Sterically crowded cyclohexanes - 10. Synthesis, conformation and dynamics of 8,8,13,13-tetramethyltetraspiro[2.0.3.1.3.1.3.0]heptadecane

Tetrahedron

Volumn 53, Issue 22, 1997, Pages 7529-7538

  Rissom, Beate ^a   Fitjer, Lutz ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXANE DERIVATIVE; POLYCYCLIC HYDROCARBON;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030963047     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(97)00440-7     Document Type: Article

References (24)

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6. Fitjer, L. Justus, K.; Puder, P.; Dittmer, M.; Haßler, C.; Noltemeyer, M. Angew. Chem. 1991, 103, 431-433; Angew. Chem. Int. Ed. Engl. 1991, 30, 436-438.
7. Fitjer, L.; Klages, U.; Kühn, W.; Stephenson, D. S.; Binsch, G.; Noltemeyer, M.; Egert, E.; Sheldrick, G. M. Tetrahedron 1984, 40, 4337-4349.
8. (a) Fitjer, L.; Scheuermann, H.-J.; Klages, U. Wehle, D.; Stephenson, D. S.; Binsch, G. Chem. Ber. 1986, 119, 1144-1161.
9. (b) Traetteberg, M.; Bakken, P.; Fitjer, L.; Scheuermann, H.-J. J. Mol. Struct. 1987, 159, 325-334.
10. We use the term "conformational isomerism" in a sense defined by Dale (Dale, J. Stereochemie und Konformationsanalyse; Verlag Chemie: Weinheim, 1978). For this and other definitions, see also: Ernst, L. Chem. Unserer Zeit 1983, 17, 21-30.
11. We use the term "conformational isomerism" in a sense defined by Dale (Dale, J. Stereochemie und Konformationsanalyse; Verlag Chemie: Weinheim, 1978). For this and other definitions, see also: Ernst, L. Chem. Unserer Zeit 1983, 17, 21-30.
12. For another case of conformational isomerism, see: Wehle, D.; Fitjer, L. Tetrahedron Lett. 1986, 27, 5843-5846.
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19. With thionyl chloride in pyridine complete rearrangement to bicyclononene 20 occurred.
20. In a similar case (ref 5), a preferential equatorial attack of a carbenoid has been proven.
21. Binsch, G.; Kessler, H. Angew. Chem. 1980, 92, 445-463; Angew. Chem. Int. Ed. Engl. 1980, 19, 411-428.
22. Binsch, G.; Kessler, H. Angew. Chem. 1980, 92, 445-463; Angew. Chem. Int. Ed. Engl. 1980, 19, 411-428.
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