A role for the hinge/ear domain of the β chains in the incorporation of AP complexes into clathrin-coated pits and coated vesicles

Cellular and Molecular Life Sciences

Volumn 53, Issue 7, 1997, Pages 611-619

  Clairmont, K B ^a,b   Boll, W ^a   Ericsson, M ^a   Kirchhausen, T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BAYER CORPORATION   (United States)

Author keywords

Adaptors; Coat assembly; Coated pits; Endocytosis; Vesicles

Indexed keywords

CLATHRIN; MEMBRANE PROTEIN; PROTEIN;

ANIMAL CELL; ARTICLE; BETA CHAIN; CHO CELL; COATED VESICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOCYTOSIS; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BLOTTING, WESTERN; CELL MEMBRANE; CHO CELLS; CLATHRIN; COATED PITS, CELL-MEMBRANE; COATED VESICLES; CRICETINAE; DNA, COMPLEMENTARY; ENDOCYTOSIS; EPITOPES; GOLGI APPARATUS; MICROSCOPY, IMMUNOELECTRON; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; RATS; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 0030962786     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000180050080     Document Type: Article

References (40)

1. Virshup D. M. and Bennett V. (1988) Clathrin-coated vesicle assembly polypeptides: physical properties and reconstitution studies with brain membranes. J. Cell Biol. 106: 39-50
2. Matsui W. and Kirchhausen T. (1990) Stabilization of clathrin coats by the core of the clathrin-associated protein complex AP-2, Biochemistry 29: 10791-10798
3. Heuser J. and Kirchhausen T. (1985) Deep-etch views of cluthrin assemblies. J. Ultrastruct. Res. 92: 1-27
4. Vigers G. P., Crowther, R. A. and Pearse B. M. (1986) Location of the 100 kd 50 kd accessory proteins in clathrin coals. EMBO J. 5: 2079-2085
5. Robinson M. S. (1992) Adaptins. Trends Cell Biol. 2: 293-297
6. Zaremba S. and Keen J. H. (1983) Assembly polypeptides from coated vesicles mediate reassembly of unique clathrin coats. J. Cell Biol. 97: 1339-1347
7. Pearse B. M. and Robinson M. S. (1984) Purification and properties of 100-kd proteins from coated vesicles and their reconstitution with clathrin. EMBO J. 3: 1951-1957
8. Smythe E., Carter L. L. and Schmid S. L. (1992) Cytosol- and clathrin-dependent stimulation of endocytosis in vitro by purified adaptors. J. Cell Biol. 119: 1163-1171
9. Pearse B. M. F. (1988) Receptors compete for adaptors found in plasma membrane coated pits. EMBO J. 7: 3331-3336
10. Glickman J. N., Conibear E. and Pearse B. M. (1989) Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor. EMBO J. 8: 1041-1047
11. Sosa M. A., Schmidt B., von Figura K. and Hille-Rehfeld A. (1993) In vitro binding of plasma membrane-coated vesicle adaptors to the cytoplasmic domain of lysosomal acid phosphatase. J. Biol. Chem. 268: 12537-12543
12. Nesterov A., Kurten R. C. and Gill G. N. (1995) Association of Epidermal Growth Factor Receptors with coated pit adaptins via a tyrosine-phosphorylation-regulated mechanism. J. Biol. Chem. 270: 1-8
13. Boll W., Gallusser A. and Kirchhausen T. (1995) Role of the regulatory domain of the EGF-receptor cytoplasmic tail in selective binding of the clathrin-associated complex AP-2. Current Biology 5: 1168-1178
14. Sorkin A. and Carpenter A. (1993) Interaction of activated EGF receptors with coaled pit adaplins. Science 261: 612-615
15. Nesterov A., Wiley H. S. and Gill G. N. (1995) Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins. Proc. Natl Acad. Sci. USA 92: 8719-8723
16. Sorkin A., McKinsey T., Shih W., Kirchhausen T. and Carpenter G. (1995) Stoichiometric interaction of the epidermal growth factor receptor with the clathrin-associated protein complex AP-2. J. Biol. Chem. 270: 619-625
17. Gilboa L., Ben-Levy R., Yarden Y. and Henis Y. I. (1995) Roles for a cytoplasmic tyrosine and tyrosine kinase activity in the interactions of Neu receptors with coated pits. J. Biol. Chem. 270: 7061-7067
