Role of repetitive antigen patterns for induction of antibodies against antibodies

Journal of Experimental Medicine

Volumn 185, Issue 10, 1997, Pages 1785-1792

  Fehr, Thomas ^a   Bachmann, Martin F ^a,d   Bucher, Etienne ^a   Kalinke, Ulrich ^a   Di Padova, Franco E ^b   Lang, Alois B ^c   Hengartner, Hans ^a   Zinkernagel, Rolf M ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Berna Biotech AG   (Switzerland)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN ANTIBODY;

ANTIBODY RESPONSE; ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ARTICLE; AUTOIMMUNITY; CELLULAR IMMUNITY; IMMUNOPATHOGENESIS; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; AUTOANTIBODIES; CELL LINE; CRICETINAE; EPITOPES; IMMUNOGLOBULIN ALLOTYPES; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN IDIOTYPES; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; O ANTIGENS; PSEUDOMONAS AERUGINOSA; RECOMBINANT FUSION PROTEINS; VESICULAR STOMATITIS-INDIANA VIRUS; VIRAL ENVELOPE PROTEINS;

EID: 0030965840     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.10.1785     Document Type: Article

References (51)

1. Nemazee, D.A. 1985. Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice. J. Exp. Med. 161:242-256.
2. Coulie, P.G., and J. Van Snick. 1985. Rheumatoid factor (RF) production during anamnestic immune responses in the mouse III. Activation of RF precursor cells is induced by their interaction with immune complexes and carrier-specific helper T cells. J. Exp. Med. 161:88-97.
3. Holmdahl, R., C. Nordling, K. Rubin, A. Tarkowski, and L. Klareskog. 1986. Generation of monoclonal rheumatoid factors after immunization with collagen II-anti-collagen II immune complexes. An anti-idiotypic antibody to anti-collagen II is also a rheumatoid factor. Scand. J. Immunol. 24:197-203.
4. Kanoh, M., S. Utsumi, and T. Hino. 1986. Induction of rheumatoid factors in mice by immune complexes of bacterial lipopolysaccharide with mouse IgG antibody. Eur. J. Immunol. 16:63-68.
5. Spring, S.B., and A. Nisonoff. 1974. Allotypic markers on Fab fragments of mouse immunoglobulins. J. Immunol. 113: 470-478.
6. Schrohenloher, R.E., and W.J. Koopman. 1993. Rheumatoid factor. In Arthritis and Allied Conditions. D.J. McCarty and W.J. Koopman, editors. Lea and Febiger, Philadelphia/ London. 861-876.
7. Carson, D.A. 1993. Rheumatoid factor. In Textbook of Rheumatology. W.N. Kelley, E.D. Harris, S. Ruddy, and C.B. Sledge, editors. W.B. Saunders Company, Philadelphia. 155-163.
8. Carson, D.A., P.P. Chen, and T.J. Kipps. 1991. New roles for rheumatoid factor. J. Clin. Invest. 87:379-383.
9. Van Snick, J.L., E. Van Roost, B. Markowetz, C.L. Cambiaso, and P.L. Masson. 1978. Enhancement by IgM rheumatoid factor of in vitro ingestion by macrophages and in vivo clearance of aggregated IgG or antigen-antibody complexes. Eur. J. Immunol. 8:279-285.
10. Roosnek, E., and A. Lanzavecchia. 1991. Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells. J. Exp. Med. 173:487-489.
11. Notkins, A.L. 1971. Infectious virus-antibody complexes: interaction with anti-immunoglobulins, complement, and rheumatoid factor. J. Exp. Med. 134(Suppl):41s-51s.
12. Clarkson, A.B., Jr., and G.H. Mellow. 1981. Rheumatoid factor-like immunoglobulin M protects previously uninfected rat pups and dams from Trypanosoma lewisi. Science (Wash. DC). 214:186-188.
13. Zvaifler, N.J. 1973. The immunopathology of joint inflammation in rheumatoid arthritis. Adv. Immunol. 16:265-336.
