Characterization of metabotropic glutamate receptors in rat C6 glioma cells

European Journal of Pharmacology

Volumn 326, Issue 1, 1997, Pages 85-91

  Albasanz, José Luis ^a   Ros, Manuel ^a   Martín, Mairena ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

C6 glioma cell; G protein; Metabotropic glutamate receptor; trans ACPD

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 (CARBOXYCYCLOPROPYL)GLYCINE; GLUTAMIC ACID; GUANYLYLIMIDODIPHOSPHATE; IBOTENIC ACID; METABOTROPIC RECEPTOR; QUISQUALIC ACID;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; GLIOMA CELL; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN NEOPLASMS; CELL MEMBRANE; CYCLOLEUCINE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLIOMA; GLUTAMIC ACID; GUANYLYL IMIDODIPHOSPHATE; KINETICS; NEUROPROTECTIVE AGENTS; RADIOLIGAND ASSAY; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; TUMOR CELLS, CULTURED;

EID: 0030962938     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)00154-4     Document Type: Article

References (54)

1. 2+ signal transduction. J. Biol. Chem. 267, 13361-13368.
2. Aramori, I., Nakanishi, S., 1992. Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR1, in transfected CHO cells. Neuron 8, 757-765.
3. Birnbaumer, L., 1990. G-protein in signal transduction. Annu. Rev. Pharmacol. Toxicol. 30, 675-705.
4. Bliss, T.V., Collingridge, G.L., 1993. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
5. Boss, V., Conn, P.J., 1992. Metabotropic excitatory amino acid receptor activation stimulates phospholipase D in hippocampal slices. J. Neurochem. 59, 2340-2343.
6. Catania, M.V., De Socarraz, H., Penney, J.B., Young, A.B., 1994. Metabotropic glutamate receptor heterogeneity in rat brain. Mol. Pharmacol. 45, 626-636.
7. 3H]Glutamate labels the metabotropic excitatory amino acid receptor in rodent brain. Neurosci. Lett. 113, 78-83.
8. Collingridge, G.L., Singer, W., 1990. Excitatory amino acid receptors and synaptic plasticity. Trends Pharmacol. Sci. 11, 290-296.
9. Desai, M., Conn, P.J., 1990. Selective activation of phosphoinositide hydrolysis by a rapid analogue of glutamate. Neurosci. Lett. 109, 157-162.
10. Dumuis, A., Pin, J.P., Oomagari, K., Sebben, M., Bockaert, J., 1990. Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic glutamate quisqualate receptors. Nature 347, 182-184.
11. Duvoisin, R.M., Zhang, C., Ramonell, K., 1995. A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J. Neurosci. 15, 3075-3083.
12. Fonnum, F., 1984. Glutamate: a neurotransmitter in mammalian brain. J. Neurochem. 42, 1-7.
13. Gilman, A.G., 1987. G-proteins: transducers of receptor generated signals. Annu. Rev. Biochem. 56, 615-649.
14. Green, R.D., 1984. Reciprocal modulation of agonist and antagonist binding to inhibitory adenosine receptors by 5′-guanylylimi-dodiphosphate and monovalent cations. J. Neurochem. 4, 2472-2476.
15. Hayashi, Y., Momiyama, A., Takahashi, T., Ohishi, H., Ogawa-Meguro, R., Shigemoto, R., Mizuno, N., Nakanishi, S., 1993. Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb. Nature 366, 687-690.
16. Hollmann, M., Heinemann, S., 1994. Cloned glutamate receptors. Annu. Rev. Neurosci. 17, 31-108.
17. Houamed, K.M., Kuijper, J.L., Gilbert, T.L., Haldeman, B.A., O'Hara, P.J., Mulvihill, E.R., Almers, W., Hagen, F.S., 1991. Cloning, expression and gene structure of a G-protein-coupled glutamate receptor from rat brain. Science 252, 1318-1321.
18. Iversen, L., Mulvihill, E., Haldeman, B., Diemer, N.H., Kaiser, F., Sheardown, M., Kristensen, P., 1994. Changes in metabotropic glutamate receptor mRNA levels following global ischemia: increase of a putative presynaptic subtype (mGluR4) in highly vulnerable rat brain areas. J. Neurochem. 63, 625-633.
19. Izumi, Y., Clifford, D.B., Zorumski, C.F., 1991. 2-Amino-3-phosphono-propionate block the induction and maintenance of long term potentiation in rat hippocampal slices. Neurosci. Lett. 122, 187-190.
20. Kessler, M., Terramani, T., Lynch, G., Baudry, M., 1989. A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonist. J. Neurochem. 52, 1319-1328.
21. Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
22. Manzoni, O., Fagni, L., Pin, J.P., Rassendren, F., Poulat, F., Sladeczek, F., Bockaert, J., 1990. (trans)-1-Amino-cyclopentyl-1,3-dicarboxylate stimulates quisqualate phosphoinositide-coupled receptors but not ionotropic glutamate receptors in striatal neurons and Xenopus oocytes. Mol. Pharmacol. 38, 1-6.
23. Manzoni, O., Prezeau, L., Sladeczek, F., Bockaert, J., 1992. trans-ACPD inhibits cAMP formation via a pertussis toxin-sensitive G-protein. Eur. J. Pharmacology Mol. Pharmacol. Sect. 225, 357-358.
24. 3H]glutamate binding sites in bovine brain coated vesicles. Eur. J. Pharmacol. 207, 215-224.
25. Martín, M., Sanz, J.M., Cubero, A., 1993. Characterization of a metabotropic glutamate receptors coupled to a pertussis toxin sensitive G-protein in bovine brain coated vesicles. FEBS Lett. 316, 191-196.
26. Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., Nakanishi, S., 1991. Sequence and expression of a metabotropic glutamate receptor. Nature 349, 760-765.
27. Meldrum, B., Garthwaite, J., 1990. Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sci. 11, 379-387.
28. Milligan, G., 1993. Mechanisms of multifunctional signaling by G-protein linked receptors. Trends Pharmacol. Sci. 14, 239-244.
29. Minakami, R., Katsuki, F., Yamamoto, T., Nakamura, K., Sugiyama, H., 1994. Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5. Biochem. Biophys. Res. Commun. 199, 1136-1143.
30. Monaghan, D.T., Bridges, R.J., Cotman, C.W., 1989. The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu. Rev. Pharmacol. Toxicol. 29, 365-402.
31. Nakajima, Y., Iwakabe, H., Akazawa, C., Nawa, H., Shigemoto, R., Mizuno, N., Nakanishi, S., 1993. Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR4 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. Biol. Chem. 268, 11868-11873.
32. Nakanishi, S., 1992. Molecular diversity of glutamate receptors and implications for brain function. Science 258, 597-603.
33. Nakanishi, S., 1994. Metabotropic glutamate receptors: synaptic transmission, modulation and plasticity. Neuron 13, 1031-1037.
34. Nakanishi, S., Masu, M., 1994. Molecular diversity and functions of glutamate receptors. Annu. Rev. Biophys. Biomol. Struct. 23, 319-348.
35. Nicoletti, F., Wroblewski, J.T., Fadda, E., Costa, E., 1988. Pertussis toxin inhibits signal transduction at a specific metabotropic glutamate receptor in primary cultures of cerebellar granule cells. Neuropharmacology 27, 551-556.
36. Okamoto, N., Hori, S., Akazawa, C., Hayashi, Y., Shigemoto, R., Mizuno, N., Nakanishi, S., 1994. Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J. Biol. Chem. 269, 1231-1236.
37. Palmer, E., Monaghan, D.T., Cotman, C.W., 1989. trans-ACPD, a selective agonist of phosphoinositide-coupled excitatory aminoacid receptor. Eur. J. Pharmacol. 166, 585-587.
38. Pang, J., Lo, Y.H., Chandlee, J.M., Rhoads, D.E., 1994. A subtype of the metabotropic glutamate receptor family in the olfactory system of Atlantic salmon. FEBS Lett. 354, 301-304.
39. Pin, J.P., Duvoisin, R., 1995. The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34, 1-26.
40. Pin, J.P., Waeber, C., Prezeu, L., Bockaert, J., Heinemann, S.F., 1992. Alternative splicing generates metabotropic glutamate receptors, inducing different patterns of calcium release in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 89, 10331-10335.
41. Saugstad, J.A., Kinzie, J.M., Mulvihill, E.R., Segerson, T.P., Westbrook, G.L., 1994. Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors. Mol. Pharmacol. 45, 367-372.
42. Sayer, R.J., Schwindt, P.C., Grill, W.E., 1992. Metabotropic glutamate receptor-mediated suppression of L-type calcium current in acutely isolated neocortical neurons. J. Neurophysiol. 68, 833-842.
43. Schoepp, D.D., 1994. Novel functions for subtypes of metabotropic glutamate receptors. Neurochem. Int. 24, 439-449.
44. Schoepp, D.D., Conn, P.J., 1993. Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol. Sci. 14, 13-20.
45. Schoepp, D.D., Bockaert, J., Sladeczek, F., 1990. Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors. Trends Pharmacol. Sci. 11, 508-515.
46. Schoepp, D.D., Johnson, B.G., Monn, J.A., 1992. Inhibition of cyclic AMP formation by a selective metabotropic glutamate receptor agonist. J. Neurochem. 58, 1184-1186.
47. Sladeczek, F., Pin, J.P., Recasens, M., Bockaert, J., Weiss, S., 1985. Glutamate stimulates inositol phosphate formation in striatal neurones. Nature 317, 717-719.
48. Sugiyama, H., Ito, I., Hirono, C., 1987. A new type of glutamate receptor linked to inositol phospholipid metabolism. Nature 325, 531-533.
49. Sugiyama, H., Ito, I., Watanabe, M., 1989. Glutamate receptor subtypes may be classified into two major categories: a study on Xenopus oocytes injected with rat brain mRNA. Neuron 3, 129-132.
50. Tanabe, Y., Masu, M., Ishii, T., Shigemoto, R., Nakanishi, S., 1992. A family of metabotropic glutamate receptors. Neuron 8, 169-179.
51. Tanabe, Y., Nomura, A., Masu, M., Shigemoto, R., Mizuno, N., Nakanishi, S., 1993. Signal transduction, pharmacological properties and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4. J. Neurosci. 13, 1372-1378.
52. Thomsen, C., Mulvihill, E.R., Haldeman, B., Pickering, D.S., Hampson, D.R., Suzdak, P.D., 1993. A pharmacological characterization of the mGluRl alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line. Brain Res. 619, 22-28.
53. Winder, D.G., Conn, P.J., 1992. Activation of metabotropic glutamate receptors in the hippocampus increases cAMP accumulation. J. Neurochem. 59, 375-378.
54. Winder, D.G., Conn, P.J., 1993. Activation of metabotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine. J. Neurosci. 13, 38-44.