Hypoxia and cobalt stimulate vascular endothelial growth factor receptor gene expression in rats

Pflugers Archiv European Journal of Physiology

Volumn 433, Issue 6, 1997, Pages 803-808

  Sandner, Peter ^a   Wolf, Konrad ^a   Bergmaier, Ulrike ^a   Gess, Bernhard ^a   Kurtz, Armin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Erythropoietin; flk 1; flt 1; flt 4; Tyrosine kinase; Vascular endothelial growth factor

Indexed keywords

CARBON MONOXIDE; COBALT; ERYTHROPOIETIN; MESSENGER RNA; PROTEIN TYROSINE KINASE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HYPOXIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR GENE; REGULATORY MECHANISM;

ANIMALS; ANOXIA; AUTORADIOGRAPHY; CARBON MONOXIDE; COBALT; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; LIVER; LUNG; MALE; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, MITOGEN; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RIBONUCLEASES; RNA, MESSENGER; UP-REGULATION;

EID: 0030971199     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050348     Document Type: Article

References (35)

1. Shweiki D, Itin A, Soffer D, Koshet E (1992) Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845
2. Shweiki D, Neemun M, Itin A, Keshet E (1995) Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor autogenesis. Proc Natl Acad Sci USA 92:768-772
3. Minchenko A, Bauer T, Salceda S, Cam J (1994) Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab Invest 71:374-379
4. Brogi E, Wu T, Namiki A, Isner JM (1994) Indirect angiogenic cytokines upregulute VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only. Circulation 90:649-652
5. Plate KH, Breier G, Weich HA, Risau W (1992) Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359:845-848
6. Goldberg MA, Schneider TJ (1994) Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J Biol Chem 269:4355-4359
7. Levy AP, Levy NS, Loscalzo J, Calderone A, Takahashi N, Kiang-Teck Y, Koren G, Colucci WS, Goldberg MA (1995) Regulation of vascular endothelial growth factor in cardiac myocytes. Circ Res 76:758-766
8. Ikeda E, Achen MG, Breier G, Risau W (1995) Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth (actor in C6 glioma cells. J Biol Chem 270:19761-19766
9. Shima DT, Deutsch U, D'Amore PA (1995) Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability. FEBS Lett 370:203-208
10. Webster KA (1987) Regulation of glycolytic enzyme RNA transcriptional rates by oxygen availability in skeletal muscle cells. Mol Cell Biochem 77:19-28
11. Graven KK, Troxler RF, Kornfeld H, Panchenko MV, Farber HW (1994) Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia. J Biol Chem 269:2446-24453
12. Sandner P, Gess B, Wolf K, Kurtz A (1996) Divergent regulation of vascular endothelial growth factor and of erythropoietin gene expression in vivo. Pflügers Arch 431:905-912
13. Tuder RM, Flook BE, Voelkl NF (1995) Increased gene expression for VEGF and the VEGF Receptors KDR/Flk and Flt in lungs exposed to acute onto chronic hypoxia. J Clin Invest 95:1798-1807
14. Terman BI, Vermazen MD, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D, Bohlen P (1992) Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. Biochem Biophys Res Commun 187: 1579-1586
15. DeVries C, Escobedo JA, Ueno H, Houck KA, Ferrara N, Williams LT (1992) The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:989-991
16. Quinn T, Peters KG, DeVries C, Ferrara N, Williams LT (1993) Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA 90:7533-7537
17. Waltenberger J, Claesson-Welsh L, Siegbahn A, Shibuya M, Heldin CH (1994) Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem 269:26988-26995
18. Ullrich A, Schlessinger J (1990) Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212
19. Pajusola K, Aprelikova O, Korhonen J, Kaipainen A, Pertovaara L, Alitalo R, Alitalo K (1992) flt-4 receptor tyrosine kinase contains seven immunglobulin-like loops and is expressed in multiple human tissues and cell lines. Cancer Res 52:5738-5743
20. Rosnet O, Marchetto S, De Lapeyriere O, Birnbaum D (1991) Murine Flt-3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF-1R familiy. Oncogene 6:1641-1650
21. Kaipainen A, Jorhonen J, Pajusola K, Aprelikova O, Persic MG, Terman BI, Alitalo K (1993) The related flt4, flt1 and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelia cells. J Exp Med 178:2077-2088
22. Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI (1996) Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt-4. Proc Natl Acad Sci USA 93:1988-1992
23. Brogi E, Schatteman G, Wu T, Kim EA, Varticovski L, Keyt B, Isner JM (1996) Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression. J Clin Invest 97:469-476
24. Jelkmann W (1992) Erythropoietin: structure, control of production, and function. Physiol Rev 72:449-489
25. Ratcliffe PJ, Jones RW, Phillips RE, Nicholls LG, Bell JL (1990) Oxygen-dependent modulation of erythropoietin mRNA levels in isolated rat kidneys studied by RNase protection. J Exp Med 172:657-660
26. Tan CC, Eckardt KU, Firth JD, Ratcliffe PJ (1992) Feedback modulation of renal and hepatic erythropoietin mRNA in response to graded anemia and hypoxia. Am J Physiol 263: F474-F481
27. Beru N, McDonald J, Lacombe C, Goldwasser E (1986) Expression of the erythropoietin gen. Mol Cell Biol 6:2571-2575
28. Goldberg MA, Dunning SP, Bunn HF (1988) Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. Science 242:1412-1415
29. Schuster SJ, Badiavas EV, Costa-Giomi P, Weinmann R, Erstev AJ, Caro J (1989) Stimulation of EPO gene transcription during hypoxia and cobalt exposure. Blood 73:13-16
30. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
31. Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M (1990) Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 5:519-524
32. Finnerty H, Kelleher K, Morris GE, Bean K, Merberg DM, Kriz R, Morris JC, Sookdeo H, Turner KJ, Wood CR (1993) Molecular cloning of murine FLT and FLT4. Oncogene 8:2293-2298
33. Letwin K, Yee SP, Pawson T (1988) Novel protein-tyrosine kinase cDNAs related to fps/fes and eph cloned using anti phosphotyrosine antibody. Oncogene 3:621-627
34. Tso JY, Sun XH, Kao TH, Reece KS, Wu R (1985) Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res 13:2485-2502
35. Wang GL, Semenza GL (1993) General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA 90:4304-4308