-
1
-
-
0028806049
-
Current status of endocrine therapy for metastatic breast cancer
-
Kimmick G, Muss HB: Current status of endocrine therapy for metastatic breast cancer Oncology 9:877-890, 1995.
-
(1995)
Oncology
, vol.9
, pp. 877-890
-
-
Kimmick, G.1
Muss, H.B.2
-
2
-
-
0028861586
-
Use of tamoxifen for breast cancer: Twenty-eight years later
-
Jaiyesimi LA, Buzdar AU, Decker DA, et al: Use of tamoxifen for breast cancer: Twenty-eight years later. J Clin Oncol 13:513-529, 1995.
-
(1995)
J Clin Oncol
, vol.13
, pp. 513-529
-
-
Jaiyesimi, L.A.1
Buzdar, A.U.2
Decker, D.A.3
-
3
-
-
0029932612
-
Tamoxifen in postmenopausal women: A safety perspective
-
Robinson E, Kimmick GG, Muss HB: Tamoxifen in postmenopausal women: A safety perspective. Drugs & Aging 8:329-337, 1996.
-
(1996)
Drugs & Aging
, vol.8
, pp. 329-337
-
-
Robinson, E.1
Kimmick, G.G.2
Muss, H.B.3
-
4
-
-
0024506261
-
A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors
-
Fisher B, Costantino J, Redmond C, et al: A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. N Engl J Med 320:479-484, 1989.
-
(1989)
N Engl J Med
, vol.320
, pp. 479-484
-
-
Fisher, B.1
Costantino, J.2
Redmond, C.3
-
5
-
-
0021918182
-
Controlled trial of tamoxifen as single adjuvant agent in management of early breast cancer
-
Nolvadex Adjuvant Trial Organization: Controlled trial of tamoxifen as single adjuvant agent in management of early breast cancer. Lancet 1:836-840, 1985.
-
(1985)
Lancet
, vol.1
, pp. 836-840
-
-
-
6
-
-
0025833585
-
Fatal myocardial infarction in the Scottish adjuvant tamoxifen trial
-
McDonald CC, Stewart HJ, Scottish Breast Cancer Committee: Fatal myocardial infarction in the Scottish adjuvant tamoxifen trial. Br Med J 303:435-437, 1991.
-
(1991)
Br Med J
, vol.303
, pp. 435-437
-
-
McDonald, C.C.1
Stewart, H.J.2
-
7
-
-
0027325734
-
Cardiac and thromboembolic morbidity among postmenopausal women with early stage breast cancer in a randomized trial of adjuvant tamoxifen
-
Rutqvist LE, Mattsson A, Stockholm Breast Cancer Study Group: Cardiac and thromboembolic morbidity among postmenopausal women with early stage breast cancer in a randomized trial of adjuvant tamoxifen. J Natl Cancer Inst 85:1398-1406, 1993.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1398-1406
-
-
Rutqvist, L.E.1
Mattsson, A.2
-
8
-
-
0028129023
-
The Royal Marsden Hospital pilot tamoxifen chemoprevention trial
-
Powles TJ, Jones AL, Ashley SE, et al: The Royal Marsden Hospital pilot tamoxifen chemoprevention trial. Breast Cancer Res Treat 31:73-83, 1994.
-
(1994)
Breast Cancer Res Treat
, vol.31
, pp. 73-83
-
-
Powles, T.J.1
Jones, A.L.2
Ashley, S.E.3
-
11
-
-
0028208456
-
Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14
-
Fisher B, Costantino JP, Redmond CK, et al: Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14. J Natl Cancer Inst 86:527-537, 1994.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 527-537
-
-
Fisher, B.1
Costantino, J.P.2
Redmond, C.K.3
-
12
-
-
0025009192
-
Chemical carcinogenesis: Too many rodent carcinogens?
-
Ames BN, Gold LS: Chemical carcinogenesis: too many rodent carcinogens? Proc Natl Acad Sci 87:7772-7776, 1990.
-
(1990)
Proc Natl Acad Sci
, vol.87
, pp. 7772-7776
-
-
Ames, B.N.1
Gold, L.S.2
-
13
-
-
0030066508
-
A study of the structural basis of the carcinogenicity of tamoxifen, toremifene and their metabolites
-
Cunningham A, Klopman G, Rosenkranz HS: A study of the structural basis of the carcinogenicity of tamoxifen, toremifene and their metabolites. Mutation Res 349:85-94, 1996.
