메뉴 건너뛰기




Volumn 13, Issue 4, 1997, Pages 509-518

Stress and neuroendocrine plasticity;Stress et plasticite neuroendocrinienne

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; EMOTIONALITY; LACTATION; NERVE CELL PLASTICITY; NEUROENDOCRINE SYSTEM; PERINATAL DEVELOPMENT; REVIEW; STRESS; SYNAPTOGENESIS;

EID: 0030966792     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.4267/10608/406     Document Type: Review
Times cited : (6)

References (55)
  • 3
    • 0030043899 scopus 로고    scopus 로고
    • Immune-neuro-endocrine interactions: Facts and hypothesis
    • Besedovsky HO, Del Rev A. Immune-neuro-endocrine interactions: facts and hypothesis. Endocrinol Rev 1996; 17: 64-102.
    • (1996) Endocrinol Rev , vol.17 , pp. 64-102
    • Besedovsky, H.O.1    Del Rev, A.2
  • 4
    • 0021691828 scopus 로고
    • Corticosteroid inhibition of ACTH secretion
    • Keller-Wood ME, Dallman MF. Corticosteroid inhibition of ACTH secretion. Endocrinol Rev 1984; 5: 1-24.
    • (1984) Endocrinol Rev , vol.5 , pp. 1-24
    • Keller-Wood, M.E.1    Dallman, M.F.2
  • 5
    • 0027531626 scopus 로고
    • Stress update: Adaptation of the hypothalamic-pituitary-adrenal axis to chronic stress
    • Dallman MF. Stress update: adaptation of the hypothalamic-pituitary-adrenal axis to chronic stress. Trends Endocrinol Metab 1993; 4: 62-9.
    • (1993) Trends Endocrinol Metab , vol.4 , pp. 62-69
    • Dallman, M.F.1
  • 6
    • 0028131425 scopus 로고
    • Stress and psychiatric disorders
    • Stout SC, Nemeroff CB. Stress and psychiatric disorders. Semin Neurol 1994; 6: 271-89
    • (1994) Semin Neurol , vol.6 , pp. 271-289
    • Stout, S.C.1    Nemeroff, C.B.2
  • 7
    • 0026647022 scopus 로고
    • Chronic psychosocial stress enhances vasopressin, but not corticotropin-releasing factor in the external zone of the median eminence of male rats: Relationship to subordinate status
    • DeGoeij DCE, Dijkstra H, Tilders FJH. Chronic psychosocial stress enhances vasopressin, but not corticotropin-releasing factor in the external zone of the median eminence of male rats: relationship to subordinate status. Endocrinology 1992; 131: 847-53.
    • (1992) Endocrinology , vol.131 , pp. 847-853
    • DeGoeij, D.C.E.1    Dijkstra, H.2    Tilders, F.J.H.3
  • 8
    • 0025808275 scopus 로고
    • Chronic streptozotocin-diabetes in rats facilitates the acute stress response without altering pituitary or adrenal responsiveness to secretagogues
    • Scribner KA, Walker CD, Cascio CS, Dallman MF. Chronic streptozotocin-diabetes in rats facilitates the acute stress response without altering pituitary or adrenal responsiveness to secretagogues. Endocrinology 1991; 129: 99-108.
    • (1991) Endocrinology , vol.129 , pp. 99-108
    • Scribner, K.A.1    Walker, C.D.2    Cascio, C.S.3    Dallman, M.F.4
  • 10
  • 11
    • 0014107589 scopus 로고
    • Body weight and food consumption of lactating rats nursing various sizes of litters
    • Ota K, Yokoyama A. Body weight and food consumption of lactating rats nursing various sizes of litters. J Endocrinol 1967; 38: 263-8.
    • (1967) J Endocrinol , vol.38 , pp. 263-268
    • Ota, K.1    Yokoyama, A.2
  • 12
    • 0011724206 scopus 로고
    • Brain mechanisms of maternal behavior in the rat
    • Balthazart J, Prove E, Gilles R, eds. Berlin: Springer-Verlag
    • Numan M. Brain mechanisms of maternal behavior in the rat. In: Balthazart J, Prove E, Gilles R, eds. Hormones and behavior in higher vertebrates. Berlin: Springer-Verlag, 1983: 69-85.
