Drug-induced transmembrane lipid scrambling in erythrocytes and in liposomes requires the presence of polyanionic phospholipids

Molecular Membrane Biology

Volumn 14, Issue 1, 1997, Pages 5-12

  Moreau, Carole ^a   Sulpicet, Jean Claude ^b   Devaux, Philippe F ^a   Zachowski, Alain ^a,b  

^a INST DE BIOLOGIE PHYSICO CHIMIQUE   (France)

^b CNRS   (France)

Author keywords

Lipid asymmetry; Liposome; Membrane; PIP2; Scrambling

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINOPHOSPHOLIPID; CARDIOLIPIN; CHLORPROMAZINE; CHLORPROMAZINE DERIVATIVE; IMIPRAMINE; LIPID; LIPOSOME; MEMBRANE LIPID; MEMBRANE PHOSPHOLIPID; PHENIRAMINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLSERINE; POLYANION; PRIMAQUINE; SPHINGOMYELIN; VERAPAMIL; VINBLASTINE;

ARTICLE; ARTIFICIAL MEMBRANE; CONTROLLED STUDY; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; LIPID VESICLE; MEMBRANE STRUCTURE; PRIORITY JOURNAL;

EID: 0030968915     PISSN: 09687688     EISSN: None     Source Type: Journal    
DOI: 10.3109/09687689709048163     Document Type: Article

References (33)

