Molecular genetics of colorectal cancer

Digestion

Volumn 58, Issue , 1997, Pages 65-68

  Kim, Young S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Colorectal cancer; Familial adenomatous polyposis; Hereditary nonpolyposis colorectal cancer

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

BASE MISPAIRING; CANCER SUSCEPTIBILITY; CELL GROWTH; CELL PROLIFERATION; COLON POLYPOSIS; COLORECTAL CANCER; CONFERENCE PAPER; DNA REPAIR; FAMILIAL CANCER; GENE MUTATION; HUMAN; MALIGNANT TRANSFORMATION; MOLECULAR GENETICS; ONCOGENE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0030966558     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000201531     Document Type: Article

References (14)

1. Vogelstein B, Fearon HR, Hamilton SR. et al.: Genetic alterations during colorectal tumor development. N Engl J Med 1988;319:525-532.
2. Miyaki M, Komshi M, Kikuchi-Yamoshita R. et al.: Characteristics of somatic mutations of the adenomatous polyposis coli gene in colorectal tumors. Cancer Res 1994:54:3011-3020.
3. Lepperl M, Burt R, Hughes JP. et al.: Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps. N Engl J Med 1990:322: 904-908.
4. Olschwang S, Tiret A, Laurent-Puig P. et al.: Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients. Cell 1993:75:959-968.
5. Fishel R, Lescoe MK, Rao MRS, et al.: The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer cell. Cell 1993:75:1027-1038.
6. Bronncr CF, Baker SM, Morrison PT. et al. Mutations in the DNA mismatch repair gene homologue hMLHI is associated with hereditary non-polyposis colon cancer. Nature 1994; 368:258-261.
7. Nicolaides NC, Papadapoulos N, Liu B. et al.: Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994: 371:75-80.
8. Thibodeau SN, Boren G, Schaid D. et al.: Microsatellite instability in cancer of the proximal colon. Science 1993:260:816-819.
9. Markowitz S, Wang J, Myeroff L. et al.: inactivation of the type II TGF-p receptor in colon cancer cells with microsatellite instability. Science 1995:268:1336.
10. Cannon-Albright LA, Skolnick MK, Bishop DT. et al.: Common inheritance of susceptibility lo colonic adenomatous polyps and associated colorectal cancers. N Engl. J Med 1988:319:533-537.
11. St John DJ, McDermott ET, Hooper JL, et al.: Cancer risk in relatives of patients with common colorectal cancer. Ann Intern Med 1993:118: 785-790.
12. Jen J, Hoguen K, Prantadose S, et al.: Allelic loss of chromosome I8q and prognosis in colorectal cancer. N Engl J Med 1994:331:213-221.
13. Sidransky D, Tokino T, Hamilton SR: Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992:256:102-105.
14. Bresalier RS, Kim YS: Malignant neoplasms of the large intestine: in Sleisenger MIL Fordtrans JS(eds): Gastrointestinal Disease: Pathophysiology, Diagnosis and Management. Philadelphia. Saunders 1997. in press.