Effect of inhibition of pentagastrin-stimulated acid secretion on gastric mucosal gland luminal pressure

Acta Physiologica Scandinavica

Volumn 160, Issue 1, 1997, Pages 103-111

  Synnerstad, I ^a,b   Persson, A E G ^a   Holm, L ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Box 572 ^*  (Sweden)

Author keywords

Gastric acid; Gastric gland; Micropuncture; Omeprazole; Pentagastrin; Ranitidine; Rat

Indexed keywords

OMEPRAZOLE; PENTAGASTRIN; RANITIDINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HYDROSTATIC PRESSURE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH ACID; STOMACH ACID SECRETION; STOMACH GLAND; STOMACH MUCOSA;

EID: 0030969170     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1997.00125.x     Document Type: Article

References (24)

1. Bhaskar, K.R., Garik, P., Turner, B.S., Bradley, J.D., Bansil, R., Stanley, H.E. & LaMont J.T. 1992. Viscous fingering of HCL through gastric mucin. Nature 360, 458-461.
2. Boulay, K., Blanlœil Y., Bourveau, M. Geay, G. & Malinovsky, J.M. 1994. Effects of oral ranitidine, famotidine and omeprazole on gastric volume and pH at induction and recovery from general anaesthesia. Br J Anaesth 73, 475-478.
3. Ewart, M.C., Yau, G., Gin, T., Kotur, C.F. & Oh, T.E. 1990. A comparison of the effects of omeprazole and ranitidine on gastric secretion in women undergoing elective Caesarean section. Anaesthesia 45, 527-530.
4. Fein, H. 1972. Microdimensional pressure measurements in electrolytes. J Appl Physiol 32 (4), 560-564.
5. +-ATPase blockade. Am J Physiol 254 (Gastrointest Liver Physiol 17), G399-G407.
6. Grider, J.R. & Makhlouf, G.M. 1990. Distinct receptors for cholecystokinin and gastrin on muscle cells of stomach and gallbladder. Am J Physiol 259 (Gastrointest Liver Physiol 22), G184-G190.
7. Hattori, T. 1974. On cell proliferation and differentiation of the fundic mucosa of the golden hamster. Cell Tiss Res 148, 213-226.
8. Helander, H.F., Mansson, H., Elm, G. & Ottosson, S. 1 (990) Structure and function of rat parietal cells during treatment with omeprazole, SCH 28080, SCH 32651, or ranitidine. Scand J Gastroenterol 25, 799-809.
9. Helander, H.F. & Sundell, G.W. 1984. Ultrastructure of inhibited parietal cells in the rat. Gastroenterology 87, 1064-1071.
10. Holm, L. & Flemström, G. 1990. Microscopy of acid transport at the gastric surface in vivo. J Int Med 228 (suppl 1), 91-95.
11. Holm-Rutili, L. 1987. Effects of omeprazole on gastric mucosal microcirculation and acid secretion in the rat. Gastroenterology 92, 716-723.
12. Holm, L., Ågren, J. & Persson, A.E.G. 1992. Stimulation of acid secretion increases the gastric gland luminal pressure in the rat. Gastroenterology 103, 1797-1803.
13. Holm-Rutili, L. & Öbrink, K.J. 1985. Rat gastric mucosal microcirculation in vivo. Am J Physiol 248 (Gastrointest Liver Physiol 11), G741-G746.
14. Larsson, H., Carlsson, E., Junggren, U., Olbe, L., Sjöstrand, SE., Skånberg, I. & Sundell, G. 1983. Inhibition of gastric acid secretion by omeprazole in the dog and rat. Gastroenterology 85, 900-907.
15. Lind, T., Cederberg, C., Ekenved, G., Haglund, U. & Olbe, L. 1983. Effect of omeprazole- a gastric proton pump inhibitor- on pentagastrin stimulated acid secretion in man. Gut 24, 270-276.
16. Menozzi, D., Gardner, J.D., Jensen, R.T. & Maton, P.N. 1989. Properties of receptors for gastrin and CCK on gastric smooth muscle cells. Am J Physiol 257 (Gastrointest Liver Physiol 20), G73-G79.
17. Morgan, K.G., Angel, F., Schmalz, P.F. & Szurszewski, J.H. 1985. Intracellular electrical activity of muscularis mucosae of the dog stomach. Am J Physiol 249 (Gastrointest Liver Physiol 12), G256-G263.
18. Ruckebusch, M. & Fioramonti, J. 1975. Electrical spiking activity and propulsion in small intestine in fed and fasted rats. Gastroenterology 68, 1500-1508.
19. Schade, C., Flemström, G. & Holm, L. 1994. Hydrogen ion concentration in the mucus layer on top of acid stimulated and inhibited rat gastric mucosa. Gastroenterology 107, 180-188.
20. Seelig, L.L., Schlusselberg, D.S., Smith, W.K. & Woodward, D.J. 1985. Mucosal nerves and smooth muscle relationships with gastric glands of the opossum: an ultrastructural and three-dimensional reconstruction study. Am J Anat 174, 15-26.
21. Stolte, M., Bethke, B., Rühl, G. & Ritter, M. 1992. Omeprazole-induced pseudohypertrophy of gastric parietal cells. Z Gastroenterol 30,134-138.
22. Synnerstad, I. & Holm, L. 1995. Omeprazole increases the gastric mucosal gland luminal pressure. Gastroenterology 108 (4), A230.
23. Wallmark, B., Jaresten, BM., Larsson, H., Ryberg, B., Brändström, A. & Fellenius, E. 1983. Differentiation among inhibitory actions of omeprazole, cimetidine, and SCN- on gastric acid secretion. Am J Physiol 245 (Gastrointest Liver Physiol 8), G64-G71.
24. Wiederhielm, C.A., Woodbury, J.W., Kirk, S. & Rushmer, R.F. 1964. Pulsatile pressures in the microcirculation of frog's mesentery. Am J Physiol 207 (1), 173-176.