Glucocorticoid modulation of muscarinic and β-adrenergic receptors in guinea pig lung

Fundamental and Clinical Pharmacology

Volumn 11, Issue 2, 1997, Pages 111-116

  Scherrer, D ^a   Lach, E ^a   Landry, Y ^a   Gies, J P ^a  

^a INSERM   (France)

Author keywords

glucocorticoid; guinea pig lung; muscarinic receptors; adrenergic receptors

Indexed keywords

BETA ADRENERGIC RECEPTOR; CARBACHOL; DIHYDROALPRENOLOL; GLUCOCORTICOID; METHYLPREDNISOLONE; METHYLSCOPOLAMINE; MUSCARINIC RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; DRUG RECEPTOR BINDING; GUINEA PIG; ISOTOPE LABELING; LUNG PARENCHYMA; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030972306     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.1997.tb00176.x     Document Type: Article

References (26)

1. Barnes PJ. Beta-adrenergic receptors and their regulation. Am J Respir Crit Care Med 1995;152:838-60
2. Barnes PJ, Jacobs MM, Roberts JM. Glucocorticoids preferably increase fetal alveolar beta-receptors; autoradiographic evidence. 1984;18:1191-4
3. Boschetto P, Rogers DF, Fabbri L, Barnes PJ. Corticosteroid inhibition of airway microvascular leakage. Am Rev Respir Dis 1991;143:605-9
4. Caulfield MP. Muscarinic receptors, characterization, coupling and function. Pharmacol Ther 1993;58:319-79
5. 2-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids. J Biol Chem 1988;263:9067-70
6. Davis AO, Lefkovitz RJ. Regulation of beta-adrenergic receptors by steroid hormones. Ann Rev Physiol 1984;46:119-30
7. 2-adrenergic receptor: expression and promoter characterization. Proc Natl Acad Sci USA 1987;84:6695-9
8. Fraser CM, Venter JC. The synthesis of beta-adrenergic receptors in cultured human lung cells: induction by glucocorticoids. Biochem Biophys Res Comm 1980;94:390-7
9. Gies JP, Bertrand C, Vanderheyden P, Waeldele F, Dumont P, Pauli G, Landry Y. Characterization of muscarinic receptors in human, guinea pig and rat lung. J Pharmacol Exp Ther 1989;250:309-15
10. Guyre PM, Girard MT, Morgorelli PM, Maginiello PD. Glucocorticoid effects on the production and action of immune cytokines. J Steroid Chem 1988;30:89-93
11. Hadcock JR, Williams DL, Malbon CC. Physiological regulation at the level of rnRNA: analysis of the steady state levels of specific mRNA by DNA-excess solution hybridization. Am J Physiol 1989;256:C457-65
12. Haddad EB, Landry Y, Gies JP. Muscarinic receptor subtypes in guinea-pig airway. Am J Physiol 1991;261: L327-33
13. 3H]4-DAMP binding. Pulmon Pharmacol 1993;6:119-27
14. Hulme EC, Birdsall NJM, Buckley NJ. Muscarinic receptor subtypes. Annu Rev Pharmacol Toxicol 1990;30:633-73
15. 2-adrenergic and their promoter agonists. J Biol Chem 1987:262:7321-7
16. 2-adrenergic receptor transcription in human lung. Am J Physiol 1995a;12:L41-6
17. 2-adrenergic receptors in vivo. J Clin Invest 1995b;96:99-106
18. 2-adrenergic receptor gene are obligative for glucocorticoid regulation of hamster mRNA levels. Biochem Biophys Res Commun 1988;154:676-81
19. Mano KA, Akbarzadeh RG, Townley RG. Effect of hydrocortisone on beta-receptors in lung membranes. Life Sci 1979; 25:1925-30
20. Marquadt DL, Moyulsky HJ, Wasserman SI. Rat lung cholinergic receptor: characterization and regulation by glucocorticoids. J Appl Physiol 1982;53:731-6
21. Munson J, Rodbard D. Ligand: a versatile computerized approach to characterization of ligand-binding systems. Anal Biochem 1980;107:220-39
22. Nabishah BM, Morat BM, Kadir BA, Khalid BAK. Effect of steroid hormones on muscarinic receptors of bronchial smooth muscle. Gen Pharmacol 1991;22:389-92
23. Pretolani M, Vargaftig BB. From lung hypersensitivity to bronchial hyperreactivity. What can we learn from studies on animal models? Biochem Pharmacol 1993;45: 791-800
24. Schleimer RP, Undem BJ, Meeker S. Dexamethasone inhibits the antigen-induced contractile activity and release of inflammatory mediators in isolated guinea pig lung tissue. Am Rev Respir Dis 1987;135:562-6
25. Shimura S, Sasaki T, Ikeda K, Sasaki H, Takishima T. Direct inhibitory action of glucocorticoids or glycoconjugate secretion from airway submucosal glands. Am Rev Respir Dis 1989;141:1044-9
26. Tattersfield AE. Effect of beta-agonists and anticholinergic drugs on bronchial reactivity. Am Rev Respir Dis 1987;136: S64-8