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Volumn 35, Issue 5, 1997, Pages 337-346

Immune responses towards intestinal bacteria - Current concepts and future perspectives

Author keywords

Crohn's disease; enteroinvasive bacteria; enterotoxigenic bacteria; infection; intestinal flora; mucosal immunity; reactive arthritis; ulcerative colitis

Indexed keywords

CROHN DISEASE; ESCHERICHIA COLI; HUMAN; IMMUNE RESPONSE; INFECTION; INTESTINE FLORA; INTESTINE MUCOSA; REACTIVE ARTHRITIS; REVIEW; ULCERATIVE COLITIS; VIBRIO CHOLERAE; YERSINIA ENTEROCOLITICA;

EID: 0030960427     PISSN: 00442771     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (34)

References (78)
  • 1
    • 0023146356 scopus 로고
    • The regulation of immune responses to dietary protein antigens
    • Mowat AM. The regulation of immune responses to dietary protein antigens. Immunol Today 1987; 93-8
    • (1987) Immunol Today , pp. 93-98
    • Mowat, A.M.1
  • 2
    • 0039922399 scopus 로고    scopus 로고
    • Host defenses at mucosal surfaces
    • Rich RR (ed.). Mosby: St. Louis
    • Kelsall BL, Strober W. Host defenses at mucosal surfaces. In: Rich RR (ed.). Clinical Immunology. (Mosby: St. Louis) 1996; 299-332
    • (1996) Clinical Immunology , pp. 299-332
    • Kelsall, B.L.1    Strober, W.2
  • 3
    • 0024389095 scopus 로고
    • Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes
    • Brandtzaeg P, Halstensen TS, Kett K et al. Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes. Gastroenterol 1989; 97: 1562-8
    • (1989) Gastroenterol , vol.97 , pp. 1562-1568
    • Brandtzaeg, P.1    Halstensen, T.S.2    Kett, K.3
  • 4
    • 0001660029 scopus 로고
    • Human gastrointestinal mucosal T cells
    • Ogra PL, Strober W (eds.). Academic Press: San Diego
    • James SP, Zeitz M. Human gastrointestinal mucosal T cells. In: Ogra PL, Strober W (eds.). Hand-book of Mucosal Immunology (Academic Press: San Diego) 1994; 275-85
    • (1994) Hand-book of Mucosal Immunology , pp. 275-285
    • James, S.P.1    Zeitz, M.2
  • 5
    • 0030067796 scopus 로고    scopus 로고
    • Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyers patch
    • Kelsall B, Strober W. Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyers patch. J Exp Med 1996; 183: 237-47
    • (1996) J Exp Med , vol.183 , pp. 237-247
    • Kelsall, B.1    Strober, W.2
  • 6
    • 0025838190 scopus 로고
    • Pheno-type and function of lamina propria T-lymphocytes
    • Zeitz M, Schieferdecker HL, Ullrich R et al. Pheno-type and function of lamina propria T-lymphocytes. Immunol Res 1991; 10: 199-206
    • (1991) Immunol Res , vol.10 , pp. 199-206
    • Zeitz, M.1    Schieferdecker, H.L.2    Ullrich, R.3
  • 7
    • 0023845341 scopus 로고
    • Mucosal T cells provide helper function but do not proliferate when stimulated by specific antigen in lymphogranuloma venereum proctitis in nonhuman primates
    • Zeitz M, Quinn TC, Graeff AS, James SP. Mucosal T cells provide helper function but do not proliferate when stimulated by specific antigen in lymphogranuloma venereum proctitis in nonhuman primates. Gastroenterology 1988; 94: 353-66
    • (1988) Gastroenterology , vol.94 , pp. 353-366
    • Zeitz, M.1    Quinn, T.C.2    Graeff, A.S.3    James, S.P.4
  • 8
    • 0002428852 scopus 로고
    • Remarks on a cutaneous affliction, produced by certain poisonous vegetables
    • Dakin R. Remarks on a cutaneous affliction, produced by certain poisonous vegetables. Am J Med Sci 1829; 4: 98-100
    • (1829) Am J Med Sci , vol.4 , pp. 98-100
    • Dakin, R.1
  • 9
    • 0028358048 scopus 로고
    • Induction of anergy or active suppression following oral tolerance is determined by antigen dose
    • Friedman A, Weiner HL. Induction of anergy or active suppression following oral tolerance is determined by antigen dose. PNAS 1994; 91: 6688-92
    • (1994) PNAS , vol.91 , pp. 6688-6692
    • Friedman, A.1    Weiner, H.L.2
  • 10
    • 0029031681 scopus 로고
    • Peripheral deletion of antigen-reactive ZT cells in oral tolerance
    • Chen Y, Inobe J, Marks R et al. Peripheral deletion of antigen-reactive ZT cells in oral tolerance. Nature 1995; 376: 177-80