-
(1996)
Mutation Res
, vol.349
, pp. 85-94
-
-
Cunningham, A.1
Klopman, G.2
Rosenkranz, H.S.3
-
14
-
-
0030050137
-
Identification of the major tamoxifen-deoxyguanosme adduct formed in liver DNA of rats treated with tamoxifen
-
Osborne MR, Hewer A, Hardcastle IR, et al: Identification of the major tamoxifen-deoxyguanosme adduct formed in liver DNA of rats treated with tamoxifen. Cancer Res 56:66-71, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 66-71
-
-
Osborne, M.R.1
Hewer, A.2
Hardcastle, I.R.3
-
15
-
-
0028172242
-
α-hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA binding activity in rat hepatocytes
-
Phillips DH, Carmichael PL, Hewer A, et al: α-hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA binding activity in rat hepatocytes Cancer Res 54:5518-5522, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 5518-5522
-
-
Phillips, D.H.1
Carmichael, P.L.2
Hewer, A.3
-
16
-
-
0030069966
-
Tamoxifen metabolic activation: Comparison of DNA adducts formed by microsomal activation and chemical activation of tamoxifen and 4-hydroxytamoxifen with DNA adducts formed in vivo
-
Moorthy B, Sriram P, Pathak DN, et al: Tamoxifen metabolic activation: comparison of DNA adducts formed by microsomal activation and chemical activation of tamoxifen and 4-hydroxytamoxifen with DNA adducts formed in vivo. Cancer Res 56:53-57, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 53-57
-
-
Moorthy, B.1
Sriram, P.2
Pathak, D.N.3
-
17
-
-
0028326053
-
A mechanistic hypothesis for DNA adduct formation by tamoxifen following hepatic metabolism
-
Potter GA, McCague R, Jarman M, et al: A mechanistic hypothesis for DNA adduct formation by tamoxifen following hepatic metabolism. Carcinogenesis 15:439-442, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 439-442
-
-
Potter, G.A.1
McCague, R.2
Jarman, M.3
-
18
-
-
0028172454
-
32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA formation and identification of 4-hydroxytamoxifen as a proximate metabolite
-
32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA formation and identification of 4-hydroxytamoxifen as a proximate metabolite. Carcinogenesis 15:2087-2094, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2087-2094
-
-
Randerath, K.1
Moorthy, B.2
Mabon, N.3
-
19
-
-
0028210878
-
DNA adduct formation by tamoxifen with rat and human liver microsomal activating systems
-
Pathak DN, Bodell WJ: DNA adduct formation by tamoxifen with rat and human liver microsomal activating systems. Carcinogenesis 15:529-532, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 529-532
-
-
Pathak, D.N.1
Bodell, W.J.2
-
20
-
-
0026606580
-
Induction of covalent DNA adducts in rodents by tamoxifen
-
Han X, Liehr JG: Induction of covalent DNA adducts in rodents by tamoxifen. Cancer Res 52:1360-1363, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 1360-1363
-
-
Han, X.1
Liehr, J.G.2
-
21
-
-
0028038046
-
The incidence of hepatocellular carcinomain US white women with breast cancer after the introduction of tamoxifen in 1977
-
Mühlemann K, Cook LS, Weiss NS: The incidence of hepatocellular carcinomain US white women with breast cancer after the introduction of tamoxifen in 1977. Breast Cancer Res Treat 30:201-204, 1994.
-
(1994)
Breast Cancer Res Treat
, vol.30
, pp. 201-204
-
-
Mühlemann, K.1
Cook, L.S.2
Weiss, N.S.3
-
23
-
-
0003121713
-
Relationships between carcinogen exposure, DNA adducts and Carcinogenesis
-
Clayson DB, Munro IC, Shubik P et al (eds): Elsevier Science Publishers
-
Swenberg JA, Fedtke N, Fennell TR: Relationships between carcinogen exposure, DNA adducts and Carcinogenesis, in Clayson DB, Munro IC, Shubik P et al (eds): Progress in Predictive Toxicology, pp 161-184, Elsevier Science Publishers, 1990.
