Molecular Mechanisms of Parathyroid Hyperplasia and Neoplasia

Hormone Research in Paediatrics

Volumn 47, Issue 4-6, 1997, Pages 194-198

  Luisa Brandi, Maria ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Antioncogenes; Hyperplasia; Neoplasia; Oncogenes; Parathyroid

Indexed keywords

CALCIUM; GROWTH FACTOR; PROTEIN P53;

CARCINOGENESIS; CHROMOSOME 11Q; CONFERENCE PAPER; DIFFERENTIAL DIAGNOSIS; GENE MUTATION; GENETIC ANALYSIS; HUMAN; MOLECULAR BIOLOGY; ONCOGENE; PARATHYROID ADENOMA; PARATHYROID CARCINOMA; PARATHYROID HYPERPLASIA; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

CALCIUM; CLONE CELLS; GROWTH SUBSTANCES; HUMANS; HYPERPLASIA; ONCOGENES; PARATHYROID GLANDS; PARATHYROID NEOPLASMS;

EID: 0030960617     PISSN: 16632818     EISSN: 16632826     Source Type: Journal    
DOI: 10.1159/000185464     Document Type: Article

References (32)

1. Studer H, Dcrwahl M: Mechanisms of nonnco-plastic endocrine hyperplasia: A changing concept, A review focused on ihe thyroid gland, F.ndocr Rev 1995:16:411-427.
2. Brandi ML, Aurbach GD, Fitzpatrick LA, Quarto R, Spiegel AM, liliziotcs ML, Norton JA, Doppman JL, Marx SJ: Parathyroid mito-genic activity in plasma from patients with familial multiple endocrine neoplasia tvpc I, N Engl J Med 1986;314:1287-1293.
3. Zimering MB, Brandi ML, DeGrange DA: Circulating fibroblast growth factor-like substance in familial multiple endocrine neoplasia type I, J Clin Endocrinol Metab 1990:70:149-154.
4. Zimering MB, Katsumata N, Sato Y, Brandi ML, Aurbach GD, Marx SJ, Friesen HG: Increased basic fibroblast growth factor in plasma from multiple endocrine neoplasia type 1: Relation to pituitary tumor, J Clin Endocrinol Metab 1993:76:1182-1187.
5. D'Adda T, Amorosi A, Bussolati G, et al: Quantitative differences in parathyroid endothelial component between MEN-1 syndrome and secondary hyperparathvroidism, Patholo-gia 1992:325:76-77.
6. Friedman E, Larsson C, Amorosi A, Brandi ML, Bale AE, Metz DC, Jensen RT, Skarulis MC, Eastman RC, Nieman I., Norton JA, Marx SJ: Multiple endocrine neoplasia type 1: Pathology, pathophysiology, molecular genetics, and differential diagnosis; in Bilczikian JP, Levine MA, Marcus R (cds): The Parathyroids, New York, Raven Press, 1994, pp 647-680.
7. Arnold A, Kim HG, Gaz RD, et al: Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma, J Clin Invest 1989: 83:2034-2040.
8. Friedman E, Sakaguchi K, Bale AE, Falchctti A, Streeten E, Zimering M, Weinstein L, McBride W, Nakamura Y, Brandi ML, Norton J A, Aurbach GD, Spiegel A, Marx SJ: Clonality of parathyroid tumors in familial multiple endocrine neoplasia type 1, N Engl J Med 1989; 321:213-218.
9. Thakkcr RV, Bouloux P, Wooding C, Chotai K, Broad PM, Spurr NK, Besser GM, O’Rior-dan JL: Association of parathyroid tumors in multiple endocrine neoplasia type I with loss of alleles on chromosome 11, N Engl J Med 1989: 321:218-224.
10. Rosenberg CL, Kim HG, Shows TB, Kronen-berg HM, Arnold A: Rearrangement and over-expression of Dl IS287E, a candidate oncogene on chromosome 11 q 13 in benign parathyroid tumors, Oncogene 1991:6:449-453.
11. Bianchi S, Fabiani S, Muratori M, Arnold A, Sakaguchi K, Miki T, Brandi ML: Calcium modulates the cyclin Dl expression in a rat parathyroid cell line, Biochcm Biophys Res Comm un 1994;204:691-700.
12. Bos JL: Ras oncogenes in human cancer: A review, Cancer Res 1989:49:4682-4689.
13. Friedman E, Bale AE, Marx SJ, Norton JA, Spiegel AM: Genetic abnormalities in sporadic parathyroid adenomas, J Clin Endocrinol Metab 1990;71:293-297.