    • (1995) Nature , vol.376 , pp. 177-180
    • Chen, Y.1    Inobe, J.2    Marks, R.3
  • 11
    • 0028202792 scopus 로고
    • Oral tolerance: Immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens
    • Weiner HL, Friedman A, Miller A et al. Oral tolerance: Immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. Annu Rev Immunol 1994; 12: 809-17
    • (1994) Annu Rev Immunol , vol.12 , pp. 809-817
    • Weiner, H.L.1    Friedman, A.2    Miller, A.3
  • 12
    • 0005363387 scopus 로고    scopus 로고
    • Immune responses to intracellular bacteria
    • Rich RR (ed.). Mosby: St. Louis
    • Kaufmann SHE. Immune responses to intracellular bacteria. In: Rich RR (ed.). Clinical Immunology. (Mosby: St. Louis) 1996; 503-18
    • (1996) Clinical Immunology , pp. 503-518
    • Kaufmann, S.H.E.1
  • 13
    • 0021328175 scopus 로고
    • Intestinal flora in health arid disease
    • Simon GL, Gorbach SL. Intestinal flora in health arid disease. Gastroenterology 1984; 86: 174-93
    • (1984) Gastroenterology , vol.86 , pp. 174-193
    • Simon, G.L.1    Gorbach, S.L.2
  • 14
    • 0014176737 scopus 로고
    • Studies on intestinal microflora. I effects of diet, age. and periodic sampling on numbers of fecal mi croorganisms in man
    • Gorbach SL, Nahas L, Lerner PI, Weinstein L. Studies on intestinal microflora. I effects of diet, age. and periodic sampling on numbers of fecal mi croorganisms in man. Gastroenterology 1967; 53: 845-55
    • (1967) Gastroenterology , vol.53 , pp. 845-855
    • Gorbach, S.L.1    Nahas, L.2    Lerner, P.I.3    Weinstein, L.4
  • 15
    • 0000792915 scopus 로고
    • Study on the stability of the normal fecal flora
    • Zubrzycki L, Spaulding EH. Study on the stability of the normal fecal flora. J Bacteriol 1962; 83: 968-74
    • (1962) J Bacteriol , vol.83 , pp. 968-974
    • Zubrzycki, L.1    Spaulding, E.H.2
  • 16
    • 84965815714 scopus 로고
    • Discussion of current bacteriologic investigations of the relationship between intestinal flora, diet, and colon cancer
    • Moore WEG, Holdeman LV. Discussion of current bacteriologic investigations of the relationship between intestinal flora, diet, and colon cancer. Cancer Res 1975; 35: 3418-20
    • (1975) Cancer Res , vol.35 , pp. 3418-3420
    • Moore, W.E.G.1    Holdeman, L.V.2
  • 17
    • 73649204145 scopus 로고
    • Influence of the normal flora on mucosal morphology and cellular renewal in the ileum. A comparison of germ-free and conventional mice
    • Abrams G, Bauer H, Sprinz H. Influence of the normal flora on mucosal morphology and cellular renewal in the ileum. A comparison of germ-free and conventional mice. Lab Invest 1963; 12: 355-64
    • (1963) Lab Invest , vol.12 , pp. 355-364
    • Abrams, G.1    Bauer, H.2    Sprinz, H.3
  • 18
    • 0015026659 scopus 로고
    • Gastrointestinal structure and function in germ-free or gnotobiotic animals
    • Thompson G, Trexler P. Gastrointestinal structure and function in germ-free or gnotobiotic animals. Gut 1971: 12: 230-5
    • (1971) Gut , vol.12 , pp. 230-235
    • Thompson, G.1    Trexler, P.2
  • 19
    • 0018764223 scopus 로고
    • Requirement for a bacterial flora before mice generate cells capable of mediating the delayed hypersensitivity reaction to sheep red blood cells
    • MacDonald TT, Carter PB. Requirement for a bacterial flora before mice generate cells capable of mediating the delayed hypersensitivity reaction to sheep red blood cells. J Immunol 1979; 122: 2624-9
    • (1979) J Immunol , vol.122 , pp. 2624-2629
    • MacDonald, T.T.1    Carter, P.B.2
  • 20
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • Fearon DT, Locksley RM. The instructive role of innate immunity in the acquired immune response. Science 1996; 272: 50-4
    • (1996) Science , vol.272 , pp. 50-54
    • Fearon, D.T.1    Locksley, R.M.2
  • 21
    • 0026791975 scopus 로고
    • The immune system evolved to discriminate infectious nonself from noninfectious self
    • Janeway CA. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol Today 1992; 13: 11-6
    • (1992) Immunol Today , vol.13 , pp. 11-16
    • Janeway, C.A.1
  • 22
    • 0016819311 scopus 로고