1. Bassé, F., Gaffet, P., Rendu, F. and Bienvenue, A. (1993) Translocation of spin-labeled phospholipids through plasma membrane during thrombin-and ionophore A23187-induced platelet activation. Biochemistry, 32, 2337-2344.
2. 2+-dependent transbilayer movement of phospholipids. Journal of Biological Chemistry, 274, 17205-17210.
3. Bevers, E. M., Tilly, R. H. J., Senden, J. M. G., Comfurius, P. and Zwaal, R. F. A. (1989) Exposure of endogenous phosphatidylserine at the outer surface of stimulated platelets is reversed by restoration of aminophospholipid translocase activity. Biochemistry, 28, 2382-2387.
4. 2+-induced loss of phospholipid asymmetry in the human erythrocyte: a study in Scott syndrome, a disorder of calcium-induced phospholipid scrambling. Blood, 86, 1983-1991.
5. Butikofer, P., Lin, Z. W., Kuypers, F. A., Scott, M. D., Xu, C. M., Wagner, G. M., Chiu, D. T. and Lubin, B. (1989) Chlorpromazine inhibits vesiculation, alters phosphoinositide turnover and changes deformability of ATP-depleted RBCs. Blood, 73, 1699-1704.
6. Colin, F. C. and Schrier, S. L. (1991) Spontaneous endocytosis in human neonatal and adult red blood cells: comparison to drug-induced endocytosis and to receptor-mediated endocytosis. American Journal of Hematology, 37, 34-40.
7. Comfurius, P., Williamson, P., Smeets, E. F., Schlegel, R. A. and Zwaal, R. F. A. (1996) Reconstitution of phospholipid scramblase activity from human blood platelets. Biochemistry 35, 7631-7634.
8. Daleke, D. L. and Huestis, W. H. (1985) Incorporation and translocation of aminophospholipids in human erythrocytes. Biochemistry, 24, 5406-5416.
9. de Wolf, F. A., Demel, R. A., Bets, D., van Kats, C. and de Kruijff, B. (1991) Characterization of the interaction of doxorubicin with (poly)phosphoinositides in model systems. Evidence for specific interaction with phosphatidylinositol-monophosphate and diphosphate. FEBS Letters, 288, 237-240.
10. Deuticke, B. (1968) Transformation and restoration of biconcave shape of human erythrocytes induced by amphiphilic agents and changes of ionic environment. Biochimica et Biophysica Acta, 163, 494-500.
11. Devaux P. F. (1992) Protein involvement in transmembrane lipid asymmetry. Annual Review of Biophysics and Biomolecular Structure, 21, 417-439.
12. Fellmann, P., Zachowski, A. and Devaux, P. F. (1994) Synthesis and use of spin-labeled lipids for studies of the transmembrane movement of phospholipids. In Methods in molecular biology, J. M. Graham and J. A. Higgins, eds (Humana Press Inc., Totowa NJ), vol. 27-II, pp. 161-175.
13. Ferrell, J. E. and Huestis, W. H. (1984) Phosphoinositide metabolism and the morphology of human erythrocytes. Journal of Cell Biology, 98, 1992-1998.
14. Ferrell, J. E., Lee, K.-J. and Huestis, W. H. (1985) Membrane bilayer balance and erythrocyte shape: a quantitative assessment Biochemistry, 24, 2849-2857.
15. Gascard, P., Journet, E., Sulpice, J. C. and Giraud, F. (1989) Functional heterogeneity of polyphosphoinositides in human erythrocytes. Biochemical Journal, 264, 547-553.
16. Gascard, P., Tran, D., Sauvage, M., Sulpice, J.-C., Fukami, T., Claret, M. and Giraud, F. (1991) Asymmetric distribution of phosphoinositides and phosphatidic acid in the human erythrocyte membrane. Biochimica et Biophysica Acta, 1069, 27-36.
17. Goormaghtigh, E., Chatelain, P., Caspers, J. and Ruysschaert, J. M. (1980) Evidence of a specific complex between adriamycin and negatively-charged phospholipids. Biochimica et Biophysica Acta, 597, 1-14.
18. Hope, M. J., Bally, M. B., Webb, G. and Cullis, P. R. (1985) Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential. Biochimica et Biophysica Acta, 812, 55-65.
19. 14C-labeled quaternary ammonium compounds of promazine, chlorpromazine and trifluoropromazine. Journal of Pharmaceutical Science, 59, 1114-1118.
20. 2+-crenated and recovered human erythrocytes. Biochemistry, 33, 7337-7344.
21. Nicolay, K., Timmers, R. J. M., Spoelstra, E., van der Neut, R., Fok, J. J., Huigen, Y. M., Verkleij, A. J. and de Kruijff, B. (1984) The interaction of adriamycin with cardiolipin in model and rat liver mitochondrial membranes. Biochimica et Biophysica Acta, 778, 359-371.
22. Rosso, J., Zachowski, A. and Devaux, P. F. (1988) Influence of chlorpromazine on the transverse mobility of phospholipids in the human erythrocyte membrane: relation to shape changes. Biochimica et Biophysica Acta, 942, 271-279.
23. Schrier, S. L., Chiu, D. T.-Y., Yee, M., Sizer, K. and Lubin, B. (1983) Alteration of membrane phospholipid bilayer organization in human erythrocytes during drug-induced endocytosis. Journal of Clinical Investigations, 72, 1698-1705.
24. Schrier, S. L., Zachowski, A. and Devaux, P. F. (1992) Mechanisms of amphipath induced stomatocytosis in human erythrocytes Blood, 79, 782-786.
25. Schroit, A. J. and Zwaal, R. F. A. (1991) Transbilayer movement of phospholipids in red cell and platelet membranes. Biochimica et Biophysica Acta, 1071, 313-329.
26. Seigneuret, M. and Devaux, P. F. (1984) ATP-dependent asymmetric distribution of spin-labeled phospholipids in the erythrocyte membrane: relation to shape change. Proceedings of the National Academy of Sciences of the USA, 81, 3751-3755.
27. Seigneuret, M., Zachowski, A., Herrmann, A. and Devaux, P. F. (1984) Asymmetric lipid fluidity in human erythrocyte membrane: new spin-label evidence. Biochemistry, 23, 4271-4275.
28. Sheetz, M. P. and Singer, S. J. (1974) Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interaction. Proceedings of the National Academy of Sciences of the USA, 71, 4457-4461.
29. 2+ induced phospholipid redistribution in the human erythrocyte membrane. Journal of Biological Chemistry, 269, 6347-6354.
30. 2+ and spermine on phosphatidylinositol 4,5-bisphosphate-mediated transmembtane redistribution of phospholipids in large unilamellar vesicles and in erythrocytes. Biochemistry, 35, 13345-13352.
31. 2+ induces transbilayer redistribution of all major phospholipids in human erythrocytes. Biochemistry, 31, 6355-6360.
32. Zachowski, A. (1993) Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement. Biochemical Journal, 294, 1-14.
33. Zachowski, A., Favre, E., Cribier, S., Hervé, P. and Devaux, P. F. (1986) Outside-inside translocation of aminophospholipids in the human erythrocyte membrane is mediated by a specific enzyme. Biochemistry, 25, 2585-2590.