14. del Puente, A., W.C. Knowler, D.J. Pettitt, and P.H. Bennett. 1988. The incidence of rheumatoid arthritis is predicted by rheumatoid factor titer in a longitudinal population study. Arthritis Rheum. 31:1239-1244.
15. Hughes, G.R.V. 1987. Connective Tissue Diseases. Blackwell Scientific Publications, Oxford. 1-286.
16. Winchester, R.J., V. Agnello, and H.G. Kunkel. 1970. Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis. Partial characterization and relationship to lowered complement levels. Clin. Exp. Immunol. 6:689-706.
17. Jerne, N.K. 1974. Towards a network theory of the immune system. Ann. Inst. Pasteur Immunol. 125C:373-389.
18. Eichmann, K. 1978. Expression and function of idiotypes on lymphocytes. Adv. Immunol. 26:195-254.
19. Binz, H., and H. Wigzell. 1977. Antigen-binding idiotypic T lymphocyte receptors. Contemp. Topics Immunobiol. 7:113.
20. Pereira, P., A. Bandeira, A. Coutinho, M.-A. Marcos, M. Toribio, and C. Martinez-A. 1989. V-region connectivity in T cell repertoires. Annu. Rev. Immunol. 7:209-249.
21. Bachmann, M.F., H. Hengartner, and R.M. Zinkernagel. 1995. T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction? Eur. J. Immunol. 25:3445-3451.
22. Bachmann, M.F., C. Bast, H. Hengartner, and R.M. Zinkernagel. 1994. Immunogenicity of a viral model vaccine after different inactivation procedures. Med. Microbiol. Immunol. 183: 95-104.
23. Matsuura, Y., R.D. Possee, H.A. Overton, and D.H.L. Bishop. 1987. Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins. J. Gen. Virol. 68:1233-1250.
24. Di Padova, F.E., H. Brade, G.R. Barclay, I.R. Poxton, E. Liehl, E. Schuetze, H.P. Kocher, G. Ramsay, M.H. Schreier, D.B. McClelland et al. 1993. A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides. Infect. Immun. 61:3863-3872.
25. Lang, A.B., U. Bruderer, E. Fuerer, J.W. Larrick, and S.J. Cryz. 1990. Immunoprotective capacities of human and murine monoclonal antibodies recognizing serotype-specific and common determinants of gram-negative bacteria. In Therapeutic Monoclonal Antibodies. C.A.K. Borrebaeck and J.W. Larrick, editors. Stockton Press, New York. 223-234.
26. Fehr, T., M.F. Bachmann, H. Bluethmann, H. Kikutani, H. Hengartner, and R.M. Zinkernagel. 1996. T-independent activation of B cells by Vesicular stomatitis virus: no evidence for the need of a second signal. Cell. Immunol. 168:184-192.
27. Traunecker, A., J. Schneider, H.R. Kiefer, and K. Karjalainen. 1989. Highly efficient neutralization of HIV with recombinant CD4-immunoglobulin molecules. Nature (Lond.). 339:68-70.
28. Bachmann, M.F., U. Hoffmann Rohrer, T.M. Kündig, K. Bürki, H. Hengartner, and R.M. Zinkernagel. 1993. The influence of antigen organization on B cell responsiveness. Science (Wash. DC). 262:1448-1451.
29. 28a. Petri, W.A., Jr., and R.R. Wagner. 1979. Reconstitution into liposomes of the glycoprotein of vesicular stomatitis virus by detergent dialysis. J. Biol Chem. 254:4313-4316.
30. Wagner, R.R. 1987. The Rhabdoviruses. Plenum Press, New York. 1-544.
31. Kalinke, U., E.M. Bucher, B. Ernst, A. Oxenius, H.P. Roost, S. Geley, R. Kofler, R.M. Zinkernagel, and H. Hengartner. 1996. The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus (VSV). Immunity. 5:639-652.
32. Murakami, M., T. Tsubata, M. Okamoto, A. Shimizu, S. Kumagai, H. Imura, and T. Honjo. 1992. Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice. Nature (Lond.). 357:77-80.
33. Nemazee, D.A., and K. Bürki. 1989. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature (Lond.). 337:562-566.