    • Plasmid-controlled colonization factor associated with virulence in Escherichia coli enterotoxigenic for humans
    • Evans DG, Silver RP, Evans DJ, Chase DG, Gorbach SL. Plasmid-controlled colonization factor associated with virulence in Escherichia coli enterotoxigenic for humans. Infect Immun 1975; 12: 656-67
    • (1975) Infect Immun , vol.12 , pp. 656-667
    • Evans, D.G.1    Silver, R.P.2    Evans, D.J.3    Chase, D.G.4    Gorbach, S.L.5
  • 23
    • 0023736046 scopus 로고
    • Toxin, toxin-coregulated pili and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans
    • Herringtion DA, Hall RH, Losonsky G et al. Toxin, toxin-coregulated pili and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J Exp Med 1989; 168: 1487
    • (1989) J Exp Med , vol.168 , pp. 1487
    • Herringtion, D.A.1    Hall, R.H.2    Losonsky, G.3
  • 24
    • 0024532327 scopus 로고
    • Human immune response to Vibrio cholerae O1 whole cells and isolated outer membrane antigens
    • Richardson K, Kaper JB, Levine MM. Human immune response to Vibrio cholerae O1 whole cells and isolated outer membrane antigens. Infect Immun 1989; 57: 495-501
    • (1989) Infect Immun , vol.57 , pp. 495-501
    • Richardson, K.1    Kaper, J.B.2    Levine, M.M.3
  • 25
    • 0000346352 scopus 로고
    • The role of immunity in cholera. A review of epidemiological and serological studies
    • Mosley WH. The role of immunity in cholera. A review of epidemiological and serological studies. Texas Report Biol Med 1969; 27 (suppl. 1): 227
    • (1969) Texas Report Biol Med , vol.27 , Issue.1 SUPPL. , pp. 227
    • Mosley, W.H.1
  • 26
    • 0026012883 scopus 로고
    • New model for analysis of mucosal immunity: Intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection
    • Winner L, Mack J, Weltzin R et al. New model for analysis of mucosal immunity: Intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection. Infect Immun 1991; 59: 977-82
    • (1991) Infect Immun , vol.59 , pp. 977-982
    • Winner, L.1    Mack, J.2    Weltzin, R.3
  • 27
    • 0027486404 scopus 로고
    • Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems
    • Holmgren J, Lycke N, Czerkinsky C. Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems. Vaccine 1993; 11: 1179-84
    • (1993) Vaccine , vol.11 , pp. 1179-1184
    • Holmgren, J.1    Lycke, N.2    Czerkinsky, C.3
  • 28
    • 0024593856 scopus 로고
    • Yersinia antigens in synovial fluid cells from patients with reactive arthritis
    • Granfors K, Jalkanen S, von Essen R et al. Yersinia antigens in synovial fluid cells from patients with reactive arthritis. N Engl J Med 1989; 320: 216-21
    • (1989) N Engl J Med , vol.320 , pp. 216-221
    • Granfors, K.1    Jalkanen, S.2    Von Essen, R.3
  • 29
    • 0024592135 scopus 로고
    • Immunohistochemical and electron microscopic study of the interaction of Yersinia enterocolitica serotype 08 with intestinal mucosa during experimental enteritis
    • Hanski C, Kutschka U, Schmoranzer HP et al. Immunohistochemical and electron microscopic study of the interaction of Yersinia enterocolitica serotype 08 with intestinal mucosa during experimental enteritis. Infect Immun 1989; 57: 673
    • (1989) Infect Immun , vol.57 , pp. 673
    • Hanski, C.1    Kutschka, U.2    Schmoranzer, H.P.3
  • 30
  • 31
    • 0023013754 scopus 로고
    • Immunohistochemical analysis of plasmid-encoded proteins released by enteropathogenic Yersinia sp. grown in calcium-deficient media
    • Heesemann J, Gross U, Schmidt N, Laufs R. Immunohistochemical analysis of plasmid-encoded proteins released by enteropathogenic Yersinia sp. grown in calcium-deficient media. Infect Immun 1986; 54: 561-7
    • (1986) Infect Immun , vol.54 , pp. 561-567
    • Heesemann, J.1    Gross, U.2    Schmidt, N.3    Laufs, R.4
  • 32
    • 0024307993 scopus 로고
    • Immunohistochemical analysis of IgM, IgG, and IgA responses to plasmid encoded released proteins of Y. enterocolitica in patients with or without Yersinia triggered reactive arthritis
