The expression of the Epstein-Barr virus nuclear antigen (EBNA-1) in oral hairy leukoplakia

Oral Diseases

Volumn 3, Issue SUPPL. 1, 1997, Pages

  Cruchley, A T ^a   Murray, P G ^b   Niedobitek, G ^b   Reynolds, G M ^b   Williams, D M ^a   Young, L S ^b  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

EBNA 1; EBV; Latency; Oral hairy leukoplakia

Indexed keywords

CELL NUCLEUS ANTIGEN; GENE PRODUCT; MONOCLONAL ANTIBODY;

ANTIGEN EXPRESSION; BIOPSY; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; EPSTEIN BARR VIRUS; HUMAN; HUMAN TISSUE; LATENT VIRUS INFECTION; LEUKOPLAKIA; MOUTH MUCOSA; PRIORITY JOURNAL; VIRUS GENE; VIRUS REPLICATION;

EID: 0030965210     PISSN: 1354523X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1601-0825.1997.tb00354.x     Document Type: Conference Paper

References (16)

1. Brooks L, Yao QY, Rickinson AB et al (1992). Epstein-Barr virus latent gene transcription in nasopharyngeal carconoma cells: coexpression of EBNA-1, LMP-1 and LMP-2 transcripts. Am J Pathol 140: 879-887.
2. Dawson CW, Eliopoulos AG, Dawson J et al (1995). BHRF1, a viral homologue of the Bcl-2 oncogene, disturbs epithelial cell differentiation Oncogene 10, 69-77.
3. Dawson CW, Rickinson AB, Young LS (1990). Epstein-Bair virus latent membrane protein inhibits human epithelial cell differentiation. Nature 344: 777-780.
4. Grasser FA, Murray PG, Kremmer E et al (1994). Monoclonal antibodies directed agianst the Epstein-Barr virus encoded nuclear antigen 1: immunohistological detection of EBNA1 in the malignant cells in Hodgkin's Disease. Blood 84: 3792-3798.
5. Greenspan JS, Greenspan D, Lennette ET et al (1985). Replication of Epstein-Barr virus within the epithelial cells of oral 'hairy' leukoplakia, an AIDS-associated lesion. New Eng J Med 313: 1564-1571.
6. Imai S, Koizumi S, Suguira M et al (1994). Gastric carcinoma: monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein. Proc Nat Acad Sci USA 91: 9131-9135.
7. Kieff E, Liebowitz D (1990). Epstein-Barr virus and its replication. In: Fields BN, Knipe DM, eds. Virology, Raven Press: New York, pp 1889-1920.
8. Li QX, Young LS, Niedobitek G et al (1992). Epstein-Barr virus infection and replication in a human epithelial cell system. Nature 356: 347-350.
9. Murray PG, Niedobitek G, Kremmer E et al (1996). In situ detection of the Epstein-Barr virus encoded nuclear antigen-1 in oral hairy leukoplakia and virus associated carcinomas. J Pathol 178: 44-47.
10. Niedobitek G, Agathanngelou A, Rowe M et al (1995). Heterogenous expression of EBV latent proteins in endemic Burkitt's lymphoma. Blood 86: 659-665.
11. Niedobitek G, Young LS, Lau R et al (1991). Epstein-Barr virus infection in oral hairy leukoplakia: virus replication in the absence of a detectable latent phase. J Gen Virol 72: 3035-3046.
12. Sandvej K, Krenacs L, Hamilton-Dutoit SJ et al (1992). Epstein-Barr virus latent and replicative gene expression in oral hairy leukoplakia. Histopathology 20: 387-395.
13. Thomas JA, Felix DH, Wray D et al (1991). Epstein-Barr virus gene expression and epithelial cell differentiation in oral hairy leukoplakia. Am J Pathol 139: 1369-1380.
14. Wilson JB, Levine AJ (1992). The oncogenic potential of Epstein-Barr virus nuclear antigen 1 in transgenic mice. Curr Top Microbiol Immunol 182: 375-384.
15. Wilson JB, Weinberg W, Johnson R et al (1990). Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6. Cell 61: 1315-1327.
16. Young LS, Lau R, Rowe M et al (1991). Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia. J Virol 65: 2868-2874.