-
(1990)
Progress in Predictive Toxicology
, pp. 161-184
-
-
Swenberg, J.A.1
Fedtke, N.2
Fennell, T.R.3
-
24
-
-
0030250912
-
DNA adducts: Biological markers of exposure and potential applications to risk assessment
-
La DK, Swenberg JA: DNA adducts: Biological markers of exposure and potential applications to risk assessment. Mutat Res 365:129-146, 1996.
-
(1996)
Mutat Res
, vol.365
, pp. 129-146
-
-
La, D.K.1
Swenberg, J.A.2
-
25
-
-
0029985407
-
Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: Comparisons between human, rat and mouse hepatocytes
-
Phillips DH, Carmichael PL, Hewer A, et al: Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: Comparisons between human, rat and mouse hepatocytes. Carcinogenesis 17:89-94, 1996
-
(1996)
Carcinogenesis
, vol.17
, pp. 89-94
-
-
Phillips, D.H.1
Carmichael, P.L.2
Hewer, A.3
-
26
-
-
0027221052
-
Metabolism of the antimammary cancer antiestrogenic agent tamoxifen: Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation
-
Mani C, Gelboin HV, Park SS, et al: Metabolism of the antimammary cancer antiestrogenic agent tamoxifen: Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation. Drug Metab Dispos 21:645-656, 1993.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 645-656
-
-
Mani, C.1
Gelboin, H.V.2
Park, S.S.3
-
27
-
-
0028177045
-
A comparative study of tamoxifen metabolism in the female rat, mouse and human liver microsomes
-
Lim CK, Yuan Z-X, Lamb JH, et al: A comparative study of tamoxifen metabolism in the female rat, mouse and human liver microsomes. Carcinogenesis 15-5898-5893, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 5898-15893
-
-
Lim, C.K.1
Yuan, Z.-X.2
Lamb, J.H.3
-
28
-
-
0028979270
-
32P-postlabelled DNA adducts in liver obtained from women treated with tamoxifen
-
32P-postlabelled DNA adducts in liver obtained from women treated with tamoxifen. Carcinogenesis 16:1651-1654, 1995.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1651-1654
-
-
Martin, E.A.1
Rich, K.J.2
White, I.N.H.3
-
29
-
-
0029903222
-
Tamoxifen does not form detectable DNA adducts in white blood cells of breast cancer patients
-
Phillips DH, Hewer A, Grover PL, et al: Tamoxifen does not form detectable DNA adducts in white blood cells of breast cancer patients. Carcinogenesis 17:1149-1152, 1996.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1149-1152
-
-
Phillips, D.H.1
Hewer, A.2
Grover, P.L.3
-
30
-
-
0029978834
-
Lack of genotoxicity of tamoxifen in human endometrium
-
Carmichael PL, Ugwumadu AHN, Neven P: Lack of genotoxicity of tamoxifen in human endometrium Cancer Res 56:1475-1479, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 1475-1479
-
-
Carmichael, P.L.1
Ugwumadu, A.H.N.2
Neven, P.3
-
31
-
-
0028979277
-
DNA adducts caused by tamoxifen and toremifene in human microsomal system and lymphocytes in vitro
-
Hemminki K, Widlak P, Hou S-M: DNA adducts caused by tamoxifen and toremifene in human microsomal system and lymphocytes in vitro. Carcinogenesis 16:1661-1664, 1995.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1661-1664
-
-
Hemminki, K.1
Widlak, P.2
Hou, S.-M.3
-
32
-
-
0029815539
-
Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: Comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen
-
Pathak DN, Pongracz K, Bodell WJ: Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: Comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen. Carcinogenesis 17:1785-1790, 1996.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1785-1790
-
-
Pathak, D.N.1
Pongracz, K.2
Bodell, W.J.3
-
33
-
-
0027054733
-
Genotoxic potential of tamoxifen and analogues in female Fischer F344/N rats, DBA/2 and C57B1/6 mice and in human MCL-5 cells
-
White INH, de Matteis F, Davies A, et al: Genotoxic potential of tamoxifen and analogues in female Fischer F344/N rats, DBA/2 and C57B1/6 mice and in human MCL-5 cells. Carcinogenesis 13:2197-2203, 1992.
