The optimal number of embryos to be transferred in shared oocyte donation: Walking the thin line between low pregnancy rates and multiple pregnancies

Human Reproduction

Volumn 12, Issue 4, 1997, Pages 699-702

  Yaron, Yuval ^a,b,c   Amit, Ami ^a,b   Kogosowski, Abraham ^d   Peyser, M Reuben ^a,b   David, Menachem P ^a,b   Lessing, Joseph B ^a,b  

^a Serlin Maternity Hospital   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c WAYNE STATE UNIVERSITY   (United States)

^d Institute of Medical Genetics   (Israel)

Author keywords

Embryo transfer; In vitro fertilization; Multiple pregnancies; Oocyte donation

Indexed keywords

ARTICLE; EMBRYO TRANSFER; FEMALE; FEMALE INFERTILITY; HUMAN; MAJOR CLINICAL STUDY; MULTIPLE PREGNANCY; NIDATION; OOCYTE DONATION; OVARY INSUFFICIENCY; PRACTICE GUIDELINE; PREGNANCY RATE;

EID: 0030966496     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/12.4.699     Document Type: Article

References (21)

1. Acosta, A.A., Moon, S.Y., Oehninger, S. et al. (1985) Implantation potential of each pre-embryo in multiple pregnancies obtained by in vitro fertilization seems to be different. Fertil. Steril., 50, 906-911.
2. Ahuja, K.K., Simons, E.G., Fiamanya, W. et al. (1996) Egg-sharing in assisted conception: ethical and practical considerations. Hum. Reprod., 11, 1126-1131.
3. Cohen, J., de Mouzon, J. and Lancaster, P. (1993) World Collaborative Report 1991. Proceedings of the VIIIth World Congress on In Vitro Fertilization and Alternate Assisted Reproduction, September 12-15, 1993, Kyoto, Japan.
4. Dawson, K.J., Rutherford, A.J., Margara, R.A. et al. (1991) Reducing triplet pregnancies following in vitro fertilization. Lancet, 337, 1543-1544.
5. Evans, M.I., Dommergues, M., Wapner, R.J. et al. (1996) International collaborative experience of 1789 patients having multifetal pregnancy reduction: a plateauing of risks and outcomes. J. Society. Gynecol. Invest., 3, 20-22.
6. Forman, R., Fries, N., Testart, J. et al. (1988) Evidence for an adverse effect of elevated serum estradiol concentration on embryo implantation. Fertil. Steril., 49, 118-122.
7. Kogosowski, A., Amit, A., Barak, Y. et al. (1992) High initial values of β-subunits of human chorionic gonadotropin in ovum donation pregnancies indicate better implantation. Fertil. Steril., 57, 1354-1355.
8. Legro, R.S., Wong, I.L., Paulson, R.J. et al. (1995) Multiple implantation after oocyte donation: a frequent but inefficient event. Fertil. Steril., 63, 849-853.
9. Levran, D., Ben-Shlomo, I., Dor, J. et al. (1991) Aging of endometrium and oocytes: observations on conception and abortion rates in an egg donation model. Fertil. Steril., 56, 1091-1094.
10. Medical Research International, Society for Assisted Reproductive Technology (SART), The American Fertility Society (1992) In vitro fertilization-embryo transfer in the United States: 1990 results from the IVF-ET Registry. Fertil. Steril., 57, 15-24.
11. Muasher, S., Wilkes, C., Garcia, J.E. et al. (1984) Benefits and risks of multiple transfer with in vitro fertilization (Letter). Lancet, i, (8376), 570.
12. Navot, D., Laufer, N., Kopolovic, J. et al. (1986) Artificially induced endometrial cycles and establishment of pregnancies in the absence of ovaries. N. Engl. J. Med., 314, 806-811.
13. Paulson, R.J., Sauer, M.V., Lobo, R.A. (1990) Embryo implantation after human in vitro fertilization: importance of endometrial receptivity. Fertil. Steril., 53, 870-874.
14. Rosenwaks, Z. (1987) Donor eggs: their application in modern reproductive technologies. Fertil. Steril., 47, 895-909.
15. Sauer, M.V., Paulson, R.J., Macaso, T.M. et al. (1991) Oocyte and pre-embryo donation to women with ovarian failure: an extended clinical trial. Fertil. Steril., 55, 39-43.
16. Society for Assisted Reproductive Technology, American Society for Reproductive Medicine (1996) Assisted reproductive technology in the United States and Canada: 1994 results generated from the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry. Fertil. Steril., 66, 697-705.
17. Speirs, A.L., Lopata, A., Gronow, M.J. et al (1983) Analysis of the benefits and risks of multiple embryo transfer. Fertil. Steril., 39, 468-471.
18. Tucker, M.J., Kort, H.I., Massey, J.B. et al. (1991) How many IVF embryos to transfer. Lancet, 337, 975-976.
19. Vauthier-Brouzes, D., Lefebvre, G., Lesourd, S. et al. (1994) How many embryos should be transferred in in vitro fertilization? A prospective randomized trial. Fertil. Steril., 62, 339-342.
20. Wood, C., McMaster, R., Rennie, G. et al. (1985) Factors influencing pregnancy rates following in vitro fertilization and embryo transfer. Fertil. Steril., 43, 245-250.
21. Yaron, Y., Botchan, A., Amit, A. et al (1993) Endometrial receptivity: the age-related decline in pregnancy rates and the effect of ovarian function. Fertil Steril., 60, 314-318.