    • (1983) Hormones and Behavior in Higher Vertebrates , pp. 69-85
    • Numan, M.1
  • 13
    • 0028076917 scopus 로고
    • Involvement of corticotropin-releasing hormone and endogenous opioid peptides in prolactin-suppressed gonadotropin-releasing hormone release in vitro
    • Calogero AE, Weber RFA, Raiti F, Burrello N, Moncada ML, Mongioi A, D'Agata R. Involvement of corticotropin-releasing hormone and endogenous opioid peptides in prolactin-suppressed gonadotropin-releasing hormone release in vitro. Neuroendocrinology 1994; 60: 291-6.
    • (1994) Neuroendocrinology , vol.60 , pp. 291-296
    • Calogero, A.E.1    Weber, R.F.A.2    Raiti, F.3    Burrello, N.4    Moncada, M.L.5    Mongioi, A.6    D'Agata, R.7
  • 14
    • 0014495061 scopus 로고
    • Inhibition of lactation and luteal function in postpartum rats by hypothalamic implantation of prolactin
    • Clemens JA, Sar M, Meites J. Inhibition of lactation and luteal function in postpartum rats by hypothalamic implantation of prolactin. Endocrinology 1969; 84: 868-72.
    • (1969) Endocrinology , vol.84 , pp. 868-872
    • Clemens, J.A.1    Sar, M.2    Meites, J.3
  • 15
    • 0025552138 scopus 로고
    • Role of neuropeptide Y in reproductive function
    • McDonald JK. Role of neuropeptide Y in reproductive function. Ann NY Acad Sci 1993; 692: 258-71.
    • (1993) Ann NY Acad Sci , vol.692 , pp. 258-271
    • McDonald, J.K.1
  • 16
    • 0027177429 scopus 로고
    • Involvement of central corticotropin-releasing factor (CRF) in suckling-induced inhibition of luteinizing hormone secretion in lactating rats
    • Walker CD, Dallman MF, Palmer AA, Steele MK. Involvement of central corticotropin-releasing factor (CRF) in suckling-induced inhibition of luteinizing hormone secretion in lactating rats. J Neuroendocrinol 1993; 5: 451-9.
    • (1993) J Neuroendocrinol , vol.5 , pp. 451-459
    • Walker, C.D.1    Dallman, M.F.2    Palmer, A.A.3    Steele, M.K.4
  • 17
    • 0027310240 scopus 로고
    • CRF alters the infundibular LHRH secretory system from the medial preoptic area of female rats: Possible involvement of opioid receptors
    • Rivest S, Plotsky PM, Rivier C. CRF alters the infundibular LHRH secretory system from the medial preoptic area of female rats: possible involvement of opioid receptors. Neuroendocrinology 1993; 57: 236-46.
    • (1993) Neuroendocrinology , vol.57 , pp. 236-246
    • Rivest, S.1    Plotsky, P.M.2    Rivier, C.3
  • 18
    • 0015850987 scopus 로고
    • Pituitary-adrenal responsiveness during lactation in rats
    • Stern JM, Goldman L, Levine S. Pituitary-adrenal responsiveness during lactation in rats. Neuroendocrinology 1973; 12: 179-91.
    • (1973) Neuroendocrinology , vol.12 , pp. 179-191
    • Stern, J.M.1    Goldman, L.2    Levine, S.3
  • 19
    • 0026786348 scopus 로고
    • Alterations in hypothalamic-pituitary responsiveness during lactation
    • Lightman SL. Alterations in hypothalamic-pituitary responsiveness during lactation. Annals NY Acad Sci 1992; 652: 340-6.
    • (1992) Annals NY Acad Sci , vol.652 , pp. 340-346
    • Lightman, S.L.1
  • 20
    • 0026609646 scopus 로고
    • Suckling is a persistent stimulus to the adrenocortical system of the rat
    • Walker CD, Lightman SL, Steele MK, Dallman MF. Suckling is a persistent stimulus to the adrenocortical system of the rat. Endocrinology 1992; 130: 115-25.
