Cloning of Drosophila MCM homologs and analysis of their requirement during embryogenesis

Gene

Volumn 192, Issue 2, 1997, Pages 283-289

  Su, Tin Tin ^a   Yakubovich, Nikita ^a   O'Farrell, Patrick H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell cycle; DNA replication; MCM4; MCM5

Indexed keywords

ANTIBODY; DNA; TRANSCRIPTION FACTOR;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DNA REPLICATION; DROSOPHILA MELANOGASTER; EMBRYO; EMBRYO DEVELOPMENT; GENE FUNCTION; GENE SEQUENCE; GENETIC CONSERVATION; MINICHROMOSOME; MITOSIS; MOLECULAR CLONING; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE PROTEINS; CLONING, MOLECULAR; DNA REPLICATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENES, INSECT; IMMUNOLOGIC TECHNIQUES; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0030968796     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(97)00107-8     Document Type: Article

References (22)

1. Brown, N.H., Kafatos, F.C., 1988. Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203, 425-437.
2. Bull, C.J., White, O., Olsen, G.J., 1996. Complete genome sequence of the Methanogenic Archaeon, Methanococcus jannaschii. Science 273, 1058-1073.
3. Chong, J.P., Mahbubani, H.M., Khoo, C.Y., Blow, J.J., 1995. Purification of an MCM-containing complex as a component of the DNA replication licensing system. Nature 375, 418-421.
4. Chong, J.P.J., Thommes, P., Blow, J.J., 1996. The role of MCM/P1 proteins in the licensing of DNA replication. Trends Biochem. Sci. 21, 102-106.
5. Edgar, B.A., Schubiger, G., 1986. Parameters controlling transcriptional activation during early Drosophila development. Cell 44, 871-877.
6. Feger, G., Vaessin, H., Su, T.T., Wolff, E., Jan, L.Y., Jan, Y.N., 1995. dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila. EMBO J. 14, 5387-5398.
7. Foe, V.E., 1989. Mitotic domains reveal early commitment of cells in Drosophila embryos. Development 107, 1-22.
8. Foe, V.E., Odell, G.M. and Edgar, B.A., 1993. Mitosis and morphogenesis in the Drosophila embryo. In: Bate, M. and Martinez Arias, A. (Eds.), The Development of Drosophila melanogaster. CSHL Press, Cold Spring Harbor, NY.
9. Holthoff, H.P., Hameister, H., Knippers, R., 1996. A novel human Mem protein homology to the yeast replication protein Mis5 and chromosomal location. Genomics 37, 131-134.
10. Kearsey, S.E., Maiorano, D., Holmes, B.C., Todorov, I.T., 1996. The role of MCM proteins in the cell cycle control of genome duplication. Bioessays 3, 183-190.
11. Kimura, H., Nozaki, N., Sugimoto, K., 1994. DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. EMBO J. 13, 4311-4320.
12. Kubota, Y., Mimura, S., Nishimoto, S., Takisawa, H., Nojima, H., 1995. Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor. Cell 81, 601-609.
13. Li, J.J., Herskowitz, I., 1993. Isolation of ORC6, a component of the yeast origin recognition complex by a one-hybrid system. Science 262, 1870-1874.
14. Madine, M.A., Khoo, C.-Y., Mills, A.D., Laskey, R.A., 1995. An MCM3 protein complex is required for cell cycle regulation of DNA replication in vertebrate cells. Nature 375, 421-424.
15. Raff, J.W., Glover, D.M., 1988. Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin. J. Cell. Biol. 107, 2009-2019.
16. Sambrook, J., Fritsch, E.F. and Maniatis, T., 1989. Molecular Cloning. A Laboratory Manual. CSHL Press, Cold Spring Harbor, NY.
17. Schubiger, G. and Edgar, B., 1994. Using inhibitors to study embryo-genesis. In: Methods in Cell Biology. Academic Press, New York, pp. 697-713.
18. Spradling, A., Orr-Weaver, T., 1987. Regulation of DNA replication during Drosophila development. Annu. Rev. Genet. 21, 373-403.
19. Su, T.T., Feger, G., O'Farrell, P.H., 1996. Drosophila MCM protein complexes. Mol. Biol. Cell. 7, 319-329.
20. Todorov, I.T., Pepperkok, R., Philipova, R.N., Kearsey, S.E., Ansorge, W., Werner, D., 1994. A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division. J. Cell Sci. 107, 253-265.
21. Treisman, J.E., Follette, P.J., O'Farrell, P.H., Rubin, G.M., 1995. Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant. Genes Dev. 9, 1709-1715.
22. Tye, B.-K., 1994. The MCM2-3-5 proteins: are they replication licensing factors? Trends Cell. Biol. 4, 160-166.