34. Hartley, S.B., J. Crosbie, R. Brink, A.B. Kantor, A. Basten, and C.C. Goodnow. 1991. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature (Lond.). 353:765-769.
35. Tighe, H., P. Heaphy, S. Baird, W.O. Weigle, and D.A. Carson. 1995. Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice. J. Exp. Med. 181:599-606.
36. Feldmann, M., and A. Basten. 1971. The relationship between antigenic structure and the requirement for thymusderived cells in the immune response. J. Exp. Med. 134: 103-119.
37. Dintzis, R.Z., M.H. Middleton, and H.M. Dintzis. 1985. Inhibition of anti-DNP antibody formation by high doses of DNP-polyacrylamide molecules; effects of hapten density and hapten valence. J. Immunol. 135:423-427.
38. Schödel, F., D. Peterson, J. Zheng, J.E. Jones, J.L. Hughes, and D.R. Milich. 1993. Structure of hepatitis B virus core and e-antigen. A single precore amino acid prevents nucleocapsid assembly. J. Biol. Chem. 268:1332-1337.
39. Burns, W.H., L.C. Billups, and A.L. Notkins. 1975. Thymus dependence of viral antigens. Nature (Lond.). 256:654-656.
40. Szomolanyi-Tsuda, E., and R.M. Welsh. 1996. T cell-independent antibody-mediated clearance of polyoma virus in T cell-deficient mice. J. Exp. Med. 183:403-411.
41. Barington, T., L. Hougs, L. Juul, H.O. Madsen, L.P. Ryder, C. Heilmann, and A. Svejgaard. 1996. The progeny of a single virgin B cell predominates the human recall B cell response to the capsular polysaccharide of Haemophilus influenzae type b. J. Immunol. 157:4016-4027.
42. Fazekas, G., E. Rajnavolgyi, I. Kurucz, E. Sintar, K. Kiss, G. Laszlo, and J. Gergely. 1990. Isolation and characterization of IgG2a-reactive autoantibodies from influenza virus-infected BALB/c mice. Eur. J. Immunol. 20:2719-2729.
43. Williams, R.C. 1988. Rheumatoid factors in subacute bacterial endocarditis and other infectious diseases. Scand. J. Rheumatol. 75 (Suppl.):300-308.
44. Ferraro, A.S., and M.M. Newkirk. 1993. Correlative studies of rheumatoid factors and anti-viral antibodies in patients with rheumatoid arthritis. Clin. Exp. Immunol. 92:425-431.
45. Tsuchiya, N., R.C. Williams, Jr., and L.M. Hutt-Fletcher. 1990. Rheumatoid factors may bear the internal image of the Fc gamma-binding protein of herpes simplex virus type 1. J. Immunol. 144:4742-4748.
46. Schuval, S.J., V.R. Bonagura, and N.T. Ilowite. 1993. Rheumatologic manifestations of pediatric human immunodeficiency virus infection. J. Rheumatol. 20:1578-1582.
47. Medina-Rodriguez, F., C. Guzman, L.J. Jara, C. Hermida, D. Albourek, H. Cervera, J.M. Miranda, and A. Fraga. 1993. Rheumatic manifestations in human immunodeficiency virus positive and negative individuals: a study of 2 populations with similar risk factors. J. Rheumatol. 20:1880-1884.
48. Chavez-Legaspi, M., A. Gomez-Vazquez, and I. Garcia-De La Torre. 1985. Study of rheumatic manifestations and serologic abnormalities in patients with lepromatous leprosy. J. Rheumatol. 12:738-741.
49. Kardjito, T., and J.M. Grange. 1980. Immunological and clinical features of smear-positive pulmonary tuberculosis in East Java. Tubercle. 61:231-238.
50. Holmdahl, R., M. Andersson, T.J. Goldschmidt, K. Gustafsson, L. Jansson, and J.A. Mo. 1990. Type II collagen autoimmunity in animals and provocations leading to arthritis. Immunol. Rev. 118:193-232.
51. Izui, S., and R.A. Eisenberg. 1980. Circulating anti-DNA-rheumatoid factor complexes in MRL/1 mice. Clin. Immunol. Immunopathol. 15:536-551.