Indium-labeled white blood cells apheresed from donors receiving G-CSF localize to sites of inflammation when infused into allogeneic bone marrow transplant recipients

Bone Marrow Transplantation

Volumn 19, Issue 8, 1997, Pages 809-812

  Adkins, D ^a   Goodgold, H ^b   Hendershott, L ^b   Johnston, M ^b   Cravens, D ^b   Spitzer, G ^c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b S LOUIS UNIV HLTH SCIENCES CENTER   (United States)

^c LDS HOSPITAL   (United States)

Author keywords

G CSF; Granulocyte transfusions; Indium labeled

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INDIUM;

ADOLESCENT; ADULT; AGED; APHERESIS; ARTICLE; CECUM; CELL CULTURE; CELL MIGRATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; DIARRHEA; GRANULOCYTE TRANSFUSION; HUMAN; ILEUM; INFECTION; INFLAMMATION; LEUKOCYTE; MUCOSA INFLAMMATION; NASOPHARYNX; NEUTROPHIL; OROPHARYNX; PRIORITY JOURNAL; SCINTIGRAPHY; TISSUE INJURY;

EID: 0030965312     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1700749     Document Type: Article

References (23)

1. Bensinger WI, Price TH, Dale DC et al. The effects of daily recombinant human granulocyte colony stimulating factor administration on normal granulocyte donors undergoing leukapheresis. Blood 1993; 81: 1883-1888.
2. Caspar C, Seger R, Burger J, Gmur J. Effective stimulation of donors for granulocyte transfusions with recombinant methionyl granulocyte colony-stimulating factor. Blood 1993; 81: 2866-2871.
3. Macpherson J, Nusbacher J, Bennett J. The acquisition of granulocytes by leukapheresis: a comparison of continuous flow centrifugation and filtration leukapheresis in normal and corticosteroid stimulated donors. Transfusion 1976; 16: 221-228.
4. Shoji M, Vogler W. Effects of hydrocortisone on the yield and bactericidal function of granulocytes collected by continuous-flow centrifugation. Blood 1974; 44: 435-443.
5. Begley CG, Lopez AF, Nicola NA et al. Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony stimulating factors. Blood 1986; 68: 162-166.
6. Colotta F, Re F, Polentarutti N et al. Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 1992; 80: 2012-2020.
7. Liles WC, Rodger ER, Dale DC. In vivo administration of granulocyte colony-stimulating factor (G-CSF) to normal human subjects: priming of the respiratory burst and inhibition of apoptosis in neutrophils. Blood 1994; 84: 24a (Abstr.).
8. Colotta F, Re F, Mantovani A. Granulocyte transfusions from granulocyte colony-stimulating factor-treated donors: also a question of cell survival? Blood 1993; 81: 2258 (letter).
9. Strauss RG. Therapeutic granulocyte transfusions in 1993. Blood 1993; 81: 1675-1678.
10. Adkins D, Johnston M, Cravens D et al. Significant prolonged increments in the absolute neutrophil count (ANC) of allogeneic bone marrow transplant (Allo-BMT) recipients (R) occurs with prophylactic neutrophil infusions (INF) obtained from HLA matched donors (D) receiving granulocyte colony stimulating factor (G-CSF). Proceedings of the Thirty-seventh Annual Meeting of the American Society of Hematology. Blood 1995; 86: 2317 (Abstr.).
11. Smith WB, Gamble JR, Vadas MA. The role of granulocyte-macrophage and granulocyte colony-stimulating factors in neutrophil transendothelial migration: comparison with interleukin-8. Exp Hematol 1994; 22: 329-334.
12. Schiffer CA. Prevention of alloimmunization against platelets. Blood 1991; 77: 1-4.
13. Goodgold HM, Genticore RC, Hendershott L et al. Significance of diffuse cardiac activity on In-111 labeled leukocyte scans. Ear J Nucl Med 1986; 12: 271-273.
14. Chow HS, Sarpel SC, Epstein RB. Pathophysiology of Candida albicans meningitis in normal, neutropenic, and granulocyte transfused dogs. Blood 1980; 55: 546-551.
15. Appelbaum FR, Norton L, Graw RG Jr. Migration of transfused granulocytes in leukopenic dogs. Blood 1977; 49: 483-488.
16. Price TH. Kinetics of transfused neutrophils. In: Vogler WR (ed.) Cytapheresis and Plasma Exchange: Clinical Indications. Alan R Liss: New York, 1982, p 19.
17. Kauder E, Boggs DR, Athens JW et al. Leukokinetic studies. XII. Kinetic studies of normal isologous neutrophilic granulocytes transfused into normal subjects. Proc Soc Exp Biol Med 1965; 120: 595-599.
18. 111indium-labeled granulocytes to sites of infection. New Engl J Med 1981; 304: 586-589.
19. Dutcher JP, Schiffer CA, Johnston GS et al. Alloimmunization prevents the migration of transfused indium-111-labeled granulocytes to sites of infection. Blood 1983; 62: 354-360.
20. Appelbaum FR, Trapani RJ, Graw RG. Consequences of prior alloimmunization during granulocyte transfusion. Transfusion 1977; 17: 460-464.
21. Kerst JM, De Haas M, van der Schoot CE et al. Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells. Blood 1993; 82: 3265-3269.
22. Ohsaka A, Kitagawa S, Sakamoto S et al. In vivo activation of human neutrophil functions by administration of recombinant human granulocyte colony-stimulating factor in patients with malignant lymphoma. Blood 1989; 74: 2743-2748.
23. Yong KL, Lined DC. Differential effects of granulocyte and granulocyte-macrophage colony stimulating factors (G- and GM-CSF) on neutrophil adhesion in vitro and in vivo. Ear J Haematol 1992; 49: 251-256.