A helix 1-extended hairpin ribozyme exhibits altered cleavage behavior in vitro

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 2, 1997, Pages 79-87

  Moosbauer, Jutta ^a   Tabler, Martin ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; RIBOZYME; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; RNA SEQUENCE; STRUCTURE ACTIVITY RELATION;

EID: 0030970299     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.79     Document Type: Article

References (3)

1. ALTMAN, S. (1993). RNA enzyme-directed gene therapy. Proc. Natl. Acad. Sci. USA 90, 10898-10900.
2. ANDERSON, P., MONFORTE, J., TRITZ, R., NESBITT, S., HEARST, J., and HAMPEL, A. (1994). Mutagenesis of the hairpin ribozyme. Nucleic Acids Res. 22, 1096-1100.
3. ZOUMADAKIS, M., and TABLER, M. (1995). Comparative analysis of cleavage rates after systematic permutation of the NUX ↓ consensus target motif for hammerhead ribozymes. Nucleic Acids Res. 23, 1192-1196.