New directions in breast cancer research

FASEB Journal

Volumn 11, Issue 7, 1997, Pages 535-543

  Wolman, Sandra R ^a,d   Heppner, Gloria H ^b   Wolman, Eric ^c  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c George Mason University   (United States)

^d NONE   (United States)

Author keywords

Cellular models for preneoplastic disease; Chemoprevetion; Hormonal risk; Molecular genetics; Tumor environment

Indexed keywords

ANGIOGENESIS; BREAST CANCER; BREAST CARCINOGENESIS; CANCER PREVENTION; CANCER RESEARCH; CANCER SUSCEPTIBILITY; GENE ISOLATION; GENE MUTATION; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; HUMAN; MALIGNANT TRANSFORMATION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; REVIEW; TUMOR VASCULARIZATION;

MUS MUSCULUS;

EID: 0030972755     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.11.7.9212077     Document Type: Review

References (47)

1. Hall, J. M., Lee, M. K., Newman, B., et al. (1990) Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250, 1684-1689
2. Miki, Y., Swensen, J., Shattuck-Eidens, D., et al. (1994) A strong candidate for the breast and breast-ovarian cancer susceptibility gene BRCA1. Science 266, 66-71
3. Wooster, R., Bignell, G., Lancaster, J., et al. (1995) Identification of the breast cancer susceptibility gene BRCA2. Nature (London) 378, 789-792
4. Marcus, J. N., Watson, P., Page, D. L., et al. (1996) Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage. Cancer 77, 697-709
5. Swift, M., Morrell, D., Massey, R. B., et al. (1991) Incidence of cancer in 161 families affected by ataxia-telangiectasia. N. Engl. J. Med. 325, 1831-1836
6. Narod, S. (1993) Hereditary breast-ovarian cancer: How can we use the new DNA markers to improve patient management? Clin. Invest. Med. 16, 314-317
7. Phelan, C. M., Lancaster, J. M., Tonin, P., et al. (1996) Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families. Nature Genet. 13, 120-122
8. Sheng, Z. M., Guerin, M., Gabillot, M., et al. (1988) C-Ha-ras-1 polymorphism in human breast carcinomas: evidence for a normal distribution of alleles. Oncogene Res. 2, 245-250
9. Phelan, C. M., Rebbeck, T. R., Weber, B. L., et al. (1996) Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus. Nature Genet. 12, 309-311
10. Cropp, S. C., Nevanlinna, H. A., Pyrhoonen, S., et al. (1994) Evidence of involvement of BRCA1 in sporadic breast carcinomas. Cancer Res. 54, 2548-2551
11. Wolman, S. R., and Visscher, D. (1993) Cellular genetic alterations in breast and colon cancer. In Biology of the Cancer Cell, Vol. 11, Advances in Molecular and Cell Biology, Vol. 7 (Heppner, G. H., ed) pp. 1-34, JAI Press, New York
12. 3H mice. Cancer Res. 19, 515-520
13. Medina, D. Preneoplasia in mammary tumorigenesis. (1996) In Mammary Tumor Cell Cycle, Differentiation and Metastasis (Dickson, R. B., Lippman, M. E., eds) pp. 36-69, Kluwer Academic, Boston
14. Ammundadottir, L. T., Merlino, G., and Dickson R. B. (1996) Transgenic mouse models of breast cancer. Breast Cancer Res. Treat. 39, 119-135
15. Cardiff, R. D. (1996) The biology of mammary transgenes: five rules. J. Mammary Gland Biol. Neoplasia 1, 61-73
16. Page, D. L., and Anderson, T. J. (1987) Diagnostic Histopathology of the Breast, pp. 120-145, Churchill Livingstone, Edinburgh, U.K.
17. Dawson, P. J., Wolman, S. R., Tait, L., Heppner, G. H., and Miller, F. R. (1996) MCF10AT: A model for the evolution of cancer from proliferative breast disease. Am. J. Pathol. 148, 313-319
18. Soule, H. D., Maloney, T. M., Wolman, S. R., et al. (1990) Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res. 50, 6075-6086
19. Tait, L., Dawson, P. J., Wolman, S. R., Galea, K., and Miller, F. R. (1996) Multipotent human breast stem cell line MCF10AT. Int. J. Oncol. 9, 263-267
20. Shekhar, P. V. M., Chen, M.-L., Werdell, J., et al. (1995) Activation of the estrogen receptor (ER) gene in MCF10AneoT cells, a potential factor in neoplastic progression of MCF10AT xenografts. Proc. Am. Assoc. Cancer Res. 36, 1523
21. Shekhar, P. V. M., Christman, J. K., Chen, M.-L., Jones, R. F., and Werdell, J. (1996) Altered p53 conformation in neoplastic progression of MCF10AneoT xenograft model. Proc. Am. Assoc. Cancer Res. 37, 4026