    • Stahlberg T, Heesemann J, Granfors K, Toivanen A. Immunohistochemical analysis of IgM, IgG, and IgA responses to plasmid encoded released proteins of Y. enterocolitica in patients with or without Yersinia triggered reactive arthritis. Ann Rheum Dis 1989; 48: 577-81
    • (1989) Ann Rheum Dis , vol.48 , pp. 577-581
    • Stahlberg, T.1    Heesemann, J.2    Granfors, K.3    Toivanen, A.4
  • 33
    • 0028881794 scopus 로고
    • Pathogen antigen- And superantigen-reactive synovial fluid T cell in reactive arthritis
    • Lahesmaa R, Soderberg C, Bliska J et al. Pathogen antigen- and superantigen-reactive synovial fluid T cell in reactive arthritis. J Infect Dis 1995; 172: 1290-7
    • (1995) J Infect Dis , vol.172 , pp. 1290-1297
    • Lahesmaa, R.1    Soderberg, C.2    Bliska, J.3
  • 34
    • 0027379849 scopus 로고
    • Identification of the Yersinia enterocolitica urease β subunit as a target antigen for human synovial T-lymphocytes in reactive arthritis
    • Probst P, Hermann E, Meyer zum Büschenfelde KH, Fleischer B. Identification of the Yersinia enterocolitica urease β subunit as a target antigen for human synovial T-lymphocytes in reactive arthritis. Infect Immun 1993; 61: 4507-9
    • (1993) Infect Immun , vol.61 , pp. 4507-4509
    • Probst, P.1    Hermann, E.2    Meyer Zum Büschenfelde, K.H.3    Fleischer, B.4
  • 35
    • 0026584819 scopus 로고
    • Yersinia enterocolitica produces superantigenic activity
    • Stuart PM, Woodward JG. Yersinia enterocolitica produces superantigenic activity. J Immunol 1992; 148: 225-33
    • (1992) J Immunol , vol.148 , pp. 225-233
    • Stuart, P.M.1    Woodward, J.G.2
  • 36
    • 0026535040 scopus 로고
    • HLA-B27 and disease: A consequence of inadvertent antigen presentation?
    • Benjamin R, Parham P. HLA-B27 and disease: A consequence of inadvertent antigen presentation? Rheum Dis Clin North Am 1992; 18: 11-21
    • (1992) Rheum Dis Clin North Am , vol.18 , pp. 11-21
    • Benjamin, R.1    Parham, P.2
  • 37
    • 0027328672 scopus 로고
    • HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis
    • Hermann E, Yu DTY, Meyer zum Büschenfelde KH, Fleischer B. HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis. Lancet 1993; 342: 646-50
    • (1993) Lancet , vol.342 , pp. 646-650
    • Hermann, E.1    Yu, D.T.Y.2    Meyer Zum Büschenfelde, K.H.3    Fleischer, B.4
  • 38
    • 0030064721 scopus 로고    scopus 로고
    • HLA-B27 restricted CTL responses are dominated by closely related TCR-Vβ gene segments. A study of Yersinia enterocolitica-specific and autoreactive synovial CD8+ T cells in reactive arthritis
    • Duchmann R, May E, Ackermann B et al. HLA-B27 restricted CTL responses are dominated by closely related TCR-Vβ gene segments. A study of Yersinia enterocolitica-specific and autoreactive synovial CD8+ T cells in reactive arthritis. Scand J Immunol 1996; 43: 101-8
    • (1996) Scand J Immunol , vol.43 , pp. 101-108
    • Duchmann, R.1    May, E.2    Ackermann, B.3
  • 39
    • 0029820442 scopus 로고    scopus 로고
    • T cell receptor β junctional regions from HLA-B27-restricted T cells and HLA-B27 binding peptides display conserved hydropathy profiles in the absence of primary sequence homology
    • May E, Duchmann R, Ackermann B, Meyer zum Büschenfelde KH, Märker-Hermann E. T cell receptor β junctional regions from HLA-B27-restricted T cells and HLA-B27 binding peptides display conserved hydropathy profiles in the absence of primary sequence homology. Int Immunology, 1996; 8: 1815-23
    • (1996) Int Immunology , vol.8 , pp. 1815-1823
    • May, E.1    Duchmann, R.2    Ackermann, B.3    Meyer Zum Büschenfelde, K.H.4    Märker-Hermann, E.5
  • 40
    • 0027938077 scopus 로고
    • Bacteria-specific cytotoxic CD8+ T cells: A missing link in the pathogenesis of the HLA-B27-associated spondylarthropathies
    • Hermann E, Fleischer B, Meyer zum Büschenfelde KH. Bacteria-specific cytotoxic CD8+ T cells: A missing link in the pathogenesis of the HLA-B27-associated spondylarthropathies. Ann Med 1994; 26: 365-9
    • (1994) Ann Med , vol.26 , pp. 365-369
    • Hermann, E.1    Fleischer, B.2    Meyer Zum Büschenfelde, K.H.3
  • 41
    • 8244249049 scopus 로고
    • Pathogenesis and clinical implications: Where do we stand, where do we go?
