Determination of MEGX by HPLC with fluorescence detection

Clinical Chemistry

Volumn 43, Issue 6, 1997, Pages 1081-1082

  Andreeva, Maria ^a   Niedmann, Paul Dieter ^a   Schütz, Ekke Hard ^a   Wieland, Eberhard ^a   Armstrong, Victor William ^a   Oellerich, Michael ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; DEETHYLLIDOCAINE; LIDOCAINE;

ACCURACY; ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DERIVATIZATION; DRUG BLOOD LEVEL; FLUORESCENCE; FLUORESCENCE POLARIZATION IMMUNOASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER FAILURE; LIVER FUNCTION TEST; QUALITY CONTROL;

EID: 0030960109     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/43.6.1081     Document Type: Article

References (12)

1. Oellerich M, Raude E, Burdelski M, Schulz M, Schmidt FW, Ringe B, et al. Monoethylglycinexylidide formation kinetics: a novel approach to assessment of liver function. J Clin Chem Clin Biochem 1987;25:845-53.
2. Potter J, Oellerich M. The use of lidocaine as a test of liver function in liver transplantation. Liver Transplant Surg 1996;2:1-15.
3. Oellerich M, Burdelski M, Lautz HU, Binder L, Pichlmayr R. Predictors of one-year pretransplant survival in patients with cirrhosis. Hepatology 1991; 14:1029-34.
4. Burdelski M, Schutz E, Nolte-Buchholtz S, Armstrong VW, Oellerich M. Prognostic value of the MEGX-test in pediatric liver transplant candidates. Ther Drug Monit 1996;18:378-82.
5. Chen Y, Potter JM. Ruorescence polarization immunoassay and HPLC assays compared for measuring monoethylglycinexylidide in liver-transplant patients. Clin Chem 1992;38:2426-30.
6. Zoppi F, Fumagalli C. Improved measurement of MEGX in serum with the Abbott TDx [Letter]. Clin Chem 1992;38:441-2.
7. Leclercq I, Hausleithner V, Wallemacq P, Saliez A, Horsmans Y, Lambotte L. MEGX is not a reliable index of liver function or of lidocaine metabolism in rats [Abstract]. Hepatology 1996;24:466A.
8. Chen Y, Potter J. High performance liquid chromatography (HPLC): an important technique in the studies of lignocaine and its metabolism [Review]. J Liq Chromatogr 1994;17:2273-89.
9. O'Neal CL, Poklis A. Sensitive HPLC for simultaneous quantification of lidocaine and its metabolites monoethylglycinexylidide and glycinexylidide in serum [Tech Brief]. Clin Chem 1996:42:330-1.
10. Epstein E, Malatestinic N. The synthesis and pharmacology of N-(substituted aminoacyl)-chlorotoluidines II. J Am Pharm Assoc 1960:49:80-2.
11. Passing H, Bablock W. A new biometrical procedure for testing the equality of measurements from two different analytical methods. J Clin Chem Clin Biochem 1983;21:709-20.
12. Imai K. Watanabe Y. Fluorimetric determination of secondary amino acids by 7-fluoro-4-nitrobenzo-2-oxa-1,3-diazole. Anal Chim Acta 1981; 130:377-83.