    • (1992) Endocrinology , vol.130 , pp. 115-125
    • Walker, C.D.1    Lightman, S.L.2    Steele, M.K.3    Dallman, M.F.4
  • 21
    • 0024406287 scopus 로고
    • Reduced responses of prolactin and catecholamine to stress in the lactating rat
    • Higuichi T, Negoro H, Arita J. Reduced responses of prolactin and catecholamine to stress in the lactating rat. J Endocrinol 1989; 122: 495-8.
    • (1989) J Endocrinol , vol.122 , pp. 495-498
    • Higuichi, T.1    Negoro, H.2    Arita, J.3
  • 22
    • 0023574323 scopus 로고
    • Oxytocin responses to stress in lactating and hyperprolactinaemic rats
    • Carter DA, Lightman SL. Oxytocin responses to stress in lactating and hyperprolactinaemic rats. Neuroendocrinology 1987; 46: 532-7.
    • (1987) Neuroendocrinology , vol.46 , pp. 532-537
    • Carter, D.A.1    Lightman, S.L.2
  • 23
    • 0024514914 scopus 로고
    • Lactation inhibits stress-mediated secretion of corticosterone and oxytocin and hypothalamic accumulation of corticotropin-releasing factor and enkephalin messenger ribonucleic acids
    • Lightman SL, Young WS. Lactation inhibits stress-mediated secretion of corticosterone and oxytocin and hypothalamic accumulation of corticotropin-releasing factor and enkephalin messenger ribonucleic acids. Endocrinology 1989; 124: 2358-64.
    • (1989) Endocrinology , vol.124 , pp. 2358-2364
    • Lightman, S.L.1    Young, W.S.2
  • 24
    • 0023891990 scopus 로고
    • Expression of c-fos protein in brain: Metabolic mapping at the cellular level
    • Sagar SM, Sharp FR, Curran T. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 1988; 240: 1328-31.
    • (1988) Science , vol.240 , pp. 1328-1331
    • Sagar, S.M.1    Sharp, F.R.2    Curran, T.3
  • 25
    • 0030992939 scopus 로고    scopus 로고
    • Lactation reduces Fos induction in the paraventricular and supraoptic nuclei of the hypothalamus after urethane administration in rats
    • sous presse
    • Woodside B, Amir S. Lactation reduces Fos induction in the paraventricular and supraoptic nuclei of the hypothalamus after urethane administration in rats. Brain Res 1997 (sous presse).
    • (1997) Brain Res
    • Woodside, B.1    Amir, S.2
  • 26
    • 0027935381 scopus 로고
    • Lactation-induced deficits in NMDA receptor-mediated cortical and hippocampal activation: Changes in NMDA receptor gene expression and brain stem activation
    • Abbud R, Hoffman GE, Smith MS. Lactation-induced deficits in NMDA receptor-mediated cortical and hippocampal activation: changes in NMDA receptor gene expression and brain stem activation. Mol Brain Res 1994; 25: 323-32.
    • (1994) Mol Brain Res , vol.25 , pp. 323-332
    • Abbud, R.1    Hoffman, G.E.2    Smith, M.S.3
  • 27
    • 0029070711 scopus 로고
    • Modifications neuroendocriniennes reliées à l'activité de l'axe corticotrope an cours de la lactation ehez le rat
    • Walker CD. Modifications neuroendocriniennes reliées à l'activité de l'axe corticotrope an cours de la lactation ehez le rat. Ann Endocrinol 1995; 56: 169-72.
    • (1995) Ann Endocrinol , vol.56 , pp. 169-172
    • Walker, C.D.1
  • 28
    • 0023926168 scopus 로고
    • Factors influencing maternal responsiveness in humans: Usefulness of an animal model
    • Fleming AS, Corter C. Factors influencing maternal responsiveness in humans: usefulness of an animal model. Psychoneuroendocrinology 1988; 13: 189-212.
    • (1988) Psychoneuroendocrinology , vol.13 , pp. 189-212
    • Fleming, A.S.1    Corter, C.2
  • 29
    • 0022361543 scopus 로고
    • Reduced fearfulness in the lactating rat
    • Hard E, Hansen S. Reduced fearfulness in the lactating rat. Physiol Behav 1985; 35: 641-3.
