Endotoxin-induced ileal VO2-DO2 alterations do not correlate with the severity of ileal injury

Journal of Critical Care

Volumn 12, Issue 2, 1997, Pages 83-91

  Crouser, Elliott D ^a   Julian, Mark W ^b   Weisbrode, Steven E ^b   Dorinsky, Paul M ^b  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; PLASMA PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CAT; CONTROLLED STUDY; ILEUM; INTESTINE INJURY; INTESTINE LYMPH; MICROVASCULARIZATION; NONHUMAN; OXYGEN CONSUMPTION; SEPSIS; TISSUE OXYGENATION;

EID: 0030958756     PISSN: 08839441     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0883-9441(97)90005-8     Document Type: Article

References (36)

1. Bihari D, Smithies M, Gimson A, et al: The effects of vasodilatation with prostacyclin on oxygen delivery and uptake in critically ill patients. N Engl J Med 317:397-403, 1987
2. Coalson JJ, Archer LT, Benjamin BA, et al: A morphologic study of live Escherichia coli organism shock in baboons. Exp Mol Pathol 31:10-22, 1979
3. 2 alterations. Am J Respir Crit Care Med 151:A323, 1995
4. 2 alterations are not a direct effect of endotoxin and do not correlate with endothelial injury. Am J Respir Crit Care Med 151:A338, 1995
5. 2 relationship alterations after endotoxin (LPS) correlate with the extent/severity of mitochondrial injury. Am J Respir Crit Care Med 153:A466, 1996
6. 2 relationships. Am J Respir Crit Care Med 153:1965-1971, 1996
7. Dorinsky PM, Costello JL, Gadek JE: Oxygen distribution and utilization after phorbol myristate acetate-induced acute lung injury. Am Rev Respir Dis 138:1454-1463, 1988
8. Duling BR, Hogan RD, Languie BL, et al: Vasomotor control: Functional hyperemia and beyond. Fed Proc 46:251-263, 1987
9. Ellesworth ML, Pittman RN: Arterioles supply oxygen to capillaries by diffusion as well as by convection. Am J Physiol 258:H1240-H1243, 1990
10. Gattinoni L, Brazzi L, Pelosi P, et al: A trial of goaldirected hemodynamic therapy in critically ill patients. N Engl J Med 333:1025-1032, 1995
11. Gutierrez G, Bismar H, Dantzker DR, et al: Comparison of gastric intramucosal pH with measures of oxygen transport and consumption in critically ill patients. Crit Care Med 20:451-457, 1992
12. 2 supply in critically ill patients. J Crit Care 1:45-53, 1986
13. Harken AH, Lillo RS, Hufnagel HV: Direct influence of endotoxin on cellular respiration. Surg Gynecol Obstet 140:858-860, 1975
14. Hayes TM, Timmins AC, Yau EHS, et al: Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med 330:1717-1722, 1994
15. 2 metabolism in endotoxemic pigs: effect of graded hemorrhage. Circ Shock 35:44-52, 1991
16. Hersch M, Gnidec AA, Bersten AD, et al: Histologic and ultrastructural changes in nonpulmonary organs during early hyperdynamic sepsis. Surgery 107:397-410, 1990
17. 2 uptake during endotoxemia. J Appl Physiol 77:1093-1100, 1994
18. Krogh A: The supply of oxygen to the tissues and the regulation of capillary circulation. J Physiol 52:457-474, 1919
19. Manthous CA, Hall JB, Samsel RW: Endotoxin in human disease. Part 1: Biochemistry, assay, and possible role in diverse disease states. Chest 104:1572-1581, 1993
20. Mela L, Bacalzo LV, Miller LD: Defective oxidative metabolism of rat liver mitochondria in hemorrhagic and endotoxin shock. Am J Physiol (Heart Circ Physiol) 220:571-577, 1971
21. 2 consumption in the adult respiratory distress syndrome. Chest 84:267-271, 1983
22. Mortola JP, Rezzonico R, Lanthier C: Utilization and oxygen consumption during acute hypoxia in newborn mammals: A comparative study. Respir Physiol 78:31-43, 1989
23. 2 uptake during endotoxemia. J Appl Physiol 64:2410-2419, 1988
24. Ostgaard G, Reed RK: Interstitial fluid accumulation does not influence oxygen uptake in the rabbit small intestine. Acta Anaesth Scand 38:1-7, 1995
25. Pelias ME, Townsend MC: Despite maintenance of systemic and regional perfusion, endotoxemia following complement depletion produces hepatocellular dysfunction. J Surg Res 55:628-631, 1993
26. Portoles MT, Ainaga MJ, Municio AM, et al: Intracellular calcium and pH alterations induced by Escherichia coli endotoxin in rat hepatocytes. Biochem Biophys Acta 1092:1-6, 1991
27. 3 induced by endotoxin in rats. Circ Shock 33:17-25, 1991
28. Schumacker PT, Cain SM: The concept of critical oxygen delivery. Intensive Care Med 13:223-229, 1987
29. Sokal RR, Rohlf FJ: Biometry (ed 2). New York, NY, WH Freeman and Co, 1981, pp 232-262
30. St. John RC, Mizer LA, Kindt GC, et al: Acid aspiration-induced acute lung injury causes leukocyte-dependent systemic organ injury. J Appl Physiol 74:1994-2003, 1993
31. St. John RC, Mizer LA, Weisbrode SE, et al: Increased intestinal protein permeability in a model of lung injury induced by phorbol myristate acetate. Am Rev Respir Dis 144:1171-1176, 1991
32. Taylor D, Piantadosi C: Oxidative metabolism in sepsis and sepsis syndrome. J Crit Care 10:122-135, 1995
33. VanderMeer TJ, Wang H, Fink MP: Endotoxin causes ileal mucosal acidosis in the absence of mucosal hypoxia in a normodynamic model of septic shock. Crit Care Med 22:1217-1226, 1995
34. Weg JG: Oxygen transport in adult respiratory distress syndrome and other acute circulatory problems: Relationship of oxygen delivery and oxygen consumption. Crit Care Med 19:650-657, 1991
35. Wollert S, Rasmussen I, Lundberg C, et al: Inhibition of CD18-dependent adherence of polymorphonuclear leukocytes does not affect liver oxygen consumption in fecal peritonitis in pigs. Circ Shock 41:230-238, 1993
36. Zimpfer M, Mizer LA, Weisbrode SE, et al: Oxygen uptake-oxygen delivery alterations in the isolated liver after hydrogen peroxide challenge. J Crit Care 8:24-33, 1993