Acetylcholine-induced relaxation of rat aorta is greatest during estrus in the sexual cycle

Japanese Journal of Pharmacology

Volumn 74, Issue 1, 1997, Pages 113-115

  Honda, Hideo ^a   Ishihara, Hisayuki ^a   Takei, Mai ^a   Kogo, Hiroshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Aorta; Nitric oxide; Sexual cycle

Indexed keywords

ACETYLCHOLINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN;

ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DIESTRUS; ESTRUS; FEMALE; METESTRUS; NONHUMAN; PROESTRUS; RAT; VASODILATATION;

EID: 0030971340     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.74.113     Document Type: Article

References (11)

1. Gant NF, Daley GL, Chand S, Whalley PJ and MacDonald PC: A study of angiotensin-II pressor response throughout primigravida pregnancy. J Clin Invest 52, 2682-2689 (1973)
2. Paller MS: Decreased pressor responsiveness in pregnancy: Studies in experimental animals. Am J Kidney Dis 9, 308-311 (1987)
3. Magness RR and Rosenfeld CR: Mechanism of altered pressor responses to alpha agonists in ovine pregnancy. Am J Obstet Gynecol 159, 252-261 (1988)
4. Weiner CP, Thompson LP, Liu KZ and Herrig JE: Pregnancy reduces serotonin-induced contraction of guinea pig uterine and carotid arteries. Am J Physiol 263, H1764-H1769 (1992)
5. Fuch KL, Grindlay-Moore L and Rounds S: Pulumonary vascular reactivity is blunted in pregnant rats. Eur J Pharmacol 25, 267-269 (1982)
6. Massicotte GS, Louis J, Parant A and Schiffrin EL: Decreased in vitro responses to vasoconstrictors during pregnancy in normotensive and spontaneously hypertensive rats. Can J Physiol Pharmacol 65, 2466-2471 (1987)
7. Aloamaka CP, Ezimokhai M and Morrison J: The role of endothelium in phenylephrine-and potassium-induced contractions of the rat aorta during pregnancy. Res Exp Med 193, 407-417 (1993)
8. Honda H, Kaneko H, Kondo M and Kogo H: Comparison of endothelium-derived relaxing factor activity between nonpregnant and pregnant rats. Comp Biochem Physiol 114C, 193-196 (1996)
9. Weiner CP, Martinez E, Chestnut DH and Ghodsi A: In vitro release of endothelium-derived relaxing factor by acetylcholine is increased during the guinea pig pregnancy. Am J Obstet Gynecol 161, 1605-1610 (1989)
10. Weiner CP, Lizasoain I, Baylis SA, Knowles RG, Charles IG and Moncada S: Induction of calcium-dependent nitric oxide synthases by sex hormones Proc Natl Acad Sci USA 91, 5212-5216 (1994)
11. Watanabe G, Taya K and Sasamoto S: Dynamics of ovarian inhibin secretion during the oestrous cycle of the rat. J Endocrinol 126, 151-157 (1990)