Activation of inwardly rectifying potassium channeIs by muscarinic receptor-linked G protein in isolated human ventricular myocytes

Journal of Membrane Biology

Volumn 157, Issue 1, 1997, Pages 71-81

  Koumi, S I ^a,b   Sato, R ^a,c   Nagasawa, K ^b   Hayakawa, H ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

G proteins; Human ventricular myocytes; Inwardly rectifying; K+ channel; Muscarinic K+ channel; Patch clamp technique

Indexed keywords

ACETYLCHOLINE; ATROPINE; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC RECEPTOR; PERTUSSIS TOXIN; POTASSIUM CHANNEL;

ARTICLE; CONTROLLED STUDY; HEART VENTRICLE WALL; HUMAN; HUMAN CELL; ION CONDUCTANCE; MEMBRANE CURRENT; MUSCLE CELL; PATCH CLAMP;

CELLS, CULTURED; GTP-BINDING PROTEINS; HEART VENTRICLES; HUMANS; ION CHANNEL GATING; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RECEPTORS, MUSCARINIC;

EID: 0030973496     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900217     Document Type: Article

References (40)

1. Allen, D.G., Morris, P.G., Orchard, C.H., Pirolo, J.S. 1985. A nuclear magnetic resonance study of metabolism in the ferret heart during hypoxia and inhibition of glycolysis. J. Physiol. 361:185-204
2. Balser, J.R., Roden, D.M., Bennett, P.B. 1991. Single inward rectifier potassium channels in guinea pig ventricular myocytes: effects of quinidine. Biophys J. 59:150-161
3. Boyett, M.R., Kirby, M.S., Orchard, C.H., Roberts, A. 1988. The negative inotropic effect of acetylcholine on ferret ventricular myocardium. J. Physiol. 404:613-635
4. Breitwieser, G.E., Szabo, G. 1985. Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue. Nature 317:538-540
5. Colquhoun, D., Hawkes, A.G. 1981. On the stochastic properties of single ion channels. Proc. R. Soc. Lond. B. 211:205-235
6. Colquhoun, D., Hawkes, A.G. 1983. The principles of the stochastic interpretation of ion-channel mechanisms. In: Single-Channel Recording. B. Sakmann and E. Neher, editors. pp. 135-175, Plenum Publishing, New York
7. Colquhoun, D., Sigworth, F.J. (1983. Fitting and statistical analysis of single-channel records. In: Single-Channel Recording, B. Sakmann and E. Neher, editors, pp. 191-263, Plenum Publishing, New York
8. Elliott, A.C., Smith, G.L., Allen, D.G. 1989. Simultaneous measurements of action potential duration and intracellular ATP in isolated ferret hearts exposed to cyanide. Circ. Res. 64:583-591
9. Fleming, J.W., Wisler, P.L., Watanabe, A.M. 1992. Signal transduction by G proteins in cardiac tissues. Circulation 85:420-433
10. + channels in insulinoma cells via a G protein. FEBS Lett. 242:94-96
11. Hamill, O.P., Marty, A., Neher, E., Sakmann, B., Sigworth, F.J. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pfluegers Arch. 391:85-100
12. Hartzell, H.C., Simmons, M.A. 1987. Comparison of effects of acetylcholine on calcium and potassium currents in frog atrium and ventricle. J. Physiol. 389:411-422
13. + channel activity in guinea-pig atrial cells is supported by nucleoside diphosphate kinase. Pfluegers Arch. 422:316-324
14. Heidbuchel, H., Vereecke, J., Carmeliet, E. 1990. Three differenct potassium channels in human atrium. Contribution to the basal potassium conductance. Circ. Res. 66:1277-1286
15. Hino, N., Ochi, R. 1980. Effect of acetylcholine on membrane currents in guinea-pig papillary muscle. J Physiol. 307:183-197
16. Isenberg, G., U. Klockner. 1982. Calcium tolerant ventricular myocytes prepared by preincubation in KB medium. Pfluegers ARch. 395:6-18
17. Josephson, I., Sperelakis, N. 1982. On the ionic mechanism underlying adrenergic-cholinergic antagonism in ventricular muscle. J. Gen. Physiol 79:69-86
18. Kitakaze, M., Hori, M., Kamada, T. 1993. Role of adenosine and its interaction with alpha adrenoceptor activity in ischaemic and reperfusion injury of the myocardium. Cardiovasc. Res. 27:18-27
