AR, Hunter DA. A primate model for chronic nerve compression. J Reconstr Microsurg 1985;1:185-95.
11. Mochida J, Arima T. Clinical studies of the lumbar disc herniation in the fifties and sixties. Orthop Trauma Surg 1986; 29:665-71.
12. Murphy RW. Nerve roots and spinal nerves in degenerative disk disease. Clin Orthop 1977;129:46-60.
13. Ohama E. Some aspects of anatomy and pathology of nerve roots. Shinkei Kenkyu No Shinpo 1982;26:737-52.
14. Ohama E, Takeda S. Peculiar characteristics of nerve root edema. Shinkei Kenkyu No Shinpo 1984;28:654-9 (in Japanese).
15. Olmarker K, Rydevik B, Holm S. Edema formation in spinal nerve roots induced by experimental, graded compression: An experimental study on the pig cauda equina with special reference to differences in effects between rapid and slow onset of compression. Spine 1989;14:569-73.
16. Rydevik B, Holm S, Brown MD, Lundborg G. Diffusion from the cerebrospinal fluid as a nutritional pathway for spinal nerve roots. Acta Physiol Scand 1990;138:247-8.
17. Scham SM, Taylor TKF. Tension signs in lumbar disc prolapse. Clin Orthop 1971;75:195-204.
18. Sunderland S, Bradley KC. Stress-strain phenomena in human spinal nerve roots. Brain 1961;84:120-4.
19. Sunderland S. The connective tissues of peripheral nerves. Brain 1965;88:841-54.
20. Suzuki S, Urushidani H, Kikkawa K, et al. Lumbar disc herniation with negative Lasegue sign. Seikeigeka 1986;37: 313-7 (in Japanese).
21. Yoshizawa H, Kobayashi S, Morita T. Chronic nerve root compression: Pathophysiologic mechanism of nerve root dysfunction. Spine 1995;20:397-407.