    • Goebell H, Marchow H, Ewe K, Koelbel CH (ed.). Kluwer Academic Publishers, Oxford
    • Fiocchi C. Pathogenesis and clinical implications: Where do we stand, where do we go? In: Goebell H, Marchow H, Ewe K, Koelbel CH (ed.). Inflammatory bowel diseases. Progress in basic research and clinical implications (Kluwer Academic Publishers, Oxford) 1991
    • (1991) Inflammatory Bowel Diseases. Progress in Basic Research and Clinical Implications
    • Fiocchi, C.1
  • 42
    • 0001705106 scopus 로고
    • Experimental studies on the etiology of chronic ulcerative colitis
    • Bargan J. Experimental studies on the etiology of chronic ulcerative colitis. J Am Med Assoc 1924; 83: 332-6
    • (1924) J Am Med Assoc , vol.83 , pp. 332-336
    • Bargan, J.1
  • 43
    • 84930302282 scopus 로고
    • Regional Ileitis: A pathogenic and clinical entity
    • Crohn B, Ginzburg L, Oppenheimer GD. Regional Ileitis: A pathogenic and clinical entity. JAMA 1932; 99: 1323-8
    • (1932) JAMA , vol.99 , pp. 1323-1328
    • Crohn, B.1    Ginzburg, L.2    Oppenheimer, G.D.3
  • 44
    • 0021709791 scopus 로고
    • Possible role of mycobacteria in inflammatory bowel disease. I. An unclassified mycobacterium species isolated from patients with Crohn's disease
    • Chiodini R, Van Kruiningen H, Thayer W, Merkal S, Coutu J. Possible role of mycobacteria in inflammatory bowel disease. I. An unclassified mycobacterium species isolated from patients with Crohn's disease. Dig Dis Sci 1984; 29: 1073-9
    • (1984) Dig Dis Sci , vol.29 , pp. 1073-1079
    • Chiodini, R.1    Van Kruiningen, H.2    Thayer, W.3    Merkal, S.4    Coutu, J.5
  • 45
    • 0021208056 scopus 로고
    • Patients with active Crohn's disease have elevated serum antibodies to antigens from seven enteric bacterial pathogens
    • Blaser MJ, Miller RA, Lacher J et al. Patients with active Crohn's disease have elevated serum antibodies to antigens from seven enteric bacterial pathogens. Gastroenterology 1984; 87: 888-94
    • (1984) Gastroenterology , vol.87 , pp. 888-894
    • Blaser, M.J.1    Miller, R.A.2    Lacher, J.3
  • 46
    • 0028901664 scopus 로고
    • Immunocytochemical evidence of Listeria, Escherichia coli, and Streptococcus antigens in Crohn's disease
    • Liu Y, Van Kruiningen H, West A et al. Immunocytochemical evidence of Listeria, Escherichia coli, and Streptococcus antigens in Crohn's disease. Gastroenterology 1995; 108: 1396-1404
    • (1995) Gastroenterology , vol.108 , pp. 1396-1404
    • Liu, Y.1    Van Kruiningen, H.2    West, A.3
  • 47
    • 0019489932 scopus 로고
    • Studies on isolated gut mucosal lymphocytes in inflammatory bowel disease. Detection of activated T-cells and enhanced proliferation to Staphylococcus aureus and lipopoly-saccharides
    • Fiocchi C, Battisto J, Farmer R. Studies on isolated gut mucosal lymphocytes in inflammatory bowel disease. Detection of activated T-cells and enhanced proliferation to Staphylococcus aureus and lipopoly-saccharides. Dig Dis Sci 1981; 26: 728-36
    • (1981) Dig Dis Sci , vol.26 , pp. 728-736
    • Fiocchi, C.1    Battisto, J.2    Farmer, R.3
  • 48
    • 0026570561 scopus 로고
    • Mucosal cell-mediated immunity to mycobacterial, enterobacterial and other microbial antigens in inflammatory bowel disease
    • Ibbotson JP, Lowes JR, Chahal H et al. Mucosal cell-mediated immunity to mycobacterial, enterobacterial and other microbial antigens in inflammatory bowel disease. Clin Exp Immunol 1992; 87: 224-30
    • (1992) Clin Exp Immunol , vol.87 , pp. 224-230
    • Ibbotson, J.P.1    Lowes, J.R.2    Chahal, H.3
  • 50
    • 0029931508 scopus 로고    scopus 로고