19. + channel response to acetylcholine and to G protein-mediated activation in atrial myocytes isolated from failing human hearts. Circulation 90:2213-2224
20. + channel in human cardiac myocytes: Alterations in channel behavior in myocytes isolated from patients with idiopathic dilated cardiomyopathy. Circulation 92:164-174
21. Koumi, S-i., Backer, C.L., Arentzen, C.E., Sato, R. 1995b. β-Adrenergic modulation of the inwardly-rectifying potassium channel in isolated human ventricular myocytes: Alteration in channel response to β-adrenergic stimulation in failing human hearts. J. Clin. Invest. 96:2870-2881
22. Kurachi, Y. 1995. G protein regulation of cardiac muscarinic potassium channel. Am. J. Physiol. 269:C821-C830
23. + channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins. Pfluegers Arch. 407:264-274
24. Loffelholz, K., Pappano, A.J. 1985. The parasympathetic neuroeffector junction of the heart. Pharmacol Rev. 37:1-24
25. Martin, J.M., Subers, E.M., Halvorsen, S.W., Nathanson, N.M. 1987. Functional and physical properties of chick atrial and ventricular GTP-binding proteins: Relationship to muscarinic acetylcholine receptor-mediated responses. J. Pharmacol. Exp. Ther. 240:683-688
26. McMorn, S.O., Harrison, S.M., Zang, W.J., Yu, X.J., Boyett, M.R. 1993. A direct negative inotropic effect f acetylcholine on rat ventricular myocytes. Am. J. Physiol. 265:H1393-H1400
27. Mitra R, Morad M. 1985. A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates. Am. J. Physiol. 249:H1056-H1060
28. Narahashi, T., Tsunoo, A., Yoshii, M. 1987. Characterization of two types of calcium channels in moust neuroblastoma cells. J. Physiol 383:231-249
29. Nichols, C.G., Lederer, W.J. 1991. Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. Am. J. Physiol. 261:H1675-H1686
30. Noma, A., Shibasaki, T. 1985. Membrane current through adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells. J. Physiol. 363:463-480
31. Pfaffinger, P.J., Martin, J.M., Hunter, D.D., Nathanson, N.M., Hille, B. 1985. GTP-binding proteins couple cardiac muscarinic receptors to a K channel. Nature 317:536-538
32. Prystowsky, E.N., Jackman, W.M., Rinkenberger, R.L., Heger, J.J., Zipes, D.P. 1981. Effect of autonomic blockade on ventricular refractoriness and atrioventricular nodal conduction in man: Evidence supporting a direct cholinergic action on ventricular muscle refractoriness. Circ. Res. 49:511-518
33. Robishaw, J.D., Foster, K.A. 1989. Role of G proteins in the regulation of the cardiovascular system. Annu. Rev. Physiol. 51:229-244
34. Sakmann, B., Trube, G. 1984a. Voltage-dependent inactivation of inward-rectifying single-channel currents in the guinea-pig heart cell membrane. J. Physiol. 347:659-683
35. Sakmann, B., Trube, G. 1984b. Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea-pig heart. J. Physiol. 347:641-657
36. Sato, R., Hisatome, I., Wasserstrom, J.A., Arentzen, C.E., Singer, D.H. 1990. Acetylcholine-sensitive potassium channels in human atrial myocytes. Am. J. Physiol. 259:H1730-H1735
37. Soejima, M., Noma, A. 1984. Mode of regulation of the ACh-sensitive K channel by the muscarinic receptor in rabbit atrial cells. Pfluegers Arch. 400:424-431
38. Trube, G., Hescheler, J. 1984. Inward-rectifying channels in isolated patches of the heart cell membrane: ATP-dependent and comparison with cell-attached patches. Pfluegers Arch. 401:178-184
39. Wess, J. 1993. Mutational analysis of muscarinic acetylcholine receptors: structural basis of ligand/receptor/G protein interactions. Life Sciences 53:1447-1463
40. Zang, W.J., Yu, X.J., Honjo, H., Kirby, M.S., Boyett, M.R. 1993. On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells. J. Physiol. 464:649-679