    • (1985) Physiol Behav , vol.35 , pp. 641-643
    • Hard, E.1    Hansen, S.2
  • 30
    • 0029125282 scopus 로고
    • Lactation-induced changes in behavioral and hormonal stress responses to the forced swim test in rats
    • Walker CD, Trottier G, Rochford J, Lavallée D. Lactation-induced changes in behavioral and hormonal stress responses to the forced swim test in rats. J Neuroendocrinol 1995; 7: 615-22.
    • (1995) J Neuroendocrinol , vol.7 , pp. 615-622
    • Walker, C.D.1    Trottier, G.2    Rochford, J.3    Lavallée, D.4
  • 31
    • 17544389866 scopus 로고    scopus 로고
    • Neuroendocrinologv of the mother-child interaction
    • Uvnas-Moberg K. Neuroendocrinologv of the mother-child interaction. Trends Endocrinol Metab 1996; 7: 126-31.
    • (1996) Trends Endocrinol Metab , vol.7 , pp. 126-131
    • Uvnas-Moberg, K.1
  • 32
    • 0023258346 scopus 로고
    • Structural plasticity in the rat supraoptic nucleus during gestation, post-partum lactation and suckling-induced pseudogestation and lactation
    • Montagnese CM, Poulain DA, Vincent JD, Theodosis DT. Structural plasticity in the rat supraoptic nucleus during gestation, post-partum lactation and suckling-induced pseudogestation and lactation. J Endocrinol 1987; 115: 97-105.
    • (1987) J Endocrinol , vol.115 , pp. 97-105
    • Montagnese, C.M.1    Poulain, D.A.2    Vincent, J.D.3    Theodosis, D.T.4
  • 34
    • 0028133308 scopus 로고
    • Involvement of the bed nucleus of the stria terminalis in tonic regulation of paraventricular hypothalamic CRH and AVP mRNA expression
    • Herman JP, Cullinan WE, Watson SJ. Involvement of the bed nucleus of the stria terminalis in tonic regulation of paraventricular hypothalamic CRH and AVP mRNA expression. J Neuroendocrinol 1994; 6: 433-42.
    • (1994) J Neuroendocrinol , vol.6 , pp. 433-442
    • Herman, J.P.1    Cullinan, W.E.2    Watson, S.J.3
  • 35
    • 0002632903 scopus 로고
    • Development of pain pathways and mechanisms
    • Anand KJS, McGrath PJ, eds. Amsterdam: Elsevier
    • Fitzgerald M. Development of pain pathways and mechanisms. In: Anand KJS, McGrath PJ, eds. Pain in neonates. Amsterdam: Elsevier, 1993: 19-37.
    • (1993) Pain in Neonates , pp. 19-37
    • Fitzgerald, M.1
  • 36
    • 0027230454 scopus 로고
    • Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat
    • Bayer SA, Altman J, Russo RJ, Zhang X. Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat. Neurotoxicology 1993; 14: 83-144.
    • (1993) Neurotoxicology , vol.14 , pp. 83-144
    • Bayer, S.A.1    Altman, J.2    Russo, R.J.3    Zhang, X.4
  • 37
    • 0028147753 scopus 로고
    • Early relationships as regulators of infant physiology and behavior
    • Hofer MA. Early relationships as regulators of infant physiology and behavior. Acta Pediatr 1994; 397 (suppl): 9-18.
    • (1994) Acta Pediatr , vol.397 , Issue.SUPPL. , pp. 9-18
    • Hofer, M.A.1
  • 38
    • 0023879582 scopus 로고
    • Psychoendocrine aspects of mother-infant relationships in nonhuman primates
    • Levine S, Wiener SG. Psychoendocrine aspects of mother-infant relationships in nonhuman primates. Psychoneuroenedocrinology 1988; 13: 143-54.
