Glucocorticoids increase fatty-acid synthase mRNA stability in fetal rat lung

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 272, Issue 5 16-5, 1997, Pages

  Xu, Zhi Xin ^a   Rooney, Seamus A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5,6 dichlororibofuranosylbenzimidazole; Fetal lung explants; Lung surfactant; Retinoic acid

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; DEXAMETHASONE; FATTY ACID; FATTY ACID SYNTHASE; GLUCOCORTICOID; LUNG SURFACTANT; MESSENGER RNA; PHOSPHATIDYLCHOLINE; RETINOIC ACID; SURFACTANT;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; FATTY ACID SYNTHESIS; FETUS; FETUS LUNG; FETUS LUNG MATURATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; RNA ANALYSIS; TRANSCRIPTION REGULATION;

EID: 0030965181     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.272.5.l860     Document Type: Article

References (32)

1. Amy, C. M., B. Williams-Ahlf, J. Naggert, and S. Smith. Molecular cloning of the mammalian fatty acid synthase gene and identification of the promoter region. Biochem. J. 271: 675-679, 1990.
2. Amy, C. M., A. Witkowski, J. Naggert, B. Williams, Z. Randhawa, and S. Smith. Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase. Proc. Natl. Acad. Sci. USA 86: 3114-3118, 1989.
3. Beck, K. F., R. Schreglmann, I. Stathopulos, H. Klein, J. Hoch, and M. Schweizer. The fatty acid synthase (FAS) gene and its promoter in Rattus norvegicus. J. DNA Sequence Mapping 2: 359-386, 1992.
4. Bogue, C. W., H. C. Jacobs, D. W. Dynia, C. M. Wilson, and I. Gross. Retinoic acid increases surfactant protein mRNA in fetal rat lung in culture. Am. J. Physiol. 271 (Lung Cell. Mol. Physiol. 15): L862-L868, 1996.
5. Chytil, F. Retinoids in lung development. FASEB J. 10: 986-992, 1996.
6. Deterding, R. R., H. Shimizu, J. H. Fisher, and J. M. Shannon. Regulation of surfactant protein D expression by glucocorticoids in vitro and in vivo. Am. J. Respir. Cell Mol. Biol. 10: 30-37, 1994.
7. Fraslon, C., and J. J. Batenburg. Pre-translational regulation of lipid synthesizing enzymes and surfactant proteins in fetal rat lung in explant culture. FEBS Lett. 325: 285-290, 1993.
8. Fraslon, C., and J. R. Bourbon. Retinoids control surfactant phospholipid biosynthesis in fetal rat lung. Am. J. Physiol. 266 (Lung Cell. Mol. Physiol. 10): L705-L712, 1994.
9. 1 receptor-mediated inhibition of surfactant secretion in rat type II pneumocytes. Am. J. Physiol. 258 (Lung Cell. Mol. Physiol. 2): L45-L51, 1990.
10. Gonzales, L. W., P. L. Ballard, and J. Gonzales. Glucocorticoid and cAMP increase fatty acid synthetase mRNA content in human fetal lung explants. Biochim. Biophys. Acta 1215: 49-58, 1994.
11. Gonzales, L. W., R. Ertsey, P. L. Ballard, D. Froh, J. Goerke, and J. Gonzales. Glucocorticoid stimulation of fatty acid synthesis in explants of human fetal lung. Biochim. Biophys. Acta 1042: 1-12, 1990.
12. Harrold, S., C. Genovese, B. Kobrin, S. L. Morrison, and C. Milcarek. A comparison of apparent mRNA half-life using kinetic labeling techniques vs. decay following administration of transcriptional inhibitors. Anal. Biochem. 198: 19-29, 1991.
13. Hillgartner, F. B., L. M. Salati, and A. G. Goodridge. Physiological and molecular mechanisms involved in nutritional regulation of fatty acid synthesis. Physiol. Rev. 75: 47-76, 1995.
14. Hogan, M., M. Kuliszewski, W. Lee, and M. Post. Regulation of phosphatidylcholine synthesis in maturing type II cells: increased mRNA stability of CTP: phosphocholine cytidylyltransferase. Biochem. J. 314: 799-803, 1996.
