Electrophysiological effects of EGIS-7229, a new antiarrhythmic agent, in isolated mammalian and human cardiac tissues

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 355, Issue 3, 1997, Pages 398-405

  Pankucsi, Csaba ^a   Bányász, Tamás ^a   Magyar, János ^a   Gyönös, Ildikó ^b   Kovács, Anikó ^b   Varró, András ^c   Szénási, Gábor ^b   Nánási, Péter P ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b EGIS PHARMACEUTICALS LTD   (Hungary)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Action potential duration; Antiarrhythmic drugs; Cardiac muscle; Electrophysiology Recovery of V(max); Frequency dependence; Potassium channels; Sodium channels

Indexed keywords

5 CHLORO 4 [3 [2 (3,4 DIMETHOXYPHENYL)ETHYLAMINO]PROPYLAMINO] 3(2H) PYRIDAZINONE FUMARATE; 5 CHLORO 4 [3 [N [2 (3,4 DIMETHOXYPHENYL)ETHYL] N METHYLAMINO]PROPYLAMINO] 3(2H) PYRIDAZINONE; ANTIARRHYTHMIC AGENT; NICORANDIL; NIFEDIPINE; POTASSIUM CHANNEL; SOTALOL; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; ELECTROPHYSIOLOGY; GUINEA PIG; HEART MUSCLE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MEMBRANE STEADY POTENTIAL; NONHUMAN; PURKINJE FIBER; RABBIT; SPECIES DIFFERENCE;

EID: 0030964399     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00004960     Document Type: Article

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