Systemic effect of intrathecal methotrexate during the initial phase of treatment of childhood acute lymphoblastic leukemia

Journal of Clinical Oncology

Volumn 15, Issue 5, 1997, Pages 1824-1830

  Thyss, Antoine ^a   Suciu, Stefan ^b   Bertrand, Yves ^b   Mazingue, Françoise ^b   Robert, Alain ^b   Vilmer, Etienne ^b   Mechinaud, Françoise ^b   Benoit, Yves ^b   Brock, Pénélope ^b   Ferster, Alina ^b   Lutz, Patrick ^b   Boutard, Patrick ^b   Marguerite, Geneviève ^b   Plouvier, Emmanuel ^b   Michel, Gérard ^b   Plantaz, Dominique ^b   Munzer, Martine ^b   Rialland, Xavier ^b   Chantraine, Jean Marie ^b   Norton, Lucilia ^b   Solbu, Gabriel ^b   Philippe, Noël ^b   Otten, Jacques ^b   more..

^a CENTRE ANTOINE LACASSAGNE   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; METHOTREXATE; PREDNISOLONE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B LYMPHOCYTE; CANCER SURVIVAL; CHILD; CHILDHOOD CANCER; DOSE RESPONSE; FEMALE; HUMAN; INTRATHECAL DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; T LYMPHOCYTE;

EID: 0030968890     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1997.15.5.1824     Document Type: Article

References (13)

1. Riehm H, Reiter A, Schrappe M, et al: Die Corticosteroidabhängige Dezimierung der Leukämiezellzahl im Blut als Prognosefaktor bei der akuten lymphoblastischen Leukämie im Kindesalter. Klin Paediatr 199:151-160, 1986
2. Kendall MG: Rank Correlations Methods. Griffen and Co, London, United Kingdom, 1962
3. Cox DR: The Analysis of Binary Data. Mathuen, London, United Kingdom, 1970
4. Pession A, Rondelli R, Vecchi V, et al: Preinduction therapy response in childhood ALL protocols ('87-'88) of the Italian Association for Pediatric Hematology and Oncology. Med Pediatr Oncol 21:555, 1993 (abstr)
5. Bleyer W, Dedrick R: Clinical pharmacology of intrathecal methotrexate. Pharmacokinetics in non-toxic patients after lumbar injection. Cancer Treat Rep 61:703-708, 1977
6. Ettinger LJ, Chervinsky DS, Freeman AI, et al: Pharmacokinetics of methotrexate following intravenous and intraventricular administration in acute lymphocytic leukemia and non-Hodgkin's lymphoma. Cancer 50:1676-1682, 1982
7. Chabner BA, Young R: Threshold methotrexate concentration for in vivo inhibition DNA synthesis in normal and tumorous target tissues. J Clin Invest 52:1804-1811, 1973
8. Tubiana N, Monjanel S, Maraninchi D, et al: in Holdebrand J, Gangji D (eds): Treatment of Neoplastic Lesions of the Nervous System. Oxford, United Kingdom, and New York, NY, Pergamon, 1982, pp 15-19
9. Simmons E, Somberg K: Acute tumor lysis syndrome after intrathecal methotrexate administration. Cancer 67:2062-2065, 1991
10. Pieters R, Kaspers G, Klumper E, et al: Clinical relevance of in vitro drug resistance testing in childhood acute lymphoblastic leukemia: The state of the art. Med Pediatr Oncol 22:299-308, 1994
11. Quddus FF, Leventhal BG, Boyett JM, et al: Glucocorticoid receptors in immunological subtypes of childhood acutelymphocytic leukemia cells. A Pediatric Oncology Group study. Cancer Res 45:6842-6846, 1985
12. Goker E, Lin JT, Tripett T, et al: Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease. Leukemia 7:1000-1004, 1993
13. Barredo JC, Synold TW, Laver J, et al: Difference in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia. Blood 84:564-569, 1994