Pharmacokinetics, absorption, distribution and disposition of [125I]-oligotide following intravenous or oral administration in the rat

Thrombosis Research

Volumn 85, Issue 6, 1997, Pages 445-453

  Fisher, Jackie ^a   Holland, Terry K ^a   Pescador, Rodolfo ^b   Porta, Roberto ^b   Ferro, Laura ^b  

^a Inveresk Research   (United Kingdom)

^b Crinos Biological Research Laboratories   (Italy)

Author keywords

125I oligotide; oligotide's bioavailability; oligotide's pharmacokinetics; oral administration

Indexed keywords

DEOXYRIBONUCLEOTIDE; IODINE 125; OLIGONUCLEOTIDE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; FECES; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; URINARY EXCRETION;

ABSORPTION; ADMINISTRATION, ORAL; ANIMALS; ANTITHROMBIN III; HALF-LIFE; INJECTIONS, INTRAVENOUS; IODINE RADIOISOTOPES; MALE; OLIGODEOXYRIBONUCLEOTIDES; PLATELET AGGREGATION; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 0030958998     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(97)00034-0     Document Type: Article

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