Molecular analysis of INK4 genes in breast carcinomas

International Journal of Oncology

Volumn 11, Issue 4, 1997, Pages 737-744

  Spirin, Konstantin S ^a   Simpson, Jean F ^b   Miller, Carl W ^a   Phillip Koeffler, H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Amplification; Cyclin dependent kinase inhibitor; D cyclin; Deletion; Missense mutation; P15(INK4B); P16(INK4A); P18(INK4C); P19(INK4D); PCR SSCP

Indexed keywords

ARTICLE; BREAST CARCINOMA; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CLINICAL ARTICLE; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENTIAL ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0030967934     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.11.4.737     Document Type: Article

References (5)

1. Kamb A: Cell-cycle regulators and cancer. TIG 11: 136-140, 1995.
2. Cordon-Cardo C: Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia. Am J Pathol 147: 545-560, 1995.
3. Hunter T and Pines J: Cyclins and cancer. II: cyclin D and CDK inhibitors come of age. Cell 79: 573-582, 1994.
4. Sherr CJ: D-type cyclins. TIBS 20: 187-190, 1995.
5. Wang JYJ, Knudsen ES and Welch PJ: The retinoblastoma tumor suppressor protein. Adv Cancer Res 64: 25-85, 1994.