Lipolytic catecholamine resistance linked to α2-adrenoceptor sensitivity - A metabolic predictor of weight loss in obese subjects

International Journal of Obesity

Volumn 21, Issue 4, 1997, Pages 314-320

  Hellstrom L ^a   Rossner S ^a   Hagstrom Toft E ^a   Reynisdottir, S ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Adipocyte; Adrenoceptors; Human; Hypocaloric diet; Noradrenaline

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CATECHOLAMINE; CLONIDINE; GLYCEROL; LIPID; NORADRENALIN;

ADULT; ARTICLE; BIOPSY; BODY WEIGHT; CLINICAL ARTICLE; FEMALE; HUMAN; LIPOLYSIS; LOW CALORY DIET; OBESITY; PRIORITY JOURNAL; SUBCUTANEOUS FAT; WEIGHT REDUCTION;

EID: 0030972291     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0800407     Document Type: Article

References (18)

1. Wadden TA, Stunkard AJ, Brownell KD. Very low calorie diets: Their efficacy, safety and future. Ann Intern Med 1983; 99: 675-684.
2. Astrup A, Buemann B, Gluud C, Bennet P, Tjur T, Christensen N. Prognostic markers for diet-induced weight loss in obese women. Int J Obes 1995; 19: 275-278.
3. Thomas PR. Criteria for evaluating weight-management programs. In: Thomas PR (ed). Weighing the Options. National Academy Press: Washington DC, 1995, pp 118-134.
4. Coppack S, Jensen MD, Miles JM. In vivo regulation of lipolysis in humans. J Lipid Res 1994; 35: 177-193.
5. Lafontan M, Berlan M. Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res 1993; 34: 1057-1092.
6. 3-adrenoceptor: an update. Eur J Endocrinol 1995; 132: 377-385.
7. Rozen R, Banegas E, Davilla M, Apfelbaum M. Effects of a very-low-calorie diet on adrenergic responsiveness in human adipose tissue. Int J Obes 1984; 8: 141-149.
8. Pedersen O, Hjöllund E, Schwartz Sörensen N. Insulin receptor binding and insulin action in human fat cells: effects of obesity and fasting. Metabolism 1982; 32: 884-895.
9. Hellström L, Reynisdottir S, Langin D, Rössner S, Arner P. Regulation of lipolysis in fat cells of obese women during long-term hypocaloric diet. Int J Obes 1996; 20: 745-752.
10. Kolacynski JW, Morales LM, Moore JH, Considine RV, Pierrzkowski Z, Noto PF, Colberg J, Caro J. A new technique for biopsy of human abdominal fat under local anaesthesia with lidocaine. Int J Obes 1994; 18: 161-166.
11. Rodbell M. Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem 1964; 239: 375-280.
12. 2-adrenoceptor expression in fat cells. J Clin Invest 1992; 90: 2175-2186.
13. Hellmér J, Arner P, Lundin A. Automatic luminometric kinetic assay of glycerol for lipolysis studies. Anal Biochem 1989; 177: 132-137.
14. Wadden TA, Bell SJ. Obesity. In: Bellack AS, Hersen M, Kazdin AE (eds). International Handbook of Behaviour Modification and Therapy, 2nd edn. Plenum Press: New York, 1990, pp 449-473.
15. Wadden TA, Foster GD, Letizia KA, Stunkard AJ. A multicenter evaluation of a proprietary weight reduction program for the treatment of marked obesity. Arch Intern Med 1991; 152: 961-966.
16. Lönnqvist F, Krief S, Strosberg AD, Nyerg B, Emorine LJ, Arner P. Evidence for a functional β3-adrenoceptor in man. Br J Pharmacol 1993; 110: 929-936.
17. Lafontan M, Berlan M. Fat cell α2-adrenoceptors: The regulation of fat cell function and lipolysis. Endocrine Rev 1995; 16: 716-738.
18. Berlan M, Galitsky J, Reviere D, Foureau M, Tran M, Floers R, Louvet J-P, Houin G, Lafontan M. Plasma catecholamine levels and lipid mobilization induced by yohimbine in obese and non-obese women. Int J Obes 1991; 15: 315-315.