Evaluation of agonal artifacts in the myocardium using a combination of histological stains and immunohistochemistry

American Journal of Forensic Medicine and Pathology

Volumn 18, Issue 2, 1997, Pages 163-167

  Edston, Erik ^a,b,c  

^a LINKÖPING UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

histological technique; immunohistochemistry; myocardial infarction; sudden death

Indexed keywords

COMPLEMENT MEMBRANE ATTACK COMPLEX; DYE; EOSIN; FAST BLUE; FUCHSINE; HEMATOXYLIN; MYOGLOBIN; PHOSPHOTUNGSTIC ACID; PICRIC ACID; POLYCLONAL ANTIBODY;

ADULT; ARTICLE; ARTIFACT; AUTOPSY; CARBON MONOXIDE INTOXICATION; CONTROLLED STUDY; CORONARY ARTERY THROMBOSIS; FEMALE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; STAINING; SUDDEN DEATH; SUICIDE;

ADULT; ANTIBODIES; ARTIFACTS; DEATH, SUDDEN, CARDIAC; DIAGNOSIS, DIFFERENTIAL; FEMALE; FORENSIC MEDICINE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIUM; STAINING AND LABELING;

EID: 0030963136     PISSN: 01957910     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000433-199706000-00011     Document Type: Article

References (15)

1. Nachlas MM, Shnitka TK. Macroscopic identification of early myocardial infarcts by alterations in dehydrogenase activity. Am J Pathol 1963;42:379-404.
2. Zugibe FT, Bell P, Conley TL, Standish ML. Determination of cardiac alterations at autopsy in the absence of gross microscopical changes. Arch Pathol 1966;81:409-11.
3. Lie JT, Holley KE, Kampa WR, Titus JL. New histochemical method for morphologic diagnosis of early stages of myocardial ischemia. Mayo Clin Proc 1971;46:319-27.
4. Arnold G, Kaiser C, Fischer R. Myofibrillar degeneration - a common type of myocardial lesion and its selective identification by a modified luxol fast blue stain. Pathol Res Pract 1985;180:405-15.
5. Leadbetter S, Wawman HM, Jasani B. Further evaluation of immunocytochemical staining in the diagnosis of early myocardial ischaemic/hypoxic damage. Forensic Sci Int 1990;45:135-41.
6. Schäfer H, Mathey D, Hugo F, Bhakdi S. Deposition of the terminal complement complex in infarcted areas of human myocardium. J Immunol 1986;137:1945-9.
7. Thomsen H, Held H. Immunohistochemical detection of C5b-9(m) in myocardium: an aid in distinguishing ischemic heart muscle necrosis from other forms of lethal myocardial injury. Forensic Sci Int 1995;71:87-95.
8. Brinkmann B, Sepulchre MA, Fechner G. The application of selected histochemical and immunohistochemical markers and procedures to the diagnosis of early myocardial damage. Int J Legal Med 1993;106:135-41.
9. Edston E, Kawa K. Immunohistochemical detection of early myocardial infarction. An evaluation of antibodies against the terminal complement complex (C5b-9). Int J Legal Med 1995;108:27-30.
10. Kloner RA, Ganote CE, Whalen DA Jr, Jennings RB. Effect of a transient period of ischemia on myocardial cells. 2. Fine structure during the first few minutes of reflow. Am J Pathol 1974;74:399-422.
11. Ikeda N, Harada A, Suzuki T. The course of respiration and circulation in death due to typical hanging. Int J Legal Med 1992;104:313-15.
12. Flanagan NG, Wootton DG, Smith G, Goff DK. An unusual case of carbon monoxide poisoning. Med Sci Law 1978;18:117-19.
13. Matsuda M, Fujiwara H, Onodera T, et al. Quantitative analysis of infarct size, contraction band necrosis, and coagulation necrosis in human autopsied hearts with acute myocardial infarction after treatment with selective intracoronary thrombolysis. Circulation 1987;76:981-9.
14. Karch SB, Billingham ME. Morphologic effects of defibrillation: a preliminary report. Crit Care Med 1984;12: 920-1.
15. Reichenbach DD, Benditt EP. Catecholamines and cardiomyopathy: the pathogenesis and potential importance of myofibrillar degeneration. Hum Pathol 1970; 1:125-50.