High level of transgene expression in cell cultures and in the mouse by replication-incompetent adenoviruses harboring modified VAI genes

Journal of Virology

Volumn 71, Issue 7, 1997, Pages 5375-5381

  Eloit, M ^a   Adam, M ^a   Gallais, I ^a   Fournier, A ^a  

^a ECOLE NATIONALE VÉTÉRINAIRE D ALFORT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; VIRUS VECTOR;

ADENOVIRUS; ARTICLE; CELL CULTURE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; RNA SEQUENCE; TRANSGENE; VIRUS GENOME; VIRUS REPLICATION;

EID: 0030971781     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.7.5375-5381.1997     Document Type: Article

References (24)

1. Acsadi, G., A. Jani, B. Massie, M. Simoneau, P. Holland, K. Blaschuk, and G. Karpati. 1994. A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity. Hum. Mol. Genet. 3:579-584.
2. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid-guanidinium-thiocyanate-phenol-chloroform extraction. Anal. Biochem. 612:156-159.
3. Eloit, M., and M. Adam. 1995. Isogenic adenoviruses type 5 expressing or not expressing the E1A gene: efficiency as virus vectors in the vaccination of permissive and nonpermissive species. J. Gen. Virol. 76:1583-1589.
4. Eloit, M., P. Gilardi-Hebestreit, B. Toma, and M. Perricaudet. 1990. Construction of a defective adenovirus vector expressing the pseudorabies virus glycoprotein gp50 and its use as a live vaccine. J. Gen. Virol. 71:2425-2431.
5. Ghadge, G. D., P. Malhotra, R. Furtado, R. Dhar, and B. Thimmapaya. 1994. In vitro analysis of virus-associated RNA I (VA-RNA): inhibition of double-stranded RNA-activated protein kinase PKR by VAI-RNA mutants correlates with in vivo phenotype and the structural integrity of the central domain. J. Virol. 68:4137-4151.
6. Gonin, P., W. Oualikene, A. Fournier, and M. Eloit. 1996. Comparison of the efficacy of replication-defective adenovirus and Nyvac poxvirus as vaccine vectors in mice. Vaccine 14:1083-1087.
7. Graham, F. L., J. Smiley, W. C. Russell, and R. Nairn. 1977. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 36:59-72.
8. Graham, F. L., and A. J. Van Der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467.
9. Herrmann, C. H., C. V. Dery, and M. B. Mathews. 1987. Transactivation of host and viral genes by the adenovirus E1B 19K tumor antigen. Oncogene 2:25-35.
10. Herrmann, C. H., and M. B. Mathews. 1989. The adenovirus E1B 19-kilodalton protein stimulates gene expression by increasing DNA levels. Mol. Cell. Biol. 9:5412-5423.
11. Kaufman, R. J. 1985. Identification of the components necessary for adenovirus translational control and their utilization in cDNA expression vector. Proc. Natl. Acad. Sci. USA 82:689-693.
12. Ma, Y., and M. B. Mathews. 1993. Comparative analysis of the structure and function of adenovirus virus-associated RNAs. J. Virol. 67:6605-6617.
13. Mathews, M. B. 1990. Control of translation in adenovirus-infected cells. Enzyme 44:250-264.
14. Mathews, M. B., and T. Shenk. 1991. Adenovirus virus-associated RNA and translation control. J. Virol. 65:5657-5662.
15. Mellits, K. H., and M. B. Mathews. 1988. Effects of mutations in stem and loop regions on the structure and function of adenovirus VA RNA1. EMBO J. 7:2849-2859.
16. Mellits, K. H., M. Kostura, and M. B. Mathews. 1990. Interaction of adenovirus VA RNA1 with the protein kinase DAI: nonequivalence of binding and function. Cell 61:843-852.
17. Mellits, K. H., T. Pe'ery, and M. B. Mathews. 1992. Role of the apical stem in maintaining the structure and function of adenovirus virus-associated RNA. J. Virol. 66:2369-2377.
18. Oualikene, O., P. Gonin, and M. Eloit. 1995. Lack of evidence of phenotypic complementation of E1A/E1B-deleted adenovirus upon superinfection by wild-type virus in cotton rats. J. Virol. 69:6518-6524.
19. Pe'ery, T., K. H. Mellits, and M. B. Mathews. 1993. Mutational analysis of the central domain of adenovirus virus-associated RNA mandates a revision of the proposed secondary structure. J. Virol. 67:3534-3543.
20. Sollerbrant, K., G. Akusjärvi, and C. Svensson. 1993. Repression of RNA polymerase III transcription by adenovirus E1A. J. Virol. 67:4195-4204.
21. Strijker, R., D. T. Fritz, and A. D. Levinson. 1989. Adenovirus VAI-RNA regulates gene expression by controlling stability of ribosome-bound RNAs. EMBO J. 8:2669-2675.
22. Svensson, C., and G. Akusjärvi. 1985. Adenovirus VA RNAI mediates a translational stimulation which is not restricted to the viral mRNAs. EMBO J. 4:957-964.
23. Svensson, C., and G. Akusjärvi. 1990. A novel effect of adenovirus VA RNA1 on cytoplasmic mRNA abundance. Virology 174:613-617.
24. Ventura, M., P. Wang, T. Ragot, M. Perricaudet, and S. Saragosti. 1993. Activation of HIV-specific ribozyme activity by self-cleavage. Nucleic Acids Res. 21:3249-3255.