    • T cell clones from peripheral blood and human intestine are selective in their reactivity towards enterobacteria or H. pylori and isolated with increased frequency from inflamed in-flammatory bowel intestine
    • Duchmann R, Kaiser I, Märker-Hermann E, Meyer zum Büschenfelde KH. T cell clones from peripheral blood and human intestine are selective in their reactivity towards enterobacteria or H. pylori and isolated with increased frequency from inflamed in-flammatory bowel intestine. Scand J Immunol 1996; 44: 71-6
    • (1996) Scand J Immunol , vol.44 , pp. 71-76
    • Duchmann, R.1    Kaiser, I.2    Märker-Hermann, E.3    Meyer Zum Büschenfelde, K.H.4
  • 51
    • 4243296821 scopus 로고
    • T cell receptor Vβ expression in inflammatory bowel disease lamina propria lymphocytes: Evidence for altered Vβ gene usage
    • Duchmann R, Strober W, Fiocchi C, Ailing D, James SP. T cell receptor Vβ expression in inflammatory bowel disease lamina propria lymphocytes: Evidence for altered Vβ gene usage. Inflammatory Bowel Diseases 1995; 1: 184-92
    • (1995) Inflammatory Bowel Diseases , vol.1 , pp. 184-192
    • Duchmann, R.1    Strober, W.2    Fiocchi, C.3    Ailing, D.4    James, S.P.5
  • 52
    • 0025339265 scopus 로고
    • T cell antigen receptor V gene usage. Increases in Vβ8+ T cells in Crohn's disease
    • Posnett D, Schmelkin I, Burton D et al. T cell antigen receptor V gene usage. Increases in Vβ8+ T cells in Crohn's disease. J Clin Invest 1990; 85: 1770-6
    • (1990) J Clin Invest , vol.85 , pp. 1770-1776
    • Posnett, D.1    Schmelkin, I.2    Burton, D.3
  • 53
    • 0024498413 scopus 로고
    • Treatment of ulcerative colitis by implantation of normal colonic flora
    • Bennet JD, Brinkman M. Treatment of ulcerative colitis by implantation of normal colonic flora. Lancet 1989; 1: 164
    • (1989) Lancet , vol.1 , pp. 164
    • Bennet, J.D.1    Brinkman, M.2
  • 54
    • 0015411247 scopus 로고
    • Immunological response of mice to members of the autochthonous intestinal microflora
    • Foo MC, Lee A. Immunological response of mice to members of the autochthonous intestinal microflora. Infect Immun 1972; 6: 525-32
    • (1972) Infect Immun , vol.6 , pp. 525-532
    • Foo, M.C.1    Lee, A.2
  • 55
    • 0016633215 scopus 로고
    • Immune response of specific pathogen-free and gnotobiotic mice to antigens of indigenous and non-indigenous microorganisms
    • Berg R, Savage D. Immune response of specific pathogen-free and gnotobiotic mice to antigens of indigenous and non-indigenous microorganisms. Infect Immun 1975; 11: 320-9
    • (1975) Infect Immun , vol.11 , pp. 320-329
    • Berg, R.1    Savage, D.2
  • 56
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease
    • Duchmann R, Kaiser I, Hermann E et al. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease. Clin Exp Immunol 1995; 102: 448-55
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Kaiser, I.2    Hermann, E.3
  • 57
    • 0029993786 scopus 로고    scopus 로고
    • Tolerance towards resident intestinal flora in mice is abrogated in ex- Perimental colitis and restored by treatment with Interleukin-10 antibodies to Interleukin-12
    • Duchmann R, Schmitt E, Knolle P, Meyer zum Büschenfelde KH, Neurath M. Tolerance towards resident intestinal flora in mice is abrogated in ex- perimental colitis and restored by treatment with Interleukin-10 antibodies to Interleukin-12. Eur J Immunol 1996; 26: 934-8
    • (1996) Eur J Immunol , vol.26 , pp. 934-938
    • Duchmann, R.1    Schmitt, E.2    Knolle, P.3    Meyer Zum Büschenfelde, K.H.4    Neurath, M.5
  • 58
    • 0030585621 scopus 로고    scopus 로고