15. Joyeux, C., H. Rochefort, and D. Chalbos. Progestin increases gene transcription and mRNA stability of fatty acid synthetase in breast cancer cells. Mol. Endocrinol. 3: 681-686, 1989.
16. Kresch, M. J., and I. Gross. The biochemistry of fetal lung development. Clin. Perinatol. 14: 481-507, 1987.
17. Lu, Z., Y. Gu, and S. A. Rooney. Glucocorticoid regulation of the fatty acid synthase (FAS) gene (Abstract). FASEB J. 11: A558, 1997.
18. Mallampalli, R. K., M. E. Walter, M. W. Peterson, and G. W. Hunninghake. Betamethasone activation of CTP: cholinephosphate cytidylyltransferase in vivo is lipid dependent. Am. J. Respir. Cell Mol. Biol. 10: 48-57, 1994.
19. Metzler, M. D., and J. M. Snyder. Retinoic acid differentially regulates expression of surfactant-associated proteins in human fetal lung. Endocrinology 133: 1990-1998, 1993.
20. Moustaïd, N., and H. S. Sul. Regulation of expression of the fatty acid synthase gene in 3T3-L1 cells by differentiation and triiodothyronine. J. Biol. Chem. 266: 18550-18554, 1991.
21. Pope, T. S., D. A. Smart, and S. A. Rooney. Hormonal effects on fatty-acid synthase in cultured fetal rat lung; induction by dexamethasone and inhibition of activity by triiodothyronine. Biochim. Biophys. Acta 959: 169-177, 1988.
22. Rooney, S. A. The surfactant system and lung phospholipid biochemistry. Am. Rev. Respir. Dis. 131: 439-460, 1985.
23. Rooney, S. A. Fatty acid biosynthesis in developing fetal lung. Am. J. Physiol. 257 (Lung Cell. Mol. Physiol. 1): L195-L201, 1989.
24. Rooney, S. A., D. A. Smart, P. A. Weinhold, and D. A. Feldman. Dexamethasone increases the activity but not the amount of choline-phosphate cytidylyltransferase in fetal rat lung. Biochim. Biophys. Acta 1044: 385-389, 1990.
25. Rooney, S. A., S. L. Young, and C. R. Mendelson. Molecular and cellular processing of lung surfactant. FASEB J. 8: 957-967, 1994.
26. Semenkovich, C. F., T. Coleman, and R. Goforth. Physiologic concentrations of glucose regulate fatty acid synthase activity in HepG2 cells by mediating fatty acid synthase mRNA stability. J. Biol. Chem. 268: 6961-6970, 1993.
27. Smith, S. The animal fatty acid synthase: one gene, one polypeptide, seven enzymes. FASEB J. 8: 1248-1259, 1994.
28. Xu, Z. X., D. A. Smart, and S. A. Rooney. Glucocorticoid induction of fatty-acid synthase mediates the stimulatory effect of the hormone on choline-phosphate cytidylyltransferase activity in fetal rat lung. Biochim. Biophys. Acta 1044: 70-76, 1990.
29. Xu, Z. X., W. Stenzel, S. M. Sasic, D. A. Smart, and S. A. Rooney. Glucocorticoid regulation of fatty acid synthase gene expression in fetal rat lung. Am. J. Physiol. 265 (Lung Cell. Mol. Physiol. 9): L140-L147, 1993.
30. Xu, Z. X., C. J. Viviano, and S. A. Rooney. Glucocorticoid stimulation of fatty-acid synthase gene transcription in fetal rat lung: antagonism by retinoic acid. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L683-L690, 1995.
31. Yamamoto, K. R. Steroid receptor regulated transcription of specific genes and gene networks. Annu. Rev. Genet. 19: 209-252, 1985.
32. Yankulov, K., K. Yamashita, R. Roy, J. M. Egly, and D. L. Bentley. The transcription elongation inhibitor 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole inhibits transcription factor IIH-associated protein kinase. J. Biol. Chem. 270: 23922-23925, 1995.