    • (1988) Psychoneuroenedocrinology , vol.13 , pp. 143-154
    • Levine, S.1    Wiener, S.G.2
  • 39
    • 0000762135 scopus 로고
    • Critical periods, stimulus input, and emotional reactivity: A theory of infantile stimulation
    • Denenberg VH. Critical periods, stimulus input, and emotional reactivity: a theory of infantile stimulation. Psychol Rev 1964; 71: 335-51.
    • (1964) Psychol Rev , vol.71 , pp. 335-351
    • Denenberg, V.H.1
  • 40
    • 0023877370 scopus 로고
    • Postnatal randling attenuates neuroendocrine, anatomical, and cognitive impairments related to the aged hippocampus
    • Meaney MJ, Aitken DH, Bhatnagar S, Van Berkel C, Sapolsky RM. Postnatal randling attenuates neuroendocrine, anatomical, and cognitive impairments related to the aged hippocampus. Science 1988; 238: 766-8.
    • (1988) Science , vol.238 , pp. 766-768
    • Meaney, M.J.1    Aitken, D.H.2    Bhatnagar, S.3    Van Berkel, C.4    Sapolsky, R.M.5
  • 42
    • 0029887952 scopus 로고    scopus 로고
    • Infants and young children in orphanages: One view from pediatrics and child psychiatry
    • Frank DA, Klass PE, Earls F, Eisenberg L. Infants and young children in orphanages: one view from pediatrics and child psychiatry. Pediatrics 1996; 97: 569-78.
    • (1996) Pediatrics , vol.97 , pp. 569-578
    • Frank, D.A.1    Klass, P.E.2    Earls, F.3    Eisenberg, L.4
  • 43
    • 0029909534 scopus 로고    scopus 로고
    • Small Refugees suffer the effects of early neglect
    • Holden C. Small Refugees suffer the effects of early neglect. Science 1996; 274: 1076-7.
    • (1996) Science , vol.274 , pp. 1076-1077
    • Holden, C.1
  • 44
    • 0029061902 scopus 로고
    • Effects of chemical sympathectomy and maternal separation on neonatal adrenocortical stress responses and adrenal sensitivity to ACTH
    • Walker CD. Effects of chemical sympathectomy and maternal separation on neonatal adrenocortical stress responses and adrenal sensitivity to ACTH. Am J Physiol 1995; 268: R1281-8.
    • (1995) Am J Physiol , vol.268
    • Walker, C.D.1
  • 46
    • 0030014898 scopus 로고    scopus 로고
    • Neonatal maternally deprived rats have as adults elevated basal pituitary-adrenal activity and enhanced susceptibility to apomorphine
    • Rots NY, deJong J, Workel JO, Levine S, Cools AR, DeKloet ER. Neonatal maternally deprived rats have as adults elevated basal pituitary-adrenal activity and enhanced susceptibility to apomorphine. J Neuroendocrinol 1996; 8: 501-6.
    • (1996) J Neuroendocrinol , vol.8 , pp. 501-506
    • Rots, N.Y.1    DeJong, J.2    Workel, J.O.3    Levine, S.4    Cools, A.R.5    DeKloet, E.R.6
  • 47
    • 0027195888 scopus 로고
    • Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence content and stress-induced release in adult rats
    • Plotsky PM, Meaney MJ. Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence content and stress-induced release in adult rats. Mol Brain Res 1993; 18: 195-200.
    • (1993) Mol Brain Res , vol.18 , pp. 195-200
    • Plotsky, P.M.1    Meaney, M.J.2
  • 48
    • 0026844944 scopus 로고
    • The stressfulness of separation among nine-month-old infants: Effects of social context variables and infant temperament
    • Gunnar MR, Larson MC, Hertsgaard L, Harris ML, Brodersen L. The stressfulness of separation among nine-month-old infants: effects of social context variables and infant temperament. Child Dev 1992; 63: 290-303.