    • Enteropathische Spondarthritiden bei chronisch entzündlichen Darmerkrankungen: Prävalenz, Befallsmuster und HLA-Assoziation
    • Protzer U, Duchmann R, Höhler T et al. Enteropathische Spondarthritiden bei chronisch entzündlichen Darmerkrankungen: Prävalenz, Befallsmuster und HLA-Assoziation. Med Klin 1996; 91: 330-5
    • (1996) Med Klin , vol.91 , pp. 330-335
    • Protzer, U.1    Duchmann, R.2    Höhler, T.3
  • 59
    • 0025887076 scopus 로고
    • Effeet of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum
    • Rutgeerts P, Goboes K, Peeters M et al. Effeet of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum. Lancet 1991; 338: 771-4
    • (1991) Lancet , vol.338 , pp. 771-774
    • Rutgeerts, P.1    Goboes, K.2    Peeters, M.3
  • 60
    • 0027217379 scopus 로고
    • Intestinal permeability and the prediction of relapse in Crohn's disease
    • Wyatt J, Vogelsang H, Hubl W, Waldhoer T, Lochs H. Intestinal permeability and the prediction of relapse in Crohn's disease. Lancet 1993; 341: 1437
    • (1993) Lancet , vol.341 , pp. 1437
    • Wyatt, J.1    Vogelsang, H.2    Hubl, W.3    Waldhoer, T.4    Lochs, H.5
  • 61
    • 0021924786 scopus 로고
    • Granulomatous enterocolitis induced in rats by purified bacterial cell wall fragments
    • Sartor R, Cromartie W, Powell D, Schwab J. Granulomatous enterocolitis induced in rats by purified bacterial cell wall fragments. Gastroenterology 1985; 89: 587-95
    • (1985) Gastroenterology , vol.89 , pp. 587-595
    • Sartor, R.1    Cromartie, W.2    Powell, D.3    Schwab, J.4
  • 63
    • 4243962380 scopus 로고
    • Luminal bacteria and bacterial polymers potentiate indomethacm-induced intestinal injury in rats
    • Davis SW, Holt LC, Sartor RB. Luminal bacteria and bacterial polymers potentiate indomethacm-induced intestinal injury in rats, Gastroenterology 1990; 98: 444 A
    • (1990) Gastroenterology , vol.98
    • Davis, S.W.1    Holt, L.C.2    Sartor, R.B.3
  • 64
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • Sadlack B, Merz H, Schorle H et al. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993; 75: 253-61
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1    Merz, H.2    Schorle, H.3
  • 65
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn R, Löhler J, Rennick D, Rajewski K, Müller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993; 75: 263-74
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Löhler, J.2    Rennick, D.3    Rajewski, K.4    Müller, W.5
  • 66
    • 0025633436 scopus 로고
    • Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: An animal model of HLA-B27-associated human disorders
    • Hammer RE, Maika SD, Richardson JA, Tang JP, Taurog JD. Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: An animal model of HLA-B27-associated human disorders. Cell 1990; 63: 1099-112
    • (1990) Cell , vol.63 , pp. 1099-1112
    • Hammer, R.E.1    Maika, S.D.2    Richardson, J.A.3    Tang, J.P.4    Taurog, J.D.5
  • 67
    • 0027422089 scopus 로고
    • Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice
    • Strober W, Ehrhardt RO. Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice. Cell 1993; 75: 203-5
    • (1993) Cell , vol.75 , pp. 203-205
    • Strober, W.1    Ehrhardt, R.O.2
  • 68
    • 0028941437 scopus 로고
    • Novel experimental approaches in the study of the immunopathology in inflammatory bowel disease
    • Reimann J, Rudolphi A, Claesson M. Novel experimental approaches in the study of the immunopathology in inflammatory bowel disease. J Mol Med 1995; 73: 133-40
    • (1995) J Mol Med , vol.73 , pp. 133-140
    • Reimann, J.1    Rudolphi, A.2    Claesson, M.3
