A new anthracycline antibiotic, IT-62-B, converts the morphology of ras-transformed cells back to normal: Taxonomy, fermentation, isolation, structure elucidation and biological characterization

Journal of Antibiotics

Volumn 50, Issue 4, 1997, Pages 297-303

  Kawauchi, Takashi ^a   Sasaki, Toru ^a   Yoshida, Ken Ichiro ^a   Matsumoto, Hiroshi ^a   Chen, Ru Xian ^b   Huang, Ming Yu ^b   Otani, Toshio ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; DOXORUBICIN; IT 62B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC BIOSYNTHESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CELL STRAIN 3T3; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; EXPERIMENTAL NEOPLASM; FERMENTATION; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; INFRARED SPECTROMETRY; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKEMIA L 1210; LEUKEMIA P 388; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NASOPHARYNX CANCER; NONHUMAN; ONCOGENE RAS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES; T LYMPHOCYTE; TAXONOMY; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0030966519     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.50.297     Document Type: Article

References (16)

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