PCR-RFLP detection of PAI-2 gene variants: Prevalence in ethnic groups and disease relationship in patients undergoing coronary angiography

Thrombosis and Haemostasis

Volumn 77, Issue 5, 1997, Pages 955-958

  Foy, Carole A ^a,b   Grant, Peter J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 2;

ADULT; AGED; AMINO ACID SEQUENCE; ANGIOCARDIOGRAPHY; ARTICLE; ATHEROMA; CAUCASIAN; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; FIBRINOLYSIS; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; INDIAN; MAJOR CLINICAL STUDY; MALE; MONOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION SITE; STENOSIS; VASCULAR DISEASE;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; ARIZONA; CORONARY ANGIOGRAPHY; CORONARY DISEASE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; ETHNIC GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; INDIANS, NORTH AMERICAN; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PLASMINOGEN ACTIVATOR INHIBITOR 2; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; REFERENCE VALUES; VARIATION (GENETICS);

EID: 0030960262     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Kawano T, Morimoto K, Uemura Y. Urokinase inhibitor in human placenta. Nature 1968; 217: 253-4.
2. Kruithof EKO, Vassalli JD, Schleuning WD, Mattaliano RJ, Bachmann F. J Biol Chem 1986; 261: 1207-13.
3. Kruithof EKO, Tran-Thang C, Gudinchet A, Havert J, Nicoloso G, Genton C, Welti H, Bachmann F. Fibrinolysis in pregnancy. A study of plasminogen activator inhibitors. Blood 1987; 69: 460-9.
4. Semeraro N, Montemurro P, Giordano P, Santoro N, De Mattia D, Colucci M. Increased mononuclear cell tissue factor and type-2 plasminogen activator inhibitor and reduced plasma fibrinolytic capacity in children with lymphoma. Thromb Haemost 1994; 72: 54-7.
5. Scherrer A, Kruithof EKO, Grob JP. Plasminogen activator inhibitor-2 in patients with monocytic leukemia. Leukemia 1991; 5: 479-86.
6. Leung K-C, Byatt JA, Stephens RW. The resistance of fibrin-stimulated tissue plasminogen activator to inactivation by a class PAI-2 inhibitor (miniactivin). Thromb Res 1987; 46: 755-66.
7. Schleef RR, Wagner NV, Loskutoff DJ. Detection of both type 1 and type 2 plasminogen activator inhibitor. J Cell Physiol 1988; 134: 269-74.
8. Laug WE, Aebersold R, Jong A, Rideout W, Bergman BL, Baker J. Isolation of multiple types of plasminogen activator inhibitors from vascular smooth muscle cells. Thromb Haemost 1989; 61: 517-21.
9. Kruithof EKO, Baker MS, Bunn CL. Biological and clinical aspects of plasminogen activator inhibitor type 2. Blood 1995; 86: 4007-24.
10. Ritchie H, Jamieson A, Booth NA. Thrombin modulates synthesis of plasminogen activator inhibitor type 2 by human peripheral blood monocytes. Blood 1995; 86: 3428-35.
11. Feener E, Northrup J, Aiello L, King G. Angiotensin II induces plasminogen activator inhibitor-1 and -2 expression in vascular endothelial and smooth muscle cells. J Clin Invest 1995; 95: 1353-62.
12. Ritchie H, Jamieson A, Booth NA. Peripheral blood monocyte synthesis of plasminogen activator inhibitor 2 in response to native and modified LDL. Thromb Haemost 1995; 74: 1521-7.
13. Webb AC, Collins KL, Snyder SE, Alexander SJ, Rosenwasser LJ, Eddy RL, Shows TB, Auron PE. Human monocyte Arg-Serpin cDNA. Sequence, chromosomal assignment, and homology to plasminogen activator-inhibitor. J Exp Med 1987; 166: 77-94
14. Antalis TM, Clark MA, Barnes T, Lehrbach PR, Devine PL, Schevzov G, Goss NH, Stephens RW, Tolstoshev P. Cloning and expression of a cDNA coding for a human monocyte-derived plasminogen activator inhibitor. Proc Natl Acad Sci USA 1988; 85: 985-9.
15. Kiso U, Kaudewitz H, Henschen A, Åstedt B, Kruithof EKO, Bachmann F. Determination of intermediates, products and cleavage sites in the reaction between plasminogen activator inhibitor type 2 and urokinase. FEBS Lett 1988; 230: 51-6.
16. Van den Berg EA, Le Clerq E, Kooistra T, Frants RR, Bakker E. The human gene for plasminogen activator inhibitor 2 (PAI-2) exhibits an EcoRI RFLP. Nucleic Acids Res 1990; 18: 2837.
17. Young J, Antalis TM, Chenevix-Trench G. BclI RFLP of the plasminogen activator inhibitor type 2 gene (PLANH) on chromosome 18q21-q23. Nucleic Acids Res 1990; 18: 7196.
18. Ye RD, Wun TC, Sadler JE. cDNA cloning and expression in Escherichia coli of a plasminogen activator inhibitor from human placenta. J Biol Chem 1987; 262: 3718-25.
19. Mikus P, Urano T, Lijeström P, Ny T. Plasminogen-activator inhibitor type 2 (PAI-2) is a spontaneously polymerising SERPIN. Biochemical characterisation of the recombinant intracellular and extracellular forms. Eur J Biochem 1993; 218: 1071-82.
20. Mansfield MW, Stickland MH, Carter AM, Grant PJ. Polymorphisms of the plasminogen activator inhibitor-1 gene in type 1 and type 2 diabetes, and in patients with diabetic retinopathy. Thromb Haemost 1994; 71: 731-6.
21. Kruithof EKO, Gudinchet A, Bachmann F. Plasminogen activator inhibitor 1 and plasminogen activator inhibitor 2 in various disease states. Thromb Haemost 1988; 59: 7-12.
22. Dawson S, Wiman B, Hamsten A, Green F, Humphries S, Henney A. The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in Hep G2 cells. J Biol Chem 1993; 268: 10739-45.
23. Eriksson P, Kallin B, van't Hooft FM, Båvenholm P, Hamsten A. Allele-specific increase in basal transcription of the plasminogen activator inhibitor-1 gene is associated with myocardial infarction. Proc Natl Acad Sci USA 1995; 92: 1851-5.
24. Ossei-Gerning N, Mansfield MW, Stickland MH, Wilson I, Grant PJ. Plasminogen activator inhibitor-1 (PAI-1) promoter 4G/5G genotype and levels in relation to a history of myocardial infarction in patients characterised by coronary angiography. Arterioscl Thromb Vasc Biol 1996 (in press)
25. Antalis TM, Godbolt D, Donnan KD, Stringer BW. Southwestern blot mapping of potential regulatory proteins binding to the DNA encoding plasminogen activator inhibitor type 2. Gene 1993; 134: 201-8.
26. Cousin E, Medcalf RL, Bergonzelli GE, Kruithof EKO. Regulatory elements involved in constitutive and phorbol ester-inducible expression of the plasminogen activator inhibitor type 2 gene promoter. Nucleic Acid Res 1991; 19: 2881-6.
27. Dear AE, Medcalf RL. The cellular and molecular biology of plasminogen activator inhibitor type 2. Fibrinolysis 1995; 9: 321-30.