  • 69
    • 0028861975 scopus 로고
    • Antibodies to Interleukin-12 abrogate established experimental colitis in mice
    • Neurath M, Fuss I, Kelsall BL, Stüber E, Strober W. Antibodies to Interleukin-12 abrogate established experimental colitis in mice. J Exp Med 1995; 182: 1281-90
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.1    Fuss, I.2    Kelsall, B.L.3    Stüber, E.4    Strober, W.5
  • 70
    • 0026801444 scopus 로고
    • Cholera as a model for research on mucosal immunity and development of oral vaccines
    • Holmgren J, Czerkinsky C. Cholera as a model for research on mucosal immunity and development of oral vaccines. Curr Opin Immunol 1992; 4: 387-91
    • (1992) Curr Opin Immunol , vol.4 , pp. 387-391
    • Holmgren, J.1    Czerkinsky, C.2
  • 71
    • 0027395969 scopus 로고
    • Induction and assessment of immunity at enteromucosal surfaces in humans: Implications for vaccine develop ment
    • Czerkinsky C, Svennerholm AM, Holmgren J. Induction and assessment of immunity at enteromucosal surfaces in humans: Implications for vaccine develop ment. Clin Infect Dis 1993; 16 (suppl. 2): 106-16
    • (1993) Clin Infect Dis , vol.16 , Issue.2 SUPPL. , pp. 106-116
    • Czerkinsky, C.1    Svennerholm, A.M.2    Holmgren, J.3
  • 73
    • 0027818972 scopus 로고
    • Antimicrobial therapy of inflammatory bowel disease: Implications for pathogenesis and management
    • Sartor R. Antimicrobial therapy of inflammatory bowel disease: Implications for pathogenesis and management. Can J Gastroenterol 1993; 7: 132-8
    • (1993) Can J Gastroenterol , vol.7 , pp. 132-138
    • Sartor, R.1
  • 74
    • 8244238651 scopus 로고
    • Treating IBD alterating luminal contents: Rationale and response
    • Rachmilewith D (ed.). Kluwer Academic, Lancaster
    • Sartor RB. Treating IBD alterating luminal contents: Rationale and response. In: Rachmilewith D (ed.). Inflammatory bowel diseases (Kluwer Academic, Lancaster) 1994; 177-91
    • (1994) Inflammatory Bowel Diseases , pp. 177-191
    • Sartor, R.B.1
  • 75
    • 0030607893 scopus 로고    scopus 로고
    • Zytokine bei chronisch entzündlichen Darmerkrankungen
    • Neurath M, Duchmann R, Meyer zum Büschenfelde K-H. Zytokine bei chronisch entzündlichen Darmerkrankungen. DMW 1996; 121: 735-41
    • (1996) DMW , vol.121 , pp. 735-741
    • Neurath, M.1    Duchmann, R.2    Meyer Zum Büschenfelde, K.-H.3
  • 76
    • 0028907439 scopus 로고
    • Immunoregulatory role of interleukin-10 in patients with inflammatory bowel disease
    • Schreiber S, Kaftannig T, Thiele HG, Raedler A. Immunoregulatory role of interleukin-10 in patients with inflammatory bowel disease. Gastroenterology 1995; 108: 1434-44
    • (1995) Gastroenterology , vol.108 , pp. 1434-1444
    • Schreiber, S.1    Kaftannig, T.2    Thiele, H.G.3    Raedler, A.4
  • 77
    • 0016516988 scopus 로고
    • Suppression of the immune response by microorganisms
    • Schwab JH. Suppression of the immune response by microorganisms. Bacteriological reviews 1975; 39: 121-43
    • (1975) Bacteriological Reviews , vol.39 , pp. 121-143
    • Schwab, J.H.1
  • 78
    • 0029934754 scopus 로고    scopus 로고
    • Bacterial DNA induce NK cells to produce IFN-γ in vivo and increases the toxicity of lipopolysacharides
    • Cowdery JS, Chace JH, Yi AK, Krieg AM. Bacterial DNA induce NK cells to produce IFN-γ in vivo and increases the toxicity of lipopolysacharides. J Immunol 1996; 156: 4570-5
    • (1996) J Immunol , vol.156 , pp. 4570-4575
    • Cowdery, J.S.1    Chace, J.H.2    Yi, A.K.3    Krieg, A.M.4


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