18. Ohno H., Stewart J., Fournier M. C., Bosshart H., Rhee I., Miyatake S. et al. (1995) Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science 269: 1872-1875
19. Boll W., Ohno H., Songyang Z., Rapoport I., Cantley L. C., Bonifacino J. S. et al. (1996) Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes. EMBO J. 15: 5789-5795
20. Rapoport I., Miyazaki M., Boll W., Duckworth B., Cantley L. C., Shoelson S. et al. (1997) Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes. EMBO J. 16: 2240-2250
21. Kirchhausen T. (1993) Coated pits and coated vesicles -sorting it all out. Curr. Opin. Struct. Biol. 3: 182-188
22. Heuser J. E. and Keen J. (1988) Deep-etch visualization of proteins involved in clathrin assembly. J. Cell Biol. 107: 877-886
23. Kirchhausen T., Nathanson K. L., Matsui W., Vaisberg A., Chow E. P., Burne C. el al. (1989) Structural and functional division into two domains of the large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2. Proc. Natl Acad. Sci. USA 86: 2612-2616
24. Gallusser A. and Kirchhausen T. (1993) The β1 and β2 subunits of the AP complexes are the clathrin coat assembly components. EMBO J. 12: 5237-5244
25. Shih W., Gallusser A. and Kirchhausen T. (1995) A clathrinbinding site in the hinge of the β2 chain of mammalian AP-2 complexes. J. Biol. Chem. 270: 31083-31090
26. Peeler J. S., Donzell W. C. and Andersen R. G. (1993) The appendage domain of the AP-2 subunit is not required for assembly or invagination of clathrin-coated pits. J. Cell Biol. 120: 47-54
27. Traub L. M., Kornfeld S. and Ungewickell E. (1995) Different domains of the AP-1 adaptor complex are required for Golgi membrane binding and clathrin recruitment. J. Biol. Chem. 270: 4933-4942
28. Zaremba S. and Keen J. H. (1985) Limited proteolytic digestion of coated vesicle assembly polypeptides abolishes reassembly activity. J. Cell Biochem. 28: 47-58
29. Wilson I. A., Niman H. L., Houghten R. A., Cherenson A. R., Connolly M. L. and Lerner R. A. (1984) The structure of an antigenic determinant in a protein. Cell 37: 767-778
30. Southern P. J. and Berg P. (1982) Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Molec. Appl. Sci. 1: 327-341
31. Morgenstern J. P. and Land H. (1990) Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18: 3587-3596
32. Chakrabarti R., Joly M. and Corvera S. (1993) Redistribution of clathrin-coated vesicle adaptor complexes during adipocytic differentiation of 3T3-L1 cells. J. Cell Biol. 123: 79- 87
33. Tebar F., Sorkina T., Sorkin A., Ericsson M. and Kirchhausen T. (1996) Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits. J. Biol. Chem. 271: 28727-28730
34. Ahle S., Mann A., Eichelsbacher U. and Ungewickell E. (1988) Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane. EMBO J. 7: 919-929
35. Keen J. H., Willingham M. C. and Pastan I. H. (1976) Clathrin-coated vesicles: isolation, dissociation and factor-dependent reassociation of clathrin baskets. Cell 16: 303-312
36. Page L. J. and Robinson M. S. (1995) Targeting signals and subunit interactions in coated vesicle adaptor complexes. J. Cell Biol. 131: 619-630
37. Traub L. M., Bannykh S. I., Rodel J. E., Aridor M., Balch W. E. and Kornfeld S. (1996) AP-2 containing clathrin coats assemble on mature lysosomes. J. Cell. Biol. 135: 1801-1814
38. Wilde A. and Brodsky F. M. (1996) In vivo phosphorylation of adaptors regulates their interaction with clathrin. J. Cell Biol. 135: 635-645
39. Schroder S. and Ungewickell E. (1991) Subunit interaction and function of clathrin-coated vesicle adaptors from the Golgi and the plasma membrane. J. Biol. Chem. 266: 7910-7918
40. Goodman O. B. Jr. and Keen J. H. (1995) The α chain of the AP-2 adaptor is a clathrin binding subunit. J. Biol. Chem. 270: 23768-23773