Advantage of dimeric peptide antigens in serodiagnosis of HIV-1 infection

Microbiology and Immunology

Volumn 41, Issue 3, 1997, Pages 215-220

  Gokulan, Kuppan ^a,c   Tripathi, Srikant Prasad ^b   Rao, D Nageshwara ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b National AIDS Research Center   (India)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Peptide antigens; Serodiagnosis

Indexed keywords

GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; SYNTHETIC PEPTIDE;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIMERIZATION; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; PEPTIDE SYNTHESIS; SERODIAGNOSIS;

EID: 0030968405     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.1997.tb01193.x     Document Type: Article

References (17)

1. Averameas, S., and Ternynck, T. 1969. The cross linking of proteins with glutaraldehyde and its use for the preparation of immunosorbants. Immunochemistry 6: 43-47.
2. Bell, S.J.D., Cooper, D.A., Kemp, B.E., Doherty, R.R., and Penny, R. 1992. Definition of an immunodominant T cell epitope contained in the envelope gp41 sequence of HIV-1. Clin. Exp. Immunol. 87: 37-45.
3. Brain, F., McLane, M.F., Allan, J.S., Lee, T.H., Groopman, J.E., and Essex, M. 1985. Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients. Science 228: 1094-1096.
4. Boudet, F., Girard, M., Theze, J., and Zouali, M. 1992. Antibodies of HIV-1 positive subjects and experimentally immunized primates and rodents bind to sequence divergent regions of third variable domain of gp120. Int. Immunol. 4: 283-294.
5. Denis, F., Damet, G.G., Lhuillier, M., Leonard, G., Goudeau, A., Essex, M., Brain, F., Rey, J.-L., Mounier, M., Sangare, A., M'Boup, S., and Kanki, P. 1987. Prevalence of human T-lymphotrophic retrovirus type III (HIV) and type IV in Ivory coast. Lancet I: 408-411.
6. Gallo, R.C., Salahuddhin, S.Z., Popovic, M., Shearer, G.M., Kaplan, M., Haynes, B.F., Palker, T.J., Redfield, R., Oleske, J., and Safai, B. 1984. Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS at risk for AIDS. Science 224: 500-503.
7. Gnann, J.W., McCormick, J.B., Mitchell, S., Nelson, J.A., and Oldstone, M.B.A. 1987. Synthetic peptide immunoassay distinguishes HIV type-I and type-II infections. Science 237: 1346-1349.
8. Gnann, J.W., Schwimmbeck, P.L., Nelson, J.A., Traux, A.B., and Oldstone, M.B.A. 1987. Diagnosis of AIDS by using a 12 amino acid peptide representing an immunodominant epitope of HIV. J. Infect. Dis. 156: 261-267.
9. Kanika, P.J., M'Boup, S., Richard, D., Brain, F., Denis, F., Boye, C., Sangare, L., Travers, K., Albaum, M., Marlink, R., Lemonne, J.L.R., and Essex, M. 1987. Human T-lymphotrophic virus type-4 and the human immunodeficiency virus in West Africa. Science 236: 827-831.
10. Marsden, H.S., Owsianka, A.M., Graham, S., McLean, G.W., Robertson, C.A., and Subak-Sharpe, J.H. 1992. Advantages of branched peptides in serodiagnosis. Detection of HIV-specific antibodies and the use of glycine spacers to increase sensitivity. J. Immunol. Methods 147: 65-72.
11. Merrifield, R.B. 1963. Solid phase peptide synthesis. J. Am. Soc. 85: 2149-2154.
12. Narvanen, A., Korkolainen, M., Suni, J., Korpela, J., Kohtia, S., Partanen, P., Vaheri, A., and Huhtala, M.-L. 1988. Synthetic env gp41 peptide as a sensitive and specific diagnostic reagent in different stages of human immunodeficiency virus type-I infection. J. Med. Virol. 26: 111-118.
13. Palker, T.J., Matthews, T.J., Clark, M.E., Cianicolo, G.J., Randall, R.R., Landlois, A.J., White, C.G., Safi, B., Snyderman, R., Bolognosi, D.P., and Haynes, B.F. 1987. Conserved region at COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope. Proc. Natl. Acad. Sci. U.S.A. 84: 2479-2483.
14. Stewart, J.M., and Young, J.D. 1984. Solid phase peptide synthesis. Second edition, Pirvic chemical co-Rockford-IL-83.
15. Tam, J.P., and Zavala, F. 1989. Multiple antigen epitope. A novel approach to increase detection sensitivity of synthetic peptides in solid phase immunoassays. J. Immunol. Methods 124: 53-61.
16. Veronese, F.D.M., DeVico, A.L., Copeland, T.P., Oroszlan, S., Gallo, R.C., and Sarngadharan, M.G. 1985. Characterization of gp41 as the transmembrane protein coded by HTLV-III/LAV envelope gene. Science 229: 1402-1405.
17. Veronese, F.D.M., Copeland, T.D., DeVico, A.L., Rahman, R., Oroszlan, S., Gallo, R.C., and Sarngadharan, M.G. 1986. Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV Science 231: 1289-1291.