Actin polymerisation in neutrophils of rheumatoid arthritis patients in relation to treatment with non-steroidal anti-inflammatory drugs

Clinica Chimica Acta

Volumn 261, Issue 1, 1997, Pages 19-25

  De Clerck, L S ^a   Mertens, A V ^a   De Gendt, C M ^a   Bridts, C H ^a   Stevens, W J ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Actin; Neutrophil; NSAIDS; Rheumatoid arthritis

Indexed keywords

F ACTIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; NONSTEROID ANTIINFLAMMATORY AGENT; SALAZOSULFAPYRIDINE;

ARTICLE; BONE MARROW TOXICITY; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPOLYMERIZATION; GASTROINTESTINAL TOXICITY; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; NEUTROPHIL; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN CONTENT; RASH; RHEUMATOID ARTHRITIS; TREATMENT OUTCOME;

ACTINS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, RHEUMATOID; BIOPOLYMERS; DRUG SYNERGISM; HUMANS; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; SULFASALAZINE;

EID: 0030962502     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(96)06505-9     Document Type: Article

References (12)

1. Kitsis E, Weissmann G. The role of the neutrophil in rheumatoid arthritis. Clin Orthop Relat R 1991;265:63-72.
2. Rogers KR. The cytoskeleton and its importance as a mediator of inflammation. Ann Rheum Dis 1992;51:565-571.
3. Wallace PJ, Wersto RP, Packman CH, Lichtman MA. Chemotactic peptide-induced changes in neutrophil actin conformation. J Cell Biol 1984;99:1060-1065.
4. 2-production and degranulation. J Leukocyte Biol 1991;49:236-244.
5. Rhodes JM, Batholomew TC, Jewell DP. Inhibition of leucocyte motility by drugs used in ulcerative colitis. Gut 1981;22:642-647.
6. Carlin G. Djursäter R, Smedegard G. Inhibitory effects of sulfasalazine and related compounds on superoxide production by human polymorphonuclear leukocytes. Pharmacol Toxicol 1989;65:121-127.
7. Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-324.
8. Sacchi F, Augustine NH, Coello MM, Morris EZ, Hill HR. Abnormality in actin polymerization associated with defective chemotaxis in neutrophils from neonates. Int Arch Allergy Appl Immunol 1987;84:32-39.
9. 2 production and secretion but inhibits migration of activated human neutrophils. J Clin Invest 1988;82:1376-1382.
10. Hassalen SR, Ahrenholz DH, Solem LD, Nelson RD. Actin polymerization contributes to neutrophil chemotactic dysfunction following thermal injury. J Leukocyte Biol 1992;52:495-500.
11. Abramson SB, Weissmann G. The mechanisms of action of nonsteroidal antiinflammatory drugs. Arthritis Rheum 1989;32:1-9.
12. Minta JO, Williams MD. Some non steroidal antiinflammatory drugs inhibit the generation of superoxide anions by activated polymorphs by blocking ligand-receptor interactions. J Rheumatol 1985;12:751-757.