-
(1992)
Carcinogenesis
, vol.13
, pp. 2197-2203
-
-
White, I.N.H.1
De Matteis, F.2
Davies, A.3
-
34
-
-
0029052183
-
32P-postlabeling in three rat strains exposed to dietary tamoxifen: The relationship between cell proliferation and liver tumor formation
-
32P-postlabeling in three rat strains exposed to dietary tamoxifen: The relationship between cell proliferation and liver tumor formation. Carcinogenesis 16:1299-1304, 1995.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1299-1304
-
-
Carthew, P.1
Rich, K.J.2
Martin, E.A.3
-
35
-
-
0029745072
-
Tamoxifen-induced DNA adducts in endometrial samples from breast cancer patients
-
Hemminki K, Rajaniemi H, Lindahl B, et al: Tamoxifen-induced DNA adducts in endometrial samples from breast cancer patients. Cancer Res 56:4374-4377, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 4374-4377
-
-
Hemminki, K.1
Rajaniemi, H.2
Lindahl, B.3
-
36
-
-
0027397629
-
Tamoxifen induces hepatocellular carcinoma in rat liver: A 1-year study with two antiestrogens
-
Hirsimaki P, Hirsimaki Y, Nieminen L, et al: Tamoxifen induces hepatocellular carcinoma in rat liver: A 1-year study with two antiestrogens. Arch Toxicol 67:49-54, 1993.
-
(1993)
Arch Toxicol
, vol.67
, pp. 49-54
-
-
Hirsimaki, P.1
Hirsimaki, Y.2
Nieminen, L.3
-
37
-
-
0027308685
-
The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat
-
Williams GM, Iatropoulos MJ, Djordjevic MV, et al: The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat. Carcinogenesis 14:3l5-317, 1993.
-
(1993)
Carcinogenesis
, vol.14
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Djordjevic, M.V.3
-
38
-
-
0027201501
-
Two-year carcinogenicity study of tamoxifen in Alderly Park Wistar-derived rats
-
Greaves P, Goonelilleke R, Nunn G, et al: Two-year carcinogenicity study of tamoxifen in Alderly Park Wistar-derived rats. Cancer Res 53:3919-3924, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 3919-3924
-
-
Greaves, P.1
Goonelilleke, R.2
Nunn, G.3
-
39
-
-
0000151348
-
Tamoxifen
-
Lawrence DR, McLean AEM, Weatherall M (eds): Orlando FL, Academic Press
-
Tucker MJ, Adam HK, Patterson JS: Tamoxifen, in Lawrence DR, McLean AEM, Weatherall M (eds): Safety Testing of New Drugs, pp 125-161, Orlando FL, Academic Press, 1984.
-
(1984)
Safety Testing of New Drugs
, pp. 125-161
-
-
Tucker, M.J.1
Adam, H.K.2
Patterson, J.S.3
-
40
-
-
0023841540
-
Tamoxifen inhibits estrogen-induced hepatic injury in hamsters
-
Coe JE, Ross MJ: Tamoxifen inhibits estrogen-induced hepatic injury in hamsters. Endocrinology 122:137-144, 1988.
-
(1988)
Endocrinology
, vol.122
, pp. 137-144
-
-
Coe, J.E.1
Ross, M.J.2
-
41
-
-
0026565963
-
Tamoxifen prevents induction of hepatic neoplasms by zeranol, an estrogenic food contaminant
-
Coe JE, Ishak KG, Ward JM, et al: Tamoxifen prevents induction of hepatic neoplasms by zeranol, an estrogenic food contaminant Proc Natl Acad Sci USA 89:1085-1089, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1085-1089
-
-
Coe, J.E.1
Ishak, K.G.2
Ward, J.M.3
-
42
-
-
0028810502
-
Comparison of the effects of tamoxifen and toremifene on liver and kidney tumor promotion in female rats
-
Dragan YP, Vaughan J, Jordan VC, Pitot HC: Comparison of the effects of tamoxifen and toremifene on liver and kidney tumor promotion in female rats. Carcinogenesis 16:2733-2741, 1995.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2733-2741
-
-
Dragan, Y.P.1
Vaughan, J.2
Jordan, V.C.3
Pitot, H.C.4
-
43
-
-
0029857622
-
Toxicological significance of DNA adducts: Summary of discussions with an expert panel
-
Nestmann ER, Bryant DW, Carr CJ: Toxicological significance of DNA adducts: Summary of discussions with an expert panel. Regul Toxicol Pharmacol 24:9-18, 1996.
-
(1996)
Regul Toxicol Pharmacol
, vol.24
, pp. 9-18
-
-
Nestmann, E.R.1
Bryant, D.W.2
Carr, C.J.3
|