Synthesis and structure-activity relationships of 17β-substituted 14β- hydroxysteroid 3-(α-l-rhamnopyranoside)s: Steroids that bind to the digitalis receptor

Journal of Medicinal Chemistry

Volumn 40, Issue 10, 1997, Pages 1439-1446

  Templeton, John F ^a   Ling, Yangzhi ^a   Marat, Kirk ^a   LaBella, Frank S ^b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

14BETA HYDROXY 21 NITRO 3BETA (ALPHA L RHAMNOPYRANOSYLOXY) 5BETA PREGN 20 ENE; 14BETA HYDROXY 3BETA (ALPHA L RHAMNOPYRANOSYLOXY) 5BETA PREGNANE 21 CARBOXYLIC ACID 14,21 LACTONE; 14BETA HYDROXYSTEROID 3 (ALPHA L RHAMNOPYRANOSIDE); 3BETA (ALPHA L RHAMNOPYRANOSYLOXY) 17BETA METHYLENE 5BETA ANDROSTANE 14BETA,20 EPOXIDE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALUMINUM; DIGITALIS; DRUG RECEPTOR; ETHER; ISOENZYME; LACTONE; LITHIUM; OUABAIN; PYRANOSIDE; RADIOLIGAND; STEROID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARDIOTOXICITY; DOG; DRUG POTENCY; DRUG SYNTHESIS; LIGAND BINDING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RECEPTOR BINDING; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; DOGS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSOMES; MYOCARDIUM; NA(+)-K(+)-EXCHANGING ATPASE; OUABAIN; PROTEIN BINDING; RADIOLIGAND ASSAY; RHAMNOSE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030969923     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960880l     Document Type: Article

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