22. Inavani, S., Dawson, P. J., and Miller, F. R. (1996) Tumor histotype and gene expression in the MCF10AT model. FASEB J. 10, 2406 (abstr.)
23. Clark, G. J., Kinch, M. S., Gilmer, T. M., Burridge, K., and Der, C. J. (1996) Overexpression of the Ras-related TC21/R-Ras2 protein may contribute to the development of human breast cancers. Oncogene 12, 169-176
24. Miller, F. R., Pauley, R. J., and Wang, B. (1996) Mutated H-ras is not sufficient to produce the preneoplastic phenotype of human breast stem cell line MCF10AT. Proc. Am. Assoc. Cancer Res. 37, 3879
25. Bissell, M. J., and Aggeler, J. (1987) Dynamic reciprocity: how do extracellular matrix and hormones direct gene expression? In Mechanisms of Signal Transduction by Hormones and Growth Factors (Cabot, M. C., McKeehan, W. L., eds) pp. 251-262, Liss, New York
26. Singer, C., Rasmussen, A., Smith, H. S., et al. (1995) Malignant breast epithelium selects for insulin-like growth factor II expression in breast stroma: evidence for paracrine function. Cancer Res. 55, 2448-2454
27. Rønnov-Jessen, L., Petersen, O. W., and Bissell, M. J. (1996) Cellular changes involved in conversion of normal to malignant breast: Importance of the stromal reaction. Physiol. Rev. 76, 69-125
28. Holmgren, L., O'Reilly, M. S., and Folkman, J. (1995) Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nature Med. 1, 149-153
29. O'Reilly, M. S., Holmgren, L., Shing, Y., et al. (1994) Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315-328
30. Dvorak, H. F., Sioussat, T. M., Brown, L. F., et al. (1991) Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. J. Exp. Med. 174, 1275-1278
31. Chen, C., Parangi, S., Tolentino, M. J., and Folkman, J. (1995) A strategy to discover circulating angiogenesis inhibitors generated by human tumors. Cancer Res. 55, 4230-4233
32. Chambers, A. F., MacDonald, I. C., Schmidt, E. E., et al. (1995) Steps in tumor metastasis: new concepts from intravital videomicroscopy. Cancer Metastasis Rev. 14, 279-301
33. O'Reilly, M. S., Holmgren, L., Chen, C., and Folkman, J. (1996) Angiostatin induces dormancy of human primary tumors in mice. Nature Med. 2, 689-692
34. Key, T. J. A., and Pike, M. C. (1988) The role of oestrogens and progestagens in the epidemiology and prevention of breast cancer. Eur. J. Cancer Clin. Oncol. 24, 29-43
35. Pike, M. C., Spicer, D. V., Dahmoush, L., and Press, M. F. (1993) Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk. Epidemiol. Rev. 15, 17-35
36. Kvåle, G. (1992) Reproductive factors in breast cancer epidemiology. Acta Oncol. 31, 187-194
37. Colditz, G. A., Hankinson, S. E., Hunter, D. J., et al. (1995) The use of estrogens and progestins and the risk of breast cancer in postmenopausal women. N. Engl. J. Med. 332, 1589-1593
38. Kelsey, J. L. (1993) Breast cancer epidemiology: summary and future directions. Epidemiol. Rev. 15, 256-263
39. Brinton, L. A., and Schairer, C. (1993) Estrogen replacement therapy and breast cancer risk. Epidemiol. Rev. 15, 66-79
40. Brinton, L. A., Daling, J. R., Liff, J. M., et al. (1995) Oral contraceptives and breast cancer risk among younger women. J. Natl. Cancer Inst. 87, 827-835
41. Ziegler, R. G., Hoover, R. N., Nomura, A. M. Y., et al. (1996) Relative weight, weight change, height, and breast cancer risk in Asian-American women. J. Natl. Cancer Inst. 88, 650-660
42. Russo, J., and Russo, I. H. (1994) Toward a physiological approach to breast cancer prevention. Cancer Epidemiol. Biomark. Prevent. 3, 353-364
43. Pike, M. C. (1987) Age-related factors in cancers of the breast, ovary, and endometrium. J. Chron. Dis. 40 (Suppl. 2), 59S-69S
44. Spicer, D. V., Krecker, E. A., and Pike, M. C. (1995) The endocrine prevention of breast cancer. Cancer Invest. 13, 495-504
45. Whelan, E. A., Sandler, D. P., Root, J. L., Smith, K. R., and Weinberg, C. R. (1994) Menstrual cycle patterns and risk of breast cancer. Am. J. Epidemiol. 140, 1081-1090
46. Cauley, J. A., Lucas, F. L., Kuller, L. H., et al. (1996) Bone mineral density and risk of breast cancer in older women. J. Am. Med. Assoc. 276, 1404-1408
47. Rosner, B., Colditz, G. A., and Willett, W. C. (1994) Reproductive risk factors in a prospective study of breast cancer: the Nurses' Health Study. Am. J. Epidemiol. 139, 819-835