Chemical and biological characterization of two FK506 analogs produced by targeted gene disruption in Streptomyces sp. MA6548

Journal of Antibiotics

Volumn 50, Issue 5, 1997, Pages 418-423

  Shafiee, Ali ^a   Motamedi, Haideh ^a   Dumont, Francis J ^b   Arison, Byron H ^c   Miller, Randall R ^c  

^a Natural Products Drug Discovery   (United States)

^b Immunology Research   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; DRUG DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; TACROLIMUS;

ANIMAL CELL; ANTIBIOTIC BIOSYNTHESIS; ANTIFUNGAL ACTIVITY; ARTICLE; BACTERIUM MUTANT; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; FERMENTATION; GENE DISRUPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES;

EID: 0030966530     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.50.418     Document Type: Article

References (10)

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