14. Ponder BAJ, Eng C, Smith DP: Mutations of the ret protooncogcnc in the multiple endocrine neoplasia type 2 syndromes and in hirsch-sprungdisease: in Fortner JG, Rhoads JE (cds): Accomplishments in Cancer Research, Philadelphia, Lippincott, 1994, pp 118-132.
15. Mulligan LM, Eng C, Healey CS, Clayton D, Kwok JB, Gardner E, Ponder MA, Frilling A, Jackson CE, Lchnert H, et al: Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN2A and FMTC, Nat Genet 1994;6:20-24.
16. Pachnis V, Mankcio B, Costantini F: Expression of the c-ret proto-oncogene during mouse embryogencsis, Development 1993; 119:1005-1017.
17. Pausova Z, Janicic N, Konrad E, Soliman E, Goltzman D, Hendy GN: Analysis of the ret proto-oncogene in sporadic parathyroid tumors (abstract 122), 16th Meet Am Soc Bone Mineral Res, 1994.
18. Crvns VL, Yi SM, Tahara H, Gaz RD, Arnold A: Frequent loss of chromosome arm lp in parathyroid adenomas, Genes Chromosomes Cancer 1995;13:9-17.
19. Arnold A, Brown MF, Urena P, Gaz RD, Sarfa-ti E, DruekeTB: Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia, J Clin Invest 1995:95: 2047-2053.
20. Cryns VL, Thor A, Xu HJ, Hu SX, Wierman ME, Vickery AL, Benedict WF, Arnold A: Loss of the retinoblastoma tumor-suppressor gene in parathyroid carcinoma, N Engl J Med 1994: 330:757-761.
21. Cryns VL, Rubio MP, Thor AD, Louis DN, Arnold A: p53 abnormalities in human parathyroid carcinoma, J Clin Endocrinol Metab 1994:78:1320-1324.
22. Streeten EA, Weinstein LS, Norton JA, Mulvi-hill JJ, White BJ, Friedman E, Jaffe G, Brandi ML, Stewart K, Zimering MB, Spiegel AM, Aurbach GD, Marx SJ: Studies in a kindred with parathyroid carcinoma, J Clin Endocrinol Metab 1992:75:362-366.
23. Falchctti A, Bale AE, Amorosi A, Bordi C, Cic-chi P, Batidini S, Marx SJ, Brandi ML: Progression of uremic hyperparathyroidism involves allelic loss on chromosome 11, J Clin Endocrinol Metab 1993:76:139-144.
24. Poliak MR, Brown EM, Chou YH, Hebert SC, Marx SJ, Steinman B, Levi T, Seidman CE, Scidman JG: Mutations in the human calcium-sensing receptor gene cause familial hypocal-ciuric hypercalcemia and neonatal severe hyperparathyroidism, Cell 1993:75:1297-1303.
25. Hosokawa Y, Poliak MR, Brown EM, Arnold A: The extracellular calcium sensing receptor gene in human parathyroid tumors, J Clin Endocrinol Metab 1995:80:3107—3110.
26. Thompson DB, Samowitz WS, Odelberg S, Davis RK, Szabo J, Health H III: Genetic abnormalities in sporadic parathyroid adenomas: Loss of heterozygosity for chromosome 3q markers flanking the calcium receptor locus, J Clin Endocrinol Metab 1995;80:3377-3380.
27. Sandelin K, Auer G, Bondeson L, Grimelius L, Famebo L-O: Prognostic factors in parathyroid canccr: A review of 95 cases, World J Surg 1987:16:724-731.
28. Levin KE, Galante M, Clark OH: Parathyroid carcinoma versus parathyroid adenoma in patients with profound hypercalcemia, Surgery 1987:101:649-660.
29. Anderson BJ, Samaan NA, Vassilopoulou-Sel-lin R, Ordonez NG, Hickey RC: Parathyroid carcinoma: Features and difficulties in diagnosis and management, Surgery 1983,94:906-915.
30. Kav S, Hume DM: Carcinoma of the parathyroid gland: how reliable arc the clinical and histologic features? Arch Pathol 1973:96:316-319.
31. Mallette LE: DNA quantitation in the study of parathyroid lesions, A review, Am J Clin Pathol 1992:98:305-311.
32. Beckers A, Abs R, Rcvniers E, De Boulle K, Stevcnaert A, Heller FR, Klöppel G, Meurisse M, Willems PJ: Variable regions of chromosome 11 loss in different pathological tissues of a patient with the multiple cndocrinc neoplasia type 1 syndrome, J Clin Endocrinol Metab 1994;79:1498-1502.