Aza-Wittig reaction of N-vinylic phosphazenes with carbonyl compounds. Azadiene-mediated synthesis of isoquinolines and 5,6-dihydro-2H-1,3-oxazines

Journal of Organic Chemistry

Volumn 62, Issue 4, 1997, Pages 1146-1154

  Palacios, Francisco ^a   Alonso, Concepción ^a   Rubiales, Gloria ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 OXAZINE DERIVATIVE; ISOQUINOLINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030972057     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo961664n     Document Type: Article

References (49)

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46. 1H NMR showing the disappearance of phosphazene 4 and the formation of azadiene 10.
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49. Cycloaddition of azadienes 4 with diethyl ketomalonate was attempted at 120 °C using toluene as solvent, but no reaction took place and starting materials were recovered.