메뉴 건너뛰기




Volumn 33, Issue 2, 1997, Pages 307-311

Phase II trial of rhIL-6 (interleukin-6) prior to and concurrently with VAD (vincristine, doxorubicin and dexamethasone) chemotherapy for patients with multiple myeloma

Author keywords

Chemotherapy; Interleukin 6; Multiple myeloma

Indexed keywords

DEXAMETHASONE; DOXORUBICIN; RECOMBINANT INTERLEUKIN 6; VINCRISTINE;

EID: 0030973669     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(96)00383-8     Document Type: Article
Times cited : (3)

References (22)
  • 1
  • 2
    • 0023849455 scopus 로고
    • Autocrine generation and essential requirement of BSF/IL-6 for human multiple myeloma
    • Kawano M, Hirano T, Matsuda T, et al. Autocrine generation and essential requirement of BSF/IL-6 for human multiple myeloma. Nature 1988, 332, 83-85.
    • (1988) Nature , vol.332 , pp. 83-85
    • Kawano, M.1    Hirano, T.2    Matsuda, T.3
  • 3
    • 0024503249 scopus 로고
    • Paracrine rather than autocrine regulation of myeloma cell growth and differentiation by interleukin-6
    • Klein B, Zhang X-G, Jourdan M, et al. Paracrine rather than autocrine regulation of myeloma cell growth and differentiation by interleukin-6. Blood 1989, 73, 517-521.
    • (1989) Blood , vol.73 , pp. 517-521
    • Klein, B.1    Zhang, X.-G.2    Jourdan, M.3
  • 4
    • 0025893903 scopus 로고
    • Simultaneous administration of granulocyte-macrophage colony-stimulating factor and cytosine arabinoside for the treatment of relapsed acute myeloid leukaemia
    • Cannistra SA, Dicarlo J, Groshek P, et al. Simultaneous administration of granulocyte-macrophage colony-stimulating factor and cytosine arabinoside for the treatment of relapsed acute myeloid leukaemia. Leukaemia 1991, 5, 230-238.
    • (1991) Leukaemia , vol.5 , pp. 230-238
    • Cannistra, S.A.1    Dicarlo, J.2    Groshek, P.3
  • 5
    • 0024834136 scopus 로고
    • Fluorouracil and recombinant alfa-2a interferon: An active regimen against advanced colorectal carcinoma
    • Wadler S, Schwartz EL, Goldman M, et al. Fluorouracil and recombinant alfa-2a interferon: an active regimen against advanced colorectal carcinoma. J Clin Oncol 1989, 7, 1769-1775.
    • (1989) J Clin Oncol , vol.7 , pp. 1769-1775
    • Wadler, S.1    Schwartz, E.L.2    Goldman, M.3
  • 6
    • 0029147155 scopus 로고
    • Toxicity and efficacy of escalating dosages of recombinant human IL-6 after chemotherapy in patients with breast cancer or non-small cell lung cancer
    • Veldhuis GJ, Willemse PH, Sleijfer DT, et al. Toxicity and efficacy of escalating dosages of recombinant human IL-6 after chemotherapy in patients with breast cancer or non-small cell lung cancer. J Clin Oncol 1995, 13, 2585-2593.
    • (1995) J Clin Oncol , vol.13 , pp. 2585-2593
    • Veldhuis, G.J.1    Willemse, P.H.2    Sleijfer, D.T.3
  • 7
    • 0029003110 scopus 로고
    • Phase I multicentre trial of interleukin-6 therapy after autologous bone marrow transplantation in advanced breast cancer
    • Lazarus HM, Winton EF, Williams SF, et al. Phase I multicentre trial of interleukin-6 therapy after autologous bone marrow transplantation in advanced breast cancer. Bone Marrow Transplant 1995, 15, 935-942.
    • (1995) Bone Marrow Transplant , vol.15 , pp. 935-942
    • Lazarus, H.M.1    Winton, E.F.2    Williams, S.F.3
  • 8
    • 0029075385 scopus 로고
    • A phase I trial of recombinant II-6 in patients with myelodysplastic syndromes and thrombocytopenia
    • Gordon MS, Nemunaitis J, Hoffman R, et al. A phase I trial of recombinant II-6 in patients with myelodysplastic syndromes and thrombocytopenia. Blood 1995, 85, 3066-3076.
    • (1995) Blood , vol.85 , pp. 3066-3076
    • Gordon, M.S.1    Nemunaitis, J.2    Hoffman, R.3
  • 9
    • 0028153776 scopus 로고
    • Immune function of patients receiving recombinant human IL-6 in a phase I clinical study: Induction of C-reactive protein and IgE and inhibition of natural killer and LAK cell activity
    • Scheid C, Young R, McDermott R, Fitzsimmons L, Scarffe JH, Stern PL. Immune function of patients receiving recombinant human IL-6 in a phase I clinical study: induction of C-reactive protein and IgE and inhibition of natural killer and LAK cell activity. Cancer Immunol Immunother 1994, 38, 119-126.
    • (1994) Cancer Immunol Immunother , vol.38 , pp. 119-126
    • Scheid, C.1    Young, R.2    McDermott, R.3    Fitzsimmons, L.4    Scarffe, J.H.5    Stern, P.L.6
  • 10
    • 0027978341 scopus 로고
    • Effects of human IL-6 in cancer patients: A phase I-II study
    • van Gameren MM, Willemse PH, Mulder PH, et al. Effects of human IL-6 in cancer patients: a phase I-II study. Blood 1994, 84, 1434-1441.
    • (1994) Blood , vol.84 , pp. 1434-1441
    • Van Gameren, M.M.1    Willemse, P.H.2    Mulder, P.H.3
  • 11
    • 0029144947 scopus 로고
    • Phase II study of IL-6 in patients with smouldering relapse of acute myelogenous leukaemia
    • Estey E, Andreeff M. Phase II study of IL-6 in patients with smouldering relapse of acute myelogenous leukaemia. Leukaemia 1995, 9, 1440-1443.
    • (1995) Leukaemia , vol.9 , pp. 1440-1443
    • Estey, E.1    Andreeff, M.2
  • 12
    • 0021322023 scopus 로고
    • Effective treatment of advanced multiple myeloma refractory to alkylating agents
    • Barlogie B, Smith L, Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. N Engl J Med 1984, 310, 1353-1356.
    • (1984) N Engl J Med , vol.310 , pp. 1353-1356
    • Barlogie, B.1    Smith, L.2    Alexanian, R.3
  • 13
    • 0028872645 scopus 로고
    • VAD chemotherapy as remission induction for multiple myeloma
    • Anderson H, Scarffe JH, Ranson M, et al. VAD chemotherapy as remission induction for multiple myeloma. Br J Cancer 1995, 71, 326-330.
    • (1995) Br J Cancer , vol.71 , pp. 326-330
    • Anderson, H.1    Scarffe, J.H.2    Ranson, M.3
  • 14
    • 0016804136 scopus 로고
    • A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment and survival
    • Durie BGM, Salmon SE. A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment and survival. Cancer 1975, 36, 842-854.
    • (1975) Cancer , vol.36 , pp. 842-854
    • Durie, B.G.M.1    Salmon, S.E.2
  • 15
    • 0001292684 scopus 로고
    • Proposed guide-lines for protocol studies II. Plasma cell myeloma
    • Chronic Leukaemia Task Force. Proposed guide-lines for protocol studies II. Plasma cell myeloma. Cancer Chemother Rep 1973, 4, 145-157.
    • (1973) Cancer Chemother Rep , vol.4 , pp. 145-157
  • 16
    • 0024350166 scopus 로고
    • Intensive treatment of multiple myeloma and criteria for complete remission
    • Gore ME, Viner C, Meldrum M, et al. Intensive treatment of multiple myeloma and criteria for complete remission. Lancet 1989, ii, 879-885.
    • (1989) Lancet , vol.2 , pp. 879-885
    • Gore, M.E.1    Viner, C.2    Meldrum, M.3
  • 17
    • 0029096426 scopus 로고
    • Recombinant human IL-6 induces a rapid and reversible anaemia in cancer patients
    • Nicken J, Mulder NH, Buter J, et al. Recombinant human IL-6 induces a rapid and reversible anaemia in cancer patients. Blood 1995, 86, 900-905.
    • (1995) Blood , vol.86 , pp. 900-905
    • Nicken, J.1    Mulder, N.H.2    Buter, J.3
  • 18
    • 0029112458 scopus 로고
    • IL-6 associated anaemia: Determination of the underlying mechanism
    • Atkins MB, Kappler K, Mier JW, Isaacs RE, Berkman EM. IL-6 associated anaemia: determination of the underlying mechanism. Blood 1995, 86, 1288-1291.
    • (1995) Blood , vol.86 , pp. 1288-1291
    • Atkins, M.B.1    Kappler, K.2    Mier, J.W.3    Isaacs, R.E.4    Berkman, E.M.5
  • 19
    • 0024832002 scopus 로고
    • Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias
    • Bataille R, Jourdan M, Zhang X-G, Klein R. Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias. J Clin Invest 1989, 84, 2008-2011.
    • (1989) J Clin Invest , vol.84 , pp. 2008-2011
    • Bataille, R.1    Jourdan, M.2    Zhang, X.-G.3    Klein, R.4
  • 20
    • 0028952405 scopus 로고
    • Immunoreactive interleukin-6 and acute phase proteins as prognostic factors in multiple myeloma
    • Pelliniemi T-T, Irjala K, Mattila K, et al. Immunoreactive interleukin-6 and acute phase proteins as prognostic factors in multiple myeloma. Blood 1995, 85, 765-771.
    • (1995) Blood , vol.85 , pp. 765-771
    • Pelliniemi, T.-T.1    Irjala, K.2    Mattila, K.3
  • 21
    • 0024337602 scopus 로고
    • BSF-2/IL-6 does not augment Ig secretion but stimulates proliferation in myeloma cells
    • Tanabe O, Kawano M, Tanaka H, et al. BSF-2/IL-6 does not augment Ig secretion but stimulates proliferation in myeloma cells. Am J Haematol 1989, 31, 258-262.
    • (1989) Am J Haematol , vol.31 , pp. 258-262
    • Tanabe, O.1    Kawano, M.2    Tanaka, H.3
  • 22
    • 0023706101 scopus 로고
    • Separation of human myeloma cells from bone marrow aspirates in multiple myeloma and their proliferation and M-protein secretion in vitro
    • Iwato K, Kawano M, Asaoku H, et al. Separation of human myeloma cells from bone marrow aspirates in multiple myeloma and their proliferation and M-protein secretion in vitro. Blood 1988, 72, 562-566.
    • (1988) Blood , vol.72 , pp. 562-566
    • Iwato, K.1    Kawano, M.2    Asaoku, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.