    • (1992) Child Dev , vol.63 , pp. 290-303
    • Gunnar, M.R.1    Larson, M.C.2    Hertsgaard, L.3    Harris, M.L.4    Brodersen, L.5
  • 49
    • 0029928064 scopus 로고    scopus 로고
    • Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult non human primates exposed to early-life Stressors: Implications for the pathophysiology of mood and anxiety disorders
    • Coplan JD, Andrews MW, Rosenblum LA, Owens MJ, Friedman S, German JM, Nemeroff CB. Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult non human primates exposed to early-life Stressors: implications for the pathophysiology of mood and anxiety disorders. Proc Natl Acad Sci USA 1996; 93: 1619-23.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1619-1623
    • Coplan, J.D.1    Andrews, M.W.2    Rosenblum, L.A.3    Owens, M.J.4    Friedman, S.5    German, J.M.6    Nemeroff, C.B.7
  • 50
    • 4243663043 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal responses to stress in neonatally handled and nonhandled rats: Differences in facilitatory and inhibitory neural pathways
    • McCarty R, Aguilera G, Sabban E, Kvetnansky R, eds. New York: Gordon and Breach Science
    • Bhatnagar S, Shanks N, Plotsky PM, Meaney MJ. Hypothalamic-pituitary-adrenal responses to stress in neonatally handled and nonhandled rats: differences in facilitatory and inhibitory neural pathways. In: McCarty R, Aguilera G, Sabban E, Kvetnansky R, eds. Stress: molecular, genetic and neurobiological advances. New York: Gordon and Breach Science, 1996, 1-24.
    • (1996) Stress: Molecular, Genetic and Neurobiological Advances , pp. 1-24
    • Bhatnagar, S.1    Shanks, N.2    Plotsky, P.M.3    Meaney, M.J.4
  • 51
    • 0000741045 scopus 로고
    • Postnatal handling increases hippocampal type II, glucocorticoid receptors and enhances adrenocortical negative feedback efficacy in the rat
    • Meaney MJ, Aitken DH, Sharma S, Viau V, Sarrieau A. Postnatal handling increases hippocampal type II, glucocorticoid receptors and enhances adrenocortical negative feedback efficacy in the rat. Neuroendocrinology 1989; 51: 507-604.
    • (1989) Neuroendocrinology , vol.51 , pp. 507-604
    • Meaney, M.J.1    Aitken, D.H.2    Sharma, S.3    Viau, V.4    Sarrieau, A.5
  • 52
    • 0025804787 scopus 로고
    • The role of the hippocampus in feedback regulation of the hypothalamus pituitary adrenal axis
    • Jacobson L, Sapolsky RM. The role of the hippocampus in feedback regulation of the hypothalamus pituitary adrenal axis. Endocrinol Rev 1991; 12: 118-33.
    • (1991) Endocrinol Rev , vol.12 , pp. 118-133
    • Jacobson, L.1    Sapolsky, R.M.2
  • 53
    • 0023473485 scopus 로고
    • Postnatal handling reduces novelty induced fear and increases 3H-flunitrazepam binding in rat brain
    • Bodnoff SR, Suryani-Cadotte BE, Quirion R, Meaney MJ. Postnatal handling reduces novelty induced fear and increases 3H-flunitrazepam binding in rat brain. Eur J Pharmacol 1987; 144: 105-7.
    • (1987) Eur J Pharmacol , vol.144 , pp. 105-107
    • Bodnoff, S.R.1    Suryani-Cadotte, B.E.2    Quirion, R.3    Meaney, M.J.4
  • 54
    • 0026663876 scopus 로고
    • Glucocorticoids and the development of neuronal function: Effects of prenatal dexamethasone exposure on central noradrenergic activity
    • Slotkin TA, Lappi SE, McCook EC, Tayyeb MI, Eylers JP, Seidler FJ. Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity. Biol Neonate 1992; 61: 326-36.
    • (1992) Biol Neonate , vol.61 , pp. 326-336
    • Slotkin, T.A.1    Lappi, S.E.2    McCook, E.C.3    Tayyeb, M.I.4    Eylers, J.P.5    Seidler, F.J.6
  • 55
    • 0021720913 scopus 로고
    • The suppression of pulsatile luteinizing hormone secretion during lactation in the rat
    • Fox SR, Smith MS. The suppression of pulsatile luteinizing hormone secretion during lactation in the rat. Endocrinology 1984; 115: 2045-51.
    • (1984) Endocrinology , vol.115 , pp. 2045-2051
    • Fox